Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Greg N. Brooke"'
Autor:
Divya R. Jacob, Wilfried M. Guiblet, Hulkar Mamayusupova, Mariya Shtumpf, Isabella Ciuta, Luminita Ruje, Svetlana Gretton, Milena Bikova, Clark Correa, Emily Dellow, Shivam P. Agrawal, Navid Shafiei, Anastasija Drobysevskaja, Chris M. Armstrong, Jonathan D. G. Lam, Yevhen Vainshtein, Christopher T. Clarkson, Graeme J. Thorn, Kai Sohn, Madapura M. Pradeepa, Sankaran Chandrasekharan, Greg N. Brooke, Elena Klenova, Victor B. Zhurkin, Vladimir B. Teif
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-17 (2024)
Abstract Background Nucleosome repositioning in cancer is believed to cause many changes in genome organisation and gene expression. Understanding these changes is important to elucidate fundamental aspects of cancer. It is also important for medical
Externí odkaz:
https://doaj.org/article/5af71b81421e47c4ac7dca4c55e40372
Autor:
Sundarraj Jayakumar, Manthan Patel, Fanny Boulet, Hadicha Aziz, Greg N. Brooke, Hemanth Tummala, Madapura M. Pradeepa
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract R-loops that accumulate at transcription sites pose a persistent threat to genome integrity. PSIP1 is a chromatin protein associated with transcriptional elongation complex, possesses histone chaperone activity, and is implicated in recruiti
Externí odkaz:
https://doaj.org/article/99e9b6d78c454b4c84831308f316022a
Autor:
Sundarraj Jayakumar, Manthan Patel, Fanny Boulet, Hadicha Aziz, Greg N. Brooke, Hemanth Tummala, Madapura M. Pradeepa
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/05c0080a04554c67bd978f760c5ee5f7
Autor:
Rana A. Alghamdi, Marino Exposito-Rodriguez, Philip M. Mullineaux, Greg N. Brooke, Philippe P. Laissue
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Phototoxicity is a significant constraint for live cell fluorescence microscopy. Excessive excitation light intensities change the homeostasis of the observed cells. Erroneous and misleading conclusions may be the problematic consequence of observing
Externí odkaz:
https://doaj.org/article/61ad44d7023f4f91b6baca38bf0b011b
Publikováno v:
Viruses, Vol 14, Iss 12, p 2728 (2022)
COVID-19, caused by the severe acute respiratory syndrome coronavirus 2 (SARS CoV-2), is estimated to have caused over 6.5 million deaths worldwide. The emergence of fast-evolving SARS-CoV-2 variants of concern alongside increased transmissibility an
Externí odkaz:
https://doaj.org/article/3fd1438e5ea347ad8ef80292df255ebe
Publikováno v:
F1000Research, Vol 5 (2016)
Prostate cancer is a leading cause of cancer-related death in Western men. Our understanding of the genetic alterations associated with disease predisposition, development, progression, and therapy response is rapidly improving, at least in part, owi
Externí odkaz:
https://doaj.org/article/6d9e01f9ea594b72ab65729989aa7e39
Autor:
Divya R. Jacob, Wilfried M. Guiblet, Hulkar Mamayusupova, Mariya Shtumpf, Luminita Ruje, Isabella Ciuta, Svetlana Gretton, Clark Correa, Emily Dellow, Shivam P. Agrawal, Navid Shafiei, Anastasija Drobysevskaja, Chris M. Armstrong, Jonathan D. G. Lam, Yevhen Vainshtein, Christopher T. Clarkson, Graeme J. Thorn, Kai Sohn, Madapura M. Pradeepa, Sankaran Chandrasekharan, Greg N. Brooke, Elena Klenova, Victor B. Zhurkin, Vladimir B. Teif
Nucleosome repositioning in cancer highlights changes of many aspects of genome organisation and regulation. Understanding it is important both from the fundamental point of view and for medical diagnostics based on cell-free DNA (cfDNA), which origi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ceb9a7b99a207b1579730070281e6ea4
https://doi.org/10.1101/2023.04.17.537031
https://doi.org/10.1101/2023.04.17.537031
Autor:
Charlotte L. Bevan, Marjorie M. Walker, Jonathan Waxman, Robin Wait, Sue M. Powell, Simon C. Gamble, Bradley Spencer-Dene, Craig N. Robson, Stuart R. McCracken, Luke Gaughan, David J. Mann, D. Alwyn Dart, Rachel L. Culley, Greg N. Brooke
Supplementary Figures 1-6, Table 1 from FUS/TLS Is a Novel Mediator of Androgen-Dependent Cell-Cycle Progression and Prostate Cancer Growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61fe951f1375f2eebf0e91b4d13e45f1
https://doi.org/10.1158/0008-5472.22388270.v1
https://doi.org/10.1158/0008-5472.22388270.v1
Publikováno v:
NAR Genomics and Bioinformatics. 5
DNAzymes are short pieces of DNA with catalytic activity, capable of cleaving RNA. DNAzymes have multiple applications as biosensors and in therapeutics. The high specificity and low toxicity of these molecules make them particularly suitable as ther
Publikováno v:
Essays in Biochemistry
COVID-19 symptoms and mortality are largely due to its devastating effects in the lungs. The disease is caused by the SARS (Severe Acute Respiratory Syndrome)-CoV-2 coronavirus, which requires host cell proteins such as ACE2 (angiotensin-converting e