Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Greg Malnassy"'
Autor:
Greg Malnassy, Claudia R. Keating, Shaimaa Gad, Bryan Bridgeman, Aldeb Perera, Wei Hou, Scott J. Cotler, Xianzhong Ding, Mashkoor Choudhry, Zhaoli Sun, Anthony J. Koleske, Wei Qiu
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 16, Iss 5, Pp 685-709 (2023)
Background & Aims: Alcohol-associated liver disease (ALD) represents a spectrum of alcohol use-related liver diseases. Outside of alcohol abstinence, there are currently no Food and Drug Administration–approved treatments for advanced ALD, necessit
Externí odkaz:
https://doaj.org/article/5f68821b84b34b34841dd8c2d00f4bab
Autor:
Wei Hou, Bryan Bridgeman, Greg Malnassy, Xianzhong Ding, Scott J. Cotler, Asha Dhanarajan, Wei Qiu
Publikováno v:
Hepatology Communications, Vol 6, Iss 7, Pp 1786-1802 (2022)
Abstract Lenvatinib is a multikinase inhibitor approved as a first‐line therapy for advanced hepatocellular carcinoma (HCC). However, the development of drug resistance is common, and the underlying mechanisms governing this resistance are largely
Externí odkaz:
https://doaj.org/article/16310e177c80497aa4238e32d1c19f13
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Hepatocellular carcinoma (HCC) is a highly lethal and complex malignancy strongly influenced by the surrounding tumor microenvironment. The HCC microenvironment comprises hepatic stellate cells (HSCs), tumor-associated macrophages (TAMs), stromal and
Externí odkaz:
https://doaj.org/article/f6ea3b0ca51e47e9964bd8ada98307d8
Autor:
Hongtao Liu, Jeffrey L. Johnson, Greg Koval, Greg Malnassy, Dorie Sher, Lloyd E. Damon, Eric D. Hsi, Donna Marie Bucci, Charles A. Linker, Bruce D. Cheson, Wendy Stock
Publikováno v:
Haematologica, Vol 97, Iss 4 (2012)
Background In the present study, the prognostic impact of minimal residual disease during treatment on time to progression and overall survival was analyzed prospectively in patients with mantle cell lymphoma treated on the Cancer and Leukemia Group
Externí odkaz:
https://doaj.org/article/46ee2e7e8efa4009af837fc70eaeb941
Autor:
John C. Grecula, Michaela Liedtke, Kristina Laumann, Guido Marcucci, Richard A. Larson, Wendy Stock, Noreen Fulton, Mark R. Litzow, Selina M. Luger, Martin S. Tallman, Jeffrey A. Bogart, Greg Malnassy, Krzysztof Mrózek, Richard Stone, Frederick R. Appelbaum, Matthew C. Foster, Edy Parker, Anjali S. Advani, Ben L. Sanford, Jun Yin, Charles G. Mullighan, Susan Geyer, Elisabeth Paietta, Richard C. Harvey, Harry P. Erba, Clara D. Bloomfield, Cheryl L. Willman, David F. Claxton
Publikováno v:
Blood. 133:1548-1559
Retrospective studies have suggested that older adolescents and young adults (AYAs) with acute lymphoblastic leukemia (ALL) have better survival rates when treated using a pediatric ALL regimen administered by pediatric treatment teams. To address th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74b4ade97c3f128792b9ad2f40df8efc
https://doi.org/10.1182/blood-2018-10-881961
https://doi.org/10.1182/blood-2018-10-881961
Autor:
Houda Alachkar, Yusuke Nakamura, Clara D. Bloomfield, Richard A. Larson, Ben L. Sanford, Wendy Stock, Noreen Fulton, Martin Mutonga, Guido Marcucci, Greg Malnassy
Publikováno v:
The pharmacogenomics journal
Asparaginase, which depletes asparagine and glutamine, activates amino-acid stress response. Oxidative stress mediated by excessive reactive oxygen species (ROS) causes enhanced mitochondrial permeabilization and subsequent cell apoptosis and is cons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdba2e02e5a240e4be7f77447c4f4541
http://europepmc.org/articles/PMC5089920
http://europepmc.org/articles/PMC5089920
Autor:
Peter D. Emanuel, Martha Wadleigh, Jeffrey H. Lipton, Jerald P. Radich, Brian J. Druker, Kenneth J. Kopecky, Greg Malnassy, Wendy Stock, Martin S. Tallman, A. Robert Turner, Elisabeth Paietta, Frederick R. Appelbaum, Richard A. Larson, Michael W. Deininger, Suzanne Kamel-Reid
Publikováno v:
Blood. 120(19)
Tyrosine kinase inhibitor therapy with imatinib (IM), dasatinib (DAS), or nilotinib is very effective in chronic-phase chronic myeloid leukemia. Two hundred fifty-three patients with newly diagnosed chronic-phase chronic myeloid leukemia were randomi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::158111db5e49741eb327adbb281345fb
https://pubmed.ncbi.nlm.nih.gov/23144157
https://pubmed.ncbi.nlm.nih.gov/23144157
Autor:
Wendy Stock, Eric D. Hsi, Donna Bucci, Greg Koval, Dorie Sher, Jeffrey L. Johnson, Hongtao Liu, Greg Malnassy, Bruce D. Cheson, Lloyd E. Damon, Charles A. Linker
Publikováno v:
Haematologica. 97(4)
Background In the present study, the prognostic impact of minimal residual disease during treatment on time to progression and overall survival was analyzed prospectively in patients with mantle cell lymphoma treated on the Cancer and Leukemia Group
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cad2a1f99ed4b0b3fdd5f4dcf41f0fe9
https://pubmed.ncbi.nlm.nih.gov/22102709
https://pubmed.ncbi.nlm.nih.gov/22102709
Autor:
Elisabeth Paietta, Selina M. Luger, Michaela Liedtke, David F. Claxton, Kristina Laumann, Matthew C. Foster, Edy Parker, Richard Stone, Susan Geyer, Frederick R. Appelbaum, Harry P. Erba, Greg Malnassy, Wendy Stock, Richard C. Harvey, Guido Marcucci, Mark R. Litzow, Anjali S. Advani, Cheryl L. Willman, Martin S. Tallman, Richard A. Larson, Ben L. Sanford, Charles G. Mullighan
Publikováno v:
Blood. 124:796-796
Background: Retrospective analyses have demonstrated significantly improved survival for AYA ALL patients (pts) aged 16-21 years (yrs) when treated on pediatric versus adult U.S. NCI Cooperative group regimens where 2-yr event-free survivals (EFS) ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::534ddc7a3dbfacda7bd5156504b10d9a
https://doi.org/10.1182/blood.v124.21.796.796
https://doi.org/10.1182/blood.v124.21.796.796
Autor:
Charles A. Linker, Lloyd E. Damon, Dorie Sher, Greg Malnassy, Hongtao Liu, Jeffrey L. Johnson, Greg Koval, Wendy Stock, Pamela Ihonor
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 11:S130-S131
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3164f15974b86d82daaa18edf34ab953
https://doi.org/10.1016/j.clml.2011.05.026
https://doi.org/10.1016/j.clml.2011.05.026