Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Greg M. Harris"'
Autor:
Jennifer A. Westphal, Andrew E. Bryan, Maksym Krutko, Leyla Esfandiari, Stacey C. Schutte, Greg M. Harris
Publikováno v:
Biomimetics, Vol 9, Iss 1, p 2 (2023)
In this work, electrospun polyvinylidene-trifluoroethylene (PVDF-TrFE) was utilized for its biocompatibility, mechanics, and piezoelectric properties to promote Schwann cell (SC) elongation and sensory neuron (SN) extension. PVDF-TrFE electrospun sca
Externí odkaz:
https://doaj.org/article/673a3fc4420f4bc6b33c558d107d5421
Publikováno v:
European Journal of Cell Biology, Vol 101, Iss 4, Pp 151277- (2022)
Peripheral nervous system (PNS) injuries are an ongoing health care concern. While autografts and allografts are regarded as the current clinical standard for traumatic injury, there are inherent limitations that suggest alternative remedies should b
Externí odkaz:
https://doaj.org/article/335a4d2d994a486c81b1aa10b3920d53
Publikováno v:
Bioengineering, Vol 7, Iss 3, p 102 (2020)
Bioactive surfaces and materials have displayed great potential in a variety of tissue engineering applications but often struggle to completely emulate complex bodily systems. The extracellular matrix (ECM) is a crucial, bioactive component in all t
Externí odkaz:
https://doaj.org/article/35b842d72be2438e93fb82ae2375b006
Publikováno v:
PLoS ONE, Vol 9, Iss 1 (2014)
Externí odkaz:
https://doaj.org/article/1a7e02e06a384e678ede2ea42391fdce
Autor:
Jacob A. Orkwis, Ann K. Wolf, Zachary J. Mularczyk, Andrew E. Bryan, Corinne S. Smith, Ryan Brown, Maksym Krutko, Adam McCann, Ryan M. Collar, Leyla Esfandiari, Greg M. Harris
Publikováno v:
Biomaterials advances. 140
Traumatic nerve injuries have limited success in achieving full functional recovery, with current clinical solutions often including implementation of nerve grafts or the use of nerve conduits to guide damaged axons across injury gaps. In search of a
Autor:
Kelly Lim, Jeffrey W. Chen, Joshua A. Spechler, Greg M. Harris, Jean E. Schwarzbauer, Stephen B. Bandini, Craig B. Arnold, Jeffrey Schwartz, Romain Fardel
Publikováno v:
ACS Applied Materials & Interfaces. 11:15411-15416
A two-step synthesis is described for activating the surface of a fully hydrated hydrogel that is of interest as a possible scaffold for neural regeneration devices. The first step exploits the water content of the hydrogel and the hydrophobicity of
Publikováno v:
Journal of Visualized Experiments.
Traumatic peripheral nervous system (PNS) injuries currently lack suitable treatments to regain full functional recovery. Schwann cells (SCs), as the major glial cells of the PNS, play a vital role in promoting PNS regeneration by dedifferentiating i
Autor:
Lynn W. Enquist, Greg M. Harris, Nicolas N. Madigan, Karen Z. Lancaster, Jeffrey Schwartz, Jean E. Schwarzbauer, Anthony J. Windebank
Publikováno v:
Matrix Biology. :176-189
Spinal cord and peripheral nerve injuries require the regeneration of nerve fibers across the lesion site for successful recovery. Providing guidance cues and soluble factors to promote neurite outgrowth and cell survival can enhance repair. The extr
Publikováno v:
Journal of tissue engineering and regenerative medicineREFERENCES. 14(2)
Peripheral nerve injuries require a complex set of signals from cells, macrophages, and the extracellular matrix (ECM) to induce regeneration across injury sites and achieve functional recovery. Schwann cells (SCs), the major glial cell in the periph
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 9
International Journal of Molecular Sciences, Vol 22, Iss 4821, p 4821 (2021)
Volume 22
Issue 9
International Journal of Molecular Sciences, Vol 22, Iss 4821, p 4821 (2021)
Schwann cells (SCs) are a highly plastic cell type capable of undergoing phenotypic changes following injury or disease. SCs are able to upregulate genes associated with nerve regeneration and ultimately achieve functional recovery. During the regene