Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Greg L. Olsen"'
Publikováno v:
Journal of molecular biology. 434(16)
The microRNAs are non-coding RNAs which post-transcriptionally regulate the expression of many eukaryotic genes, and whose dysregulation is a driver of human disease. Here we report the discovery of a very slow (0.1 s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94d2d35dca0de592a6dd61ba370ba10a
https://pubmed.ncbi.nlm.nih.gov/35752213
https://pubmed.ncbi.nlm.nih.gov/35752213
Autor:
Greg L. Olsen, Hartmut Oschkinat, Akiva Feintuch, Fabien Aussenac, Ümit Akbey, Lucio Frydman, Christian O. Bretschneider
Publikováno v:
Bretschneider, C O, Akbey, Ü, Aussenac, F, Olsen, G L, Feintuch, A, Oschkinat, H & Frydman, L 2016, ' Cover Picture : On The Potential of Dynamic Nuclear Polarization Enhanced Diamonds in Solid-State and Dissolution 13 C NMR Spectroscopy (ChemPhysChem 17/2016) ', ChemPhysChem, vol. 17, no. 17, pp. 2609 . https://doi.org/10.1002/cphc.201600878
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::316ede0c570810501645c709b6a60b05
https://pure.au.dk/portal/da/publications/cover-picture(7955d126-3682-4666-8063-e7e59195fd19).html
https://pure.au.dk/portal/da/publications/cover-picture(7955d126-3682-4666-8063-e7e59195fd19).html
Autor:
Greg L. Olsen, Akiva Feintuch, Hartmut Oschkinat, Ümit Akbey, Lucio Frydman, Christian O. Bretschneider, Fabien Aussenac
Publikováno v:
Bretschneider, C O, Akbey, Ü, Aussenac, F, Olsen, G L, Feintuch, A, Oschkinat, H & Frydman, L 2016, ' On The Potential of Dynamic Nuclear Polarization Enhanced Diamonds in Solid-State and Dissolution (13) C NMR Spectroscopy ', ChemPhysChem, vol. 17, no. 17, pp. 2691-2701 . https://doi.org/10.1002/cphc.201600301
Dynamic nuclear polarization (DNP) is a versatile option to improve the sensitivity of NMR and MRI. This versatility has elicited interest for overcoming potential limitations of these techniques, including the achievement of solid-state polarization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4a08d63285f0b8118d1924baaec0427
https://pure.au.dk/portal/da/publications/on-the-potential-of-dynamic-nuclear-polarization-enhanced-diamonds-in-solidstate-and-dissolution-13-c-nmr-spectroscopy(67dd673e-1ebb-4b53-b1ec-bd1debd7612e).html
https://pure.au.dk/portal/da/publications/on-the-potential-of-dynamic-nuclear-polarization-enhanced-diamonds-in-solidstate-and-dissolution-13-c-nmr-spectroscopy(67dd673e-1ebb-4b53-b1ec-bd1debd7612e).html
Publikováno v:
Journal of magnetic resonance (San Diego, Calif. : 1997). 264
A recent study explored the use of hyperpolarized water, to enhance the sensitivity of nuclei in biomolecules thanks to rapid proton exchanges with labile amide backbone and sidechain groups. Further optimizations of this approach have now allowed us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6442fb641ab6aae3b9feadbc4f4a8e07
https://pubmed.ncbi.nlm.nih.gov/26920830
https://pubmed.ncbi.nlm.nih.gov/26920830
Publikováno v:
Journal of the American Chemical Society. 132:303-308
Many RNAs undergo large conformational changes in response to the binding of proteins and small molecules. However, when RNA functional dynamics occur in the nanosecond-microsecond time scale, they become invisible to traditional solution NMR relaxat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19bdf206c049e989dd5151c3d8ac7247
https://doi.org/10.1021/ja907515s
https://doi.org/10.1021/ja907515s
Publikováno v:
Journal of Biomolecular NMR. 45:133-142
The essential role played by local and collective motions in RNA function has led to a growing interest in the characterization of RNA dynamics. Recent investigations have revealed that even relatively simple RNAs experience complex motions over mult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c35ad3e23ba70c5683afd3accc01f4c
https://doi.org/10.1007/s10858-009-9355-6
https://doi.org/10.1007/s10858-009-9355-6
Autor:
Greg L. Olsen, Gabriele Varani, Thomas E. Edwards, Pritilekha Deka, Gary P. Drobny, Snorri Th. Sigurdsson
Publikováno v:
Nucleic Acids Research
Complexes of the HIV transactivation response element (TAR) RNA with the viral regulatory protein tat are of special interest due in particular to the plasticity of the RNA at this binding site and to the potential for therapeutic targeting of the in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::769cb6401a780498ee2f2a3244edae81
http://europepmc.org/articles/PMC1151589
http://europepmc.org/articles/PMC1151589
Publikováno v:
Nucleic Acids Research. 31:5084-5089
We have performed solid-state 31P-19F REDOR nuclear magnetic resonance (NMR) experiments to monitor changes in minor groove width of the oligonucleotide d(CGCAAA2'FUTGGC)*d(GCCAAT(pS)TT GCG) (A3T2) upon binding of the drug distamycin A at different s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99b6d33bc50b1a3c2c580c5f15f15abc
https://doi.org/10.1093/nar/gkg720
https://doi.org/10.1093/nar/gkg720
Autor:
Greg L. Olsen, Gabriele Varani, Zahra Shajani, Dorothy C. Echodu, Gary P. Drobny, Michael F. Bardaro
Publikováno v:
Journal of the American Chemical Society. 130(10)
Solution and solid-state NMR measurements were used together to examine motion in three sites in the HIV-1 TAR RNA. We wished to investigate the dynamics facilitating the conformational rearrangements the TAR RNA must undergo for Tat binding and in p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fadda7c51a2d209d9e3b2e830d62f659
https://pubmed.ncbi.nlm.nih.gov/18275190
https://pubmed.ncbi.nlm.nih.gov/18275190