Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Greg J, Hermann"'
Autor:
Caitlin Morris, Olivia K Foster, Simran Handa, Kimberly Peloza, Laura Voss, Hannah Somhegyi, Youli Jian, My Van Vo, Marie Harp, Fiona M Rambo, Chonglin Yang, Greg J Hermann
Publikováno v:
PLoS Genetics, Vol 14, Iss 11, p e1007772 (2018)
Cell type-specific modifications of conventional endosomal trafficking pathways lead to the formation of lysosome-related organelles (LROs). C. elegans gut granules are intestinally restricted LROs that coexist with conventional degradative lysosomes
Externí odkaz:
https://doaj.org/article/5e310e972da646db91a3cc30366a59b0
Autor:
Victoria Eichten, Kimberly Peloza, Greg J. Hermann, Olivia K. Foster, Marie Harp, Logan Harper, Caitlin Morris, James N Brandt, Simran Handa, Brian King, Laura Voss, Fiona M. Rambo, Amanda Maxfield, Sierra Lavoy
Publikováno v:
Genetics. 214:419-445
ABC transporters couple ATP hydrolysis to the transport of substrates across cellular membranes. This protein superfamily has diverse activities resulting from differences in their cargo and subcellular localization. Our work investigates the role of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8015e4b6e583bca3bd7527e3a642373c
https://doi.org/10.1534/genetics.119.302900
https://doi.org/10.1534/genetics.119.302900
Autor:
Luca Sax, Victoria Eichten, Jackson R. Thein, Katelyn Nicholson, Lali Guevara-Hernandez, Matthew L. White, Greg J. Hermann, Fiona M. Rambo, Lydia Fairchild, Laurence Seabrook, James N Brandt, Danielia Lewis, Logan Harper, Laura Voss
Publikováno v:
Dev Biol
While the epithelial cell cortex displays profound asymmetries in protein distribution and morphology along the apico-basal axis, the extent to which the cytoplasm is similarly polarized within epithelial cells remains relatively unexplored. We show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc066f2b6a06952369fb8a0aea6896f1
https://pubmed.ncbi.nlm.nih.gov/34597675
https://pubmed.ncbi.nlm.nih.gov/34597675
Autor:
Greg J Hermann, Emily Scavarda, Allison M Weis, Daniel S Saxton, Laura L Thomas, Rebecca Salesky, Hannah Somhegyi, Thomas P Curtin, Alec Barrett, Olivia K Foster, Annalise Vine, Katherine Erlich, Elizabeth Kwan, Beverley M Rabbitts, Kaila Warren
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43043 (2012)
The human disease Hermansky-Pudlak syndrome results from defective biogenesis of lysosome-related organelles (LROs) and can be caused by mutations in subunits of the BLOC-1 complex. Here we show that C. elegans glo-2 and snpn-1, despite relatively lo
Externí odkaz:
https://doaj.org/article/60d7b6b7cb714b1da186bfbe8d8edcaa
Autor:
Laura, Voss, Olivia K, Foster, Logan, Harper, Caitlin, Morris, Sierra, Lavoy, James N, Brandt, Kimberly, Peloza, Simran, Handa, Amanda, Maxfield, Marie, Harp, Brian, King, Victoria, Eichten, Fiona M, Rambo, Greg J, Hermann
Publikováno v:
Genetics
ABC transporters couple ATP hydrolysis to the transport of substrates across cellular membranes. This protein superfamily has diverse activities resulting from differences in their cargo and subcellular localization. Our work investigates the role of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a8ad44a673172919ed246b54bc43e8ea
https://pubmed.ncbi.nlm.nih.gov/31848222
https://pubmed.ncbi.nlm.nih.gov/31848222
Autor:
Natalie E. Cain, Daniel A. Starr, James N Brandt, Greg J. Hermann, Leslie A Herrera, Heidi N. Fridolfsson
Publikováno v:
The LINC Complex ISBN: 9781493986903
Studying nuclear positioning in developing tissues of the model nematode Caenorhabditis elegans greatly contributed to the discovery of SUN and KASH proteins and the formation of the LINC model. Such studies continue to make important contributions i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6539beef33da1d3bca10b63740f4cd43
https://doi.org/10.1007/978-1-4939-8691-0_13
https://doi.org/10.1007/978-1-4939-8691-0_13
Autor:
Greg J. Hermann, Hannah Somhegyi, Thomas P. Curtin, Daniel S. Saxton, Annalise Vine, Rebecca Salesky, Olivia K. Foster, Jared L. Delahaye
Publikováno v:
Molecular Biology of the Cell
This work presents a systematic analysis of how VPS-C/HOPS, CCZ-1/SAND-1, and RAB-7, which have well-defined roles in lysosome formation, act in the biogenesis of Caenorhabditis elegans lysosome-related organelles. It identifies key molecular similar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28544f457b4c1283fa19634bf10b9c95
https://doi.org/10.1091/mbc.e13-09-0521
https://doi.org/10.1091/mbc.e13-09-0521
Autor:
Madeline Cole, Steven Levitte, Brian King, Micah Depper, Rebecca Salesky, Sage Coe Smith, Greg J. Hermann
Publikováno v:
FEBS Journal. 277:1420-1439
Gut granules are cell type-specific lysosome-related organelles found within the intestinal cells of Caenorhabditis elegans. To investigate the regulation of lysosome-related organelle size, we screened for C. elegans mutants with substantially enlar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f0b7df2e74b93257b9d4c0a92d6f1a8
https://doi.org/10.1111/j.1742-4658.2010.07573.x
https://doi.org/10.1111/j.1742-4658.2010.07573.x
Autor:
Lena K. Schroeder, Brian King, Andrea L. Lawrenson, Greg J. Hermann, Aaron M. Kershner, Erin Currie
Publikováno v:
Genetics. 177:1569-1582
Caenorhabditis elegans gut granules are lysosome-related organelles with birefringent contents. mrp-4, which encodes an ATP-binding cassette (ABC) transporter homologous to mammalian multidrug resistance proteins, functions in the formation of gut gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b803afd4231cf8e125cbd608bc3c4ae
https://doi.org/10.1534/genetics.107.080689
https://doi.org/10.1534/genetics.107.080689
Autor:
Greg J. Hermann, Jennifer L. Watts, Susan Kremer, Erin Currie, Lena K. Schroeder, Andrea L. Lawrenson, Elizabeth Kwan, Maxwell Kramer
Publikováno v:
Molecular Biology of the Cell. 18:995-1008
Caenorhabditis elegans gut granules are intestine specific lysosome-related organelles with birefringent and autofluorescent contents. We identified pgp-2, which encodes an ABC transporter, in screens for genes required for the proper formation of gu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4c25a5368d81ad5099ff98cf029e07b
https://doi.org/10.1091/mbc.e06-08-0685
https://doi.org/10.1091/mbc.e06-08-0685