Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Greg Haug"'
Autor:
Surajit Dey, Wenying Lu, Greg Haug, Collin Chia, Josie Larby, Heinrich C. Weber, Archana Vijay Gaikwad, Prem Bhattarai, Affan Mahmood Shahzad, Prabuddha S. Pathinayake, Peter A. B. Wark, Mathew Suji Eapen, Sukhwinder Singh Sohal
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-21 (2023)
Abstract Background Although asthma and chronic obstructive pulmonary disease (COPD) are two distinct chronic airway inflammatory diseases, they often co-exist in a patient and the condition is referred to as asthma-COPD overlap (ACO). Lack of eviden
Externí odkaz:
https://doaj.org/article/5e348fad49dd4876b16753136037991c
Autor:
Samuel James Brake, Wenying Lu, Collin Chia, Greg Haug, Josie Larby, Ashutosh Hardikar, Gurpreet K. Singhera, Tillie L. Hackett, Mathew Suji Eapen, Sukhwinder Singh Sohal
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundCOPD is a common disease characterized by respiratory airflow obstruction. TGF-β1 and SMAD pathway is believed to play a role in COPD pathogenesis by driving epithelial mesenchymal transition (EMT).MethodsWe investigated TGF-β1 signalling
Externí odkaz:
https://doaj.org/article/1785ac62c9de46619da72af6e7aa262d
Autor:
Archana Vijay Gaikwad, Wenying Lu, Surajit Dey, Prem Bhattarai, Greg Haug, Josie Larby, Collin Chia, Jade Jaffar, Glen Westall, Gurpreet Kaur Singhera, Tillie-Louise Hackett, Mathew Suji Eapen, Sukhwinder Singh Sohal
Publikováno v:
ERJ Open Research, Vol 9, Iss 2 (2023)
Background We have previously reported arterial remodelling in patients with idiopathic pulmonary fibrosis (IPF) and suggested that endothelial-to-mesenchymal transition (EndMT) might be central to these changes. This study aims to provide evidence f
Externí odkaz:
https://doaj.org/article/b49ad27c47024587a61b641213c727bf
Autor:
Prem Bhattarai, Wenying Lu, Archana Vijay Gaikwad, Surajit Dey, Collin Chia, Josie Larby, Greg Haug, Ashutosh Hardikar, Andrew Williams, Gurpreet Kaur Singhera, Tillie-Louise Hackett, Mathew Suji Eapen, Sukhwinder Singh Sohal
Publikováno v:
ERJ Open Research, Vol 8, Iss 4 (2022)
Introduction Pulmonary vascular remodelling in chronic obstructive pulmonary disease (COPD) has detrimental consequences for lung physiology. The aim of our study was to provide a comprehensive size-based morphometric quantification of pulmonary arte
Externí odkaz:
https://doaj.org/article/52836600fe7a4a06ad575edb484c53ab
Autor:
Archana Vijay Gaikwad, Wenying Lu, Surajit Dey, Prem Bhattarai, Collin Chia, Josie Larby, Greg Haug, Stephen Myers, Jade Jaffar, Glen Westall, Gurpreet Kaur Singhera, Tillie-Louise Hackett, James Markos, Mathew Suji Eapen, Sukhwinder Singh Sohal
Publikováno v:
ERJ Open Research, Vol 8, Iss 1 (2022)
Background Idiopathic pulmonary fibrosis (IPF) is a progressive, irreversible fibrotic interstitial lung disease. We performed size-based quantitation of pulmonary arterial remodelling in IPF and examined the role of endothelial-to-mesenchymal transi
Externí odkaz:
https://doaj.org/article/cf0b599125c9433998a32829faa4515e
Autor:
Sanjay S Gautam, Micheál Mac Aogáin, Louise A Cooley, Greg Haug, Janet A Fyfe, Maria Globan, Ronan F O'Toole
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192351 (2018)
The origin and spread of tuberculosis (TB) in Tasmania and the types of strains of Mycobacterium tuberculosis complex (MTBC) present in the population are largely unknown.The aim of this study was to perform the first genomic analysis of MTBC isolate
Externí odkaz:
https://doaj.org/article/805bd701561b497da69189056900206b
Autor:
Wenying Lu, Affan Mahmood Shahzad, Josie Larby, Maddison Waters, Melinda Wilson, Jade Jaffar, Glen Westall, Darren Sutherland, Greg Haug, Tillie L. Hackett, Sukhwinder Singh Sohal
Publikováno v:
Pulmonology, Vol 31, Iss 1 (2025)
Externí odkaz:
https://doaj.org/article/8a0a5401285e4d7489a1f0342bb20cdc
Autor:
Surajit Dey, Wenying Lu, Heinrich C. Weber, Sally Young, Josie Larby, Collin Chia, Greg Haug, Samuel James Brake, Stephen Myers, Archana Vijay Gaikwad, Prem Bhattarai, Prabuddha S. Pathinayake, Peter A. B. Wark, Mathew Suji Eapen, Sukhwinder Singh Sohal
Publikováno v:
American journal of physiology. Lung cellular and molecular physiology. 323(4)
Management of patients with asthma COPD overlap (ACO) is clinically challenging due to insufficient evidence of pathological changes in these patients. In this cross-sectional study, we evaluated airway remodeling in endobronchial biopsies from a tot
Autor:
Mathew Suji Eapen, Collin Chia, Greg Haug, Purva Asrani, Sukhwinder Singh Sohal, Heinrich C. Weber, Imtaiyaz Hassan
Publikováno v:
Expert Review of Respiratory Medicine
COVID-19 is a recent emerging pandemic whose prognosis is still unclear. Diagnostic tools are the main players that not only indicate a possible infection but can further restrict the transmission and can determine the extent to which disease progres
Autor:
Collin Chia, Sukhwinder Singh Sohal, James Markos, Allan R. Glanville, Mathew Suji Eapen, Stephen Myers, Archana Vijay Gaikwad, Kielan Darcy McAlinden, Greg Haug, Josie Larby, Surajit Dey
Publikováno v:
Expert Review of Respiratory Medicine. 14:1027-1043
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and irreversible fibrotic disease associated with respiratory failure. The disease remains idiopathic, but repeated alveolar epithelium injury, disruption of alveolar-capillary integrity,