Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Greg H. Enders"'
Autor:
Emma E. Furth, Karen S. Gustafson, Charlotte Y. Dai, Steven L. Gibson, Paul Menard-Katcher, Tina Chen, Jim Koh, Greg H. Enders
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 8, Iss 6, Pp 429-436 (2006)
p16INK4a is a major tumor-suppressor protein, but its regulation and settings of fuction remain poorly understood. To explore the notion that p16 is induced in vivo in response to replicative stress, we examined p16 expression in tissues from human u
Externí odkaz:
https://doaj.org/article/d9f9ddbb80d84af1adfff90997b74486
Autor:
Greg H. Enders, Hemant Goyal, Umesha Boregowda, Milos Babic, Bojana Milekic, Mladen Jecmenica, Mark M. Aloysius, Abhilash Perisetti, Anurag Bajaj, Pardeep Bansal, Mahesh Cheryala
Publikováno v:
Annals of Gastroenterology
Background Direct-acting oral anticoagulants (DOACs) are increasingly used, with studies showing a lower risk of gastrointestinal bleeding (GIB), but overall data for GIB risk remains debatable. The objective was to assess non-fatal and fatal GIB ris
Autor:
Nirav Thosani, Abhilash Perisetti, Mark M. Aloysius, Hemant Goyal, Aman Ali, Sonali Sachdeva, Benjamin Tharian, Greg H. Enders, Syed Ali Amir Sherazi
Publikováno v:
American Journal of Gastroenterology. 116:S298-S298
Publikováno v:
American Journal of Gastroenterology. 116:S1286-S1286
Autor:
Greg H. Enders, Nigel B. Jamieson, Karin A. Oien, David M. Nelson, Owen J. Sansom, Rugang Zhang, Peter D. Adams, Jeff S. Pawlikowski, Colin J. McKay, Brendan Doyle, Tony McBryan, Jennifer P. Morton, Alyssa L. Kennedy, Indrani Manoharan
Mutations in both RAS and the PTEN/PIK3CA/AKT signaling module are found in the same human tumors. PIK3CA and AKT are downstream effectors of RAS, and the selective advantage conferred by mutation of two genes in the same pathway is unclear. Based on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48387dede6d08baef5646003f6e698ca
https://ora.ox.ac.uk/objects/uuid:12829cd0-a1f0-4a4f-b471-0ec7737e0e9f
https://ora.ox.ac.uk/objects/uuid:12829cd0-a1f0-4a4f-b471-0ec7737e0e9f
Autor:
Greg H. Enders, Mladen Jecmenica, Pardeep Bansal, Rupak Desai, Hemant Goyal, Mark M. Aloysius
Publikováno v:
International journal of colorectal disease. 34(9)
Study national hospitalization trends for colorectal cancer in patients younger than 50 years of age. Patients under age 50 years hospitalized for colorectal cancer were studied using the national inpatient sample databases (2010–2014), using valid
Publikováno v:
Aging Cell
The cyclin-dependent kinase (Cdk) inhibitor p16(Ink4a) (p16) is a canonical mediator of cellular senescence and accumulates in aging tissues, where it constrains proliferation of some progenitor cells. However, whether p16 induction in tissues is suf
Autor:
Greg H. Enders
Publikováno v:
Genes & Cancer. 3:614-618
Cyclin-dependent kinases (Cdks) drive cell cycle progression in all eukaryotes. Yeasts have a single major Cdk that mediates distinct cell cycle transitions via association with different cyclins. The closest homolog in mammals, Cdk1, drives mitosis.
Autor:
Joel E. Richter, Harry S. Cooper, Tina Chen, Gary W. Falk, Sam Litwin, Greg H. Enders, Andres J. Klein-Szanto, Amelie Boquoi, Urs von Holzen, David S. Weinberg
Publikováno v:
Translational Oncology. 3(1):33-42
Barrett esophagus is an epithelial metaplasia that predisposes to adenocarcinoma. Better markers of cancer risk are urgently needed to identify those patients who are likely to benefit most from emerging methods of endoscopic ablation. Disease progre
Publikováno v:
Molecular and Cellular Biology. 30:116-130
Received 10 December 2008/Returned for modification 11 January 2009/Accepted 10 October 2009 Sophisticated models for the regulation of mitotic entry are lacking for human cells. Inactivating human cyclin A/Cdk2 complexes through diverse approaches d