Sociodemographic and clinical factors associated with receipt of biomarker testing in patients with metastatic colorectal cancer

Autor: Sarah C. Markt, Benjamin D. Booker, Wyatt Bensken, Nicholas K. Schiltz, Fredrick R. Schumacher, Johnie Rose, Greg Cooper, J. Eva Selfridge, Siran M. Koroukian

Publikováno v: Cancer Medicine, Vol 12, Iss 2, Pp 1850-1859 (2023)

Abstract Background Standard clinical practice and national guidelines dictate somatic testing of metastatic colorectal cancer (mCRC) tumors to guide appropriate therapy; however, previous studies suggest that not all patients are tested. The objecti

Externí odkaz: https://doaj.org/article/c431cef72dda406ba4f807b405e1bec0

Learning Adjustment Sets from Observational and Limited Experimental Data

Autor: Sofia Triantafillou, Greg Cooper

Publikováno v: Proceedings of the AAAI Conference on Artificial Intelligence. 35:9940-9948

Estimating causal effects from observational data is not always possible due to confounding. Identifying a set of appropriate covariates (adjustment set) and adjusting for their influence can remove confounding bias; however, such a set is often not

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e7d5a03f71592098066f78784b5b0c3c
https://doi.org/10.1609/aaai.v35i11.17194

Resolving QC failures

Autor: W Greg, Cooper

Publikováno v: MLO: medical laboratory observer. 48(8)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0de2e638d7fc57bccf45e784cd2120b4
https://pubmed.ncbi.nlm.nih.gov/29924547

Acetylcholinesterase Inhibitor Treatment is Associated with Relatively Slow Cognitive Decline in Patients with Alzheimer's Disease and AD + DLB

Autor: Greg Cooper, Peter T. Nelson, Gregory A. Jicha, William R. Markesbery, Richard J. Kryscio, Marta S. Mendiondo, Charles B. Smith, Frederick A. Schmitt, Erin L. Abner

Publikováno v: Journal of Alzheimer's Disease. 16:29-34

Dementia can be caused by different diseases including Alzheimer's disease (AD), dementia with Lewy bodies (DLB), or both (AD + DLB). University of Kentucky AD Center pathologically-diagnosed AD and AD + DLB cases were evaluated who had three or more

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::981118ad80569d8da8092ea1d7eb93ee
https://doi.org/10.3233/jad-2009-0926

Return of genomic results to research participants: the floor, the ceiling, and the choices in between

Autor: Gail P. Jarvik, Laura M. Amendola, Jonathan S. Berg, Kyle Brothers, Ellen W. Clayton, Wendy Chung, Barbara J. Evans, James P. Evans, Stephanie M. Fullerton, Carlos J. Gallego, Nanibaa’ A. Garrison, Stacy W. Gray, Ingrid A. Holm, Iftikhar J. Kullo, Lisa Soleymani Lehmann, Cathy McCarty, Cynthia A. Prows, Heidi L. Rehm, Richard R. Sharp, Joseph Salama, Saskia Sanderson, Sara L. Van Driest, Marc S. Williams, Susan M. Wolf, Wendy A. Wolf, Wylie Burke, John Harley, Melanie Myers, Bahram Namjou, Sander Vinks, John Connolly, Brendan Keating, Glenn Gerhard, Agnes Sundaresan, Gerard Tromp, David Crosslin, Kathy Leppig, Cathy Wicklund, Christopher Chute, John Lynch, Mariza De Andrade, John Heit, Jen McCormick, Murray Brilliant, Terrie Kitchner, Marylyn Ritchie, Erwin Böttinger, Inga Peter, Stephen Persell, Laura Rasmussen-Torvik, Tracy McGregor, Dan Roden, Armand Antommaria, Rosetta Chiavacci, Andy Faucett, David Ledbetter, Janet Williams, Andrea Hartzler, Carolyn R. Rohrer Vitek, Norm Frost, Kadija Ferryman, Carol Horowitz, Rosamond Rhodes, Randi Zinberg, Sharon Aufox, Vivian Pan, Rochelle Long, Erin Ramos, Jackie Odgis, Anastasia Wise, Sara Hull, Jonathan Gitlin, Robert Green, Danielle Metterville, Amy McGuire, Sek Won Kong, Sue Trinidad, David Veenstra, Myra Roche, Debra Skinner, Kelly Raspberry, Julianne O’Daniel, Will Parsons, Christine Eng, Susan Hilsenbeck, Dean Karavite, Laura Conlin, Nancy Spinner, Ian Krantz, Marni Falk, Avni Santani, Elizabeth Dechene, Matthew Dulik, Barbara Bernhardt, Scott Schuetze, Jessica Everett, Michele Caroline Gornick, Ben Wilfond, Holly Tabor, Amy A. Lemke, Sue Richards, Katrina Goddard, Greg Cooper, Kelly East, Greg Barsh, Barbara Koenig, Eliezer Van Allen, Judy Garber, Jeremy Garrett, Ma’n Zawati, Michelle Lewis, Sarah Savage, Maureen Smith, Sameek Roychowdhury, Alice Bailey, Benjamin Berkman, Charlisse Caga Anan, Lucia Hindorff, Carolyn Hutter, Rosalind King, Rongling Li, Nicole Lockhart, Jean McEwen, Derek Scholes, Sheri Schully, Kathie Sun

Publikováno v: American journal of human genetics. 94(6)

As more research studies incorporate next-generation sequencing (including whole-genome or whole-exome sequencing), investigators and institutional review boards face difficult questions regarding which genomic results to return to research participa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42cd5af9f44ff403989325767cb971d8
https://pubmed.ncbi.nlm.nih.gov/24814192