Výsledky vyhledávání - "Greg Contento"

Triple therapy with pravastatin, low molecular weight heparin and low dose aspirin improves placental haemodynamics and pregnancy outcomes in obstetric antiphospholipid syndrome in mice and women through a nitric oxide-dependent mechanism

Autor: Eleftheria, Lefkou, Katerina, Varoudi, Joaquim, Pombo, Aleksandar, Jurisic, Zaklina, Jurisic, Greg, Contento, Guillermina, Girardi

Publikováno v: Biochemical pharmacology. 182

A previous pilot study showed that pravastatin supplementation improved pregnancy outcomes in women with obstetric antiphospholipid syndrome (OAPS) that developed placental insufficiency despite standard of care treatment low molecular weight heparin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8dee7c02c3ed36ff1fb55231de9ac46f
https://pubmed.ncbi.nlm.nih.gov/32926874

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mTORC1 amplifies the ATF4-dependent de novo serine-glycine pathway to supply glycine during TGF-β 1 –induced collagen biosynthesis

Autor: Brintha Selvarajah, Greg Contento, Delphine Guillotin, Ellen J. Forty, Gino Brunori, Adam Taylor, Pascal F. Durrenberger, Andy Blanchard, Matthew Redding, Hannah V. Woodcock, Dimitrios Anastasiou, Riccardo Ronzoni, Ilan Azuelos, Rachel C. Chambers, Manuela Platé, Paul F. Mercer

Publikováno v: Science Signaling. 12

The differentiation of fibroblasts into a transient population of highly activated extracellular matrix (ECM) producing myofibroblasts at sites of tissue injury is critical for normal tissue repair. Excessive myofibroblast accumulation and persistenc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31bd25cfb260d06077c40b5de4c02ae6
https://doi.org/10.1126/scisignal.aav3048

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