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pro vyhledávání: '"Greg Christoph"'
Autor:
David A. Brott, Håkan A.S. Andersson, Jane Stewart, Lorna Ewart, Greg Christoph, Johannes Harleman, Duncan Armstrong, Lewis B. Kinter
Publikováno v:
Toxicology Reports, Vol 1, Iss C, Pp 1202-1212 (2014)
Background: Ticagrelor is an orally available, direct acting and reversible P2Y12 receptor antagonist approved for treatment of acute coronary syndrome. The objectives of these studies were to (1) evaluate the Ticagrelor 2-year rat carcinogenicity bi
Externí odkaz:
https://doaj.org/article/a64f0305449b4cd8bd310ba984abd2e4
Akademický článek
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Autor:
Duncan Armstrong, David Brott, Lewis B. Kinter, Johannes Harleman, Håkan H. A. S. Andersson, Lorna Ewart, Jane Stewart, Greg Christoph
Publikováno v:
Toxicology Reports, Vol 1, Iss C, Pp 1202-1212 (2014)
Background Ticagrelor is an orally available, direct acting and reversible P2Y 12 receptor antagonist approved for treatment of acute coronary syndrome. The objectives of these studies were to (1) evaluate the Ticagrelor 2-year rat carcinogenicity bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::782ef1db606ddeed7cb148cdf5f3457a
https://doi.org/10.1016/j.toxrep.2014.11.010
https://doi.org/10.1016/j.toxrep.2014.11.010
Publikováno v:
Inhalation Toxicology. 15:781-798
Groups of adult male rats (10/group) were used to assess whether subchronic inhalation exposure to 0, 1000, 2000, or 4000 ppm of acetone vapor altered schedule-controlled operant performance. Rats were exposed to acetone vapor for 6 h/day, 5 days/wk,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66b1acfdaf47442f6cc5cfbb43c58903
https://doi.org/10.1080/08958370390217846
https://doi.org/10.1080/08958370390217846
Publikováno v:
Journal of Experimental Psychology: Animal Behavior Processes. 3:105-118
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b828646ade393603cc3a8de446283f1
https://doi.org/10.1037/0097-7403.3.2.105
https://doi.org/10.1037/0097-7403.3.2.105
Autor:
Markus Artelsmair, Richard J. Lewis, Patty Davis, Chapdelaine Marc, Chungang Gu, Mark A. Smith, Maria Sunzel, Bruce Dembofsky, Charles S. Elmore, James E. Hall, Greg Christoph
Publikováno v:
Drug Metabolism and Disposition
AZD7325 [4-amino-8-(2-fluoro-6-methoxyphenyl)-N-propylcinnoline-3-carboxamide] is a selective GABAAα2,3receptor modulator intended for the treatment of anxiety disorders through oral administration. An interesting metabolic cyclization and aromatiza
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e30f5a378c5f7768551672d226e04567