Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Greg C. Bristow"'
Autor:
Rebecca L. Openshaw, David M. Thomson, Greg C. Bristow, Emma J. Mitchell, Judith A. Pratt, Brian J. Morris, Neil Dawson
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)
Abstract Autism spectrum disorders are more common in males, and have a substantial genetic component. Chromosomal 16p11.2 deletions in particular carry strong genetic risk for autism, yet their neurobiological impact is poorly characterised, particu
Externí odkaz:
https://doaj.org/article/a9c33b7142af4f94937b2541091f6e9d
Autor:
Adam Jameson, Beth Fylan, Greg C. Bristow, Gurdeep S. Sagoo, Caroline Dalton, Alastair Cardno, Jaspreet Sohal, Samantha L. McLean
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
In psychiatry, the selection of antipsychotics and antidepressants is generally led by a trial-and-error approach. The prescribing of these medications is complicated by sub-optimal efficacy and high rates of adverse drug reactions (ADRs). These both
Externí odkaz:
https://doaj.org/article/0b71a8354b7b4fa8901fd09fc9ba8e8c
Autor:
Greg C. Bristow, David M. Thomson, Rebecca L. Openshaw, Emma J. Mitchell, Judith A. Pratt, Neil Dawson, Brian J. Morris
Publikováno v:
Cell Reports, Vol 31, Iss 3, Pp - (2020)
Summary: Chromosome 16p11.2 duplications dramatically increase risk for schizophrenia, but the mechanisms remain largely unknown. Here, we show that mice with an equivalent genetic mutation (16p11.2 duplication mice) exhibit impaired hippocampal-orbi
Externí odkaz:
https://doaj.org/article/7728d8dbc8bd473aafcc7b7820bf4f24
Autor:
Adam Jameson, Muhammad Faisal, Beth Fylan, Greg C. Bristow, Gurdeep S. Sagoo, Caroline Dalton, Alastair Cardno, Jaspreet Sohal, Samantha L. McLean
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a61a7dfef6950bcd0d58896aaed98458
https://doi.org/10.2139/ssrn.4429212
https://doi.org/10.2139/ssrn.4429212
Publikováno v:
Journal of affective disorders. 295
Background Accumulating evidence indicates that reduced activity within the monoamine systems contributes to the pathophysiology of major depressive disorder (MDD) and suicide. In this study, we have tested the hypothesis that monoaminergic gene tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::619ce28bf458508585f406ddea03905a
https://pubmed.ncbi.nlm.nih.gov/34706435
https://pubmed.ncbi.nlm.nih.gov/34706435
Autor:
Shivali Kohli, Mohammad Alsaad, Isra Alsaady, Jonathan M. Wastling, M. S. Vijayabaskar, Matthew B. Reeves, Glenn A. McConkey, Ellen Tedford, Greg C. Bristow, Steven J. Clapcote, Matthew J Murray
The parasitic protozoan Toxoplasma gondii becomes encysted in brain and muscle tissue during chronic infection, a stage that was previously thought to be dormant but has been found to be active and associated with physiological effects in the host. D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a71930a981a54d30041d7458d095e08b
https://doi.org/10.1101/345900
https://doi.org/10.1101/345900
Autor:
Greg C. Bristow, Monsheel S. Sodhi
Publikováno v:
Biological Psychiatry. 85:S193-S194
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d119a25936e73c1bb19faa27ee23a16b
https://doi.org/10.1016/j.biopsych.2019.03.490
https://doi.org/10.1016/j.biopsych.2019.03.490
Autor:
P.W.J. Burnet, Beata R. Godlewska, Paul Harrison, Sharon L. Eastwood, M A Walker, Greg C. Bristow, Pilleriin Sikka
D-amino acid oxidase (DAO, DAAO) metabolises the NMDA receptor (NMDAR) modulator D-serine.1 Enhanced DAO activity is thus a potential cause of reduced D-serine and thence impaired NMDAR functioning in schizophrenia,2 and an explanation for the geneti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b59d7579c43278cc04418ac18b4897a3
https://ora.ox.ac.uk/objects/uuid:802751c9-0e9c-490e-9867-35b552431fe2
https://ora.ox.ac.uk/objects/uuid:802751c9-0e9c-490e-9867-35b552431fe2
Autor:
M A Walker, Yoshi Sei, Li Chen, Sharon L. Eastwood, Tracy A. Lane, Joel E. Kleinman, Thomas M. Hyde, Greg C. Bristow, Paul Harrison
Publikováno v:
Brain Research. 1301:197-206
Single nucleotide polymorphisms (SNPs) within the gene encoding the serine/threonine kinase KIS (Kinase Interacting with Stathmin, also known as UHMK1) have recently been associated with schizophrenia. As none of the disease associated SNPs are codin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0537cc7d94f8e5d115f4887c75d87890
https://doi.org/10.1016/j.brainres.2009.08.090
https://doi.org/10.1016/j.brainres.2009.08.090
Publikováno v:
Biological Psychiatry. 81:S3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97b03a8d91dae42552de60cad9882106
https://doi.org/10.1016/j.biopsych.2017.02.017
https://doi.org/10.1016/j.biopsych.2017.02.017