Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Greg B G Moorhead"'
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0132863 (2015)
Mg+2/Mn+2-dependent type 2C protein phosphatases (PP2Cs) are ubiquitous in eukaryotes, mediating diverse cellular signaling processes through metal ion catalyzed dephosphorylation of target proteins. We have identified a distinct PP2C sequence class
Externí odkaz:
https://doaj.org/article/ae3f086ac00f4d6eaaf04463a78eef6c
Autor:
Veerle De Wever, David C Lloyd, Isha Nasa, Mhairi Nimick, Laura Trinkle-Mulcahy, Robert Gourlay, Nick Morrice, Greg B G Moorhead
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39510 (2012)
Metazoan mitosis requires remodelling of sub-cellular structures to ensure proper division of cellular and genetic material. Faults often lead to genomic instability, cell cycle arrests and disease onset. These key structural changes are under tight
Externí odkaz:
https://doaj.org/article/b674daa69e1f4f0c8d8b023cea388afa
Publikováno v:
Protein Kinases and Stress Signaling in Plants
Autor:
Tony Ferrar, Delphine Chamousset, Veerle De Wever, Mhairi Nimick, Jens Andersen, Laura Trinkle-Mulcahy, Greg B. G. Moorhead
Publikováno v:
Biology Open, Vol 1, Iss 2, Pp 128-139 (2012)
Summary The promiscuous activity of protein phosphatase one (PP1) is controlled in the cell by associated proteins termed regulatory or targeting subunits. Using biochemical and proteomic approaches we demonstrate that the autosomal recessive nonsynd
Externí odkaz:
https://doaj.org/article/238a250b0f1a4e108c0dd18b2d2c5dc1
Autor:
Greg B. G. Moorhead, Scott A. Gerber, Brooke L. Brauer, Sierra Mitchell, Arminja N. Kettenbach, Kwame Wiredu
Publikováno v:
Nat Protoc
Phosphoprotein phosphatases (PPPs) execute >90% of serine/threonine dephosphorylation in cells and tissues. While the role of PPPs in cell biology and diseases such as cancer, cardiac hypertrophy and Alzheimer’s disease is well established, the mol
Autor:
Ryan Toth, Anne-Marie Labandera, Greg B. G. Moorhead, R. Glen Uhrig, Jayde J. Johnson, Chris White-Gloria
Publikováno v:
Protein Phosphatases and Stress Management in Plants ISBN: 9783030487324
The plant Shewanella-like PPP protein phosphatases, SLP1 and SLP2, are localized to the chloroplast and mitochondria, respectively. Originally uncovered through bioinformatics, these enzymes have been proven to be bona fide protein serine/threonine p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a94fca75da79579d09cb44af9b5dfc35
https://doi.org/10.1007/978-3-030-48733-1_1
https://doi.org/10.1007/978-3-030-48733-1_1
Autor:
Greg B. G. Moorhead, Ryan Toth
Publikováno v:
Encyclopedia of Molecular Pharmacology ISBN: 9783030215736
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e6de08eca73656d2170a84c2917f12e
https://doi.org/10.1007/978-3-030-21573-6_205-1
https://doi.org/10.1007/978-3-030-21573-6_205-1
Autor:
Kyung S. Lee, Isha Nasa, Pauline Douglas, Greg B. G. Moorhead, Susan P. Lees-Miller, Laura Trinkle-Mulcahy, Sibapriya Chaudhuri
Publikováno v:
Biochem Biophys Res Commun
Centrosomal protein of 192 kDa (CEP192) is a scaffolding protein that recruits the mitotic protein kinases Aurora A and PLK1 to the centrosome. Here we demonstrate that CEP192 also recruits the type one protein phosphatase (PP1) via a highly conserve
Autor:
Lay-Yin Tang, Greg B. G. Moorhead, Anne-Claude Gingras, Nicholas A Sieben, Edward C. Yeung, Marilyn Goudreault, Marcus A. Samuel, Glen Uhrig, Anne-Marie Labandera
Publikováno v:
Plant Physiology. 173:956-969
Reversible protein phosphorylation catalyzed by protein kinases and phosphatases represents the most prolific and well-characterized posttranslational modification known. Here, we demonstrate that Arabidopsis (Arabidopsis thaliana) Shewanella-like pr