Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Greg, Finak"'
Autor:
Allan C. deCamp, Martin M. Corcoran, William J. Fulp, Jordan R. Willis, Christopher A. Cottrell, Daniel L. V. Bader, Oleksandr Kalyuzhniy, David J. Leggat, Kristen W. Cohen, Ollivier Hyrien, Sergey Menis, Greg Finak, Lamar Ballweber-Fleming, Abhinaya Srikanth, Jason R. Plyler, Farhad Rahaman, Angela Lombardo, Vincent Philiponis, Rachael E. Whaley, Aaron Seese, Joshua Brand, Alexis M. Ruppel, Wesley Hoyland, Celia R. Mahoney, Alberto Cagigi, Alison Taylor, David M. Brown, David R. Ambrozak, Troy Sincomb, Tina-Marie Mullen, Janine Maenza, Orpheus Kolokythas, Nadia Khati, Jeffrey Bethony, Mario Roederer, David Diemert, Richard A. Koup, Dagna S. Laufer, Juliana M. McElrath, Adrian B. McDermott, Gunilla B. Karlsson Hedestam, William R. Schief
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-13 (2024)
Abstract Vaccine priming immunogens that activate germline precursors for broadly neutralizing antibodies (bnAbs) have promise for development of precision vaccines against major human pathogens. In a clinical trial of the eOD-GT8 60mer germline-targ
Externí odkaz:
https://doaj.org/article/2e580eabca0b4c0f8e97acb243086a89
Autor:
Gemma Moncunill, Jason Carnes, William Chad Young, Lindsay Carpp, Stephen De Rosa, Joseph J Campo, Augusto Nhabomba, Maxmillian Mpina, Chenjerai Jairoce, Greg Finak, Paige Haas, Carl Muriel, Phu Van, Héctor Sanz, Sheetij Dutta, Benjamin Mordmüller, Selidji T Agnandji, Núria Díez-Padrisa, Nana Aba Williams, John J Aponte, Clarissa Valim, Daniel E Neafsey, Claudia Daubenberger, M Juliana McElrath, Carlota Dobaño, Ken Stuart, Raphael Gottardo
Publikováno v:
eLife, Vol 11 (2022)
Background: In a phase 3 trial in African infants and children, the RTS,S/AS01 vaccine (GSK) showed moderate efficacy against clinical malaria. We sought to further understand RTS,S/AS01-induced immune responses associated with vaccine protection. Me
Externí odkaz:
https://doaj.org/article/37c360e9cf6d4232954aa26b5b65805e
Autor:
Srabanti Rakshit, Nitin Hingankar, Shuba Varshini Alampalli, Vasista Adiga, Bharath K. Sundararaj, Pravat Nalini Sahoo, Greg Finak, Anto Jesuraj Uday Kumar J, Chirag Dhar, George D’Souza, Rashmi Govind Virkar, Manisha Ghate, Madhuri R. Thakar, Ramesh S. Paranjape, Stephen C. De Rosa, Tom H.M. Ottenhoff, Annapurna Vyakarnam
Publikováno v:
Cell Reports, Vol 33, Iss 9, Pp 108451- (2020)
Summary: HIV infection predisposes latent tuberculosis-infected (LTBI) subjects to active TB. This study is designed to determine whether HIV infection of LTBI subjects compromises the balanced Mycobacterium tuberculosis (Mtb)-specific T helper 17 (T
Externí odkaz:
https://doaj.org/article/81a63bfce56344609c4df45cb0d72869
Autor:
Kristen W. Cohen, Stephen C. De Rosa, William J. Fulp, Allan C. deCamp, Andrew Fiore-Gartland, Celia R. Mahoney, Sarah Furth, Josh Donahue, Rachael E. Whaley, Lamar Ballweber-Fleming, Aaron Seese, Katharine Schwedhelm, Daniel Geraghty, Greg Finak, Sergey Menis, David J. Leggat, Farhad Rahaman, Angela Lombardo, Bhavesh R. Borate, Vincent Philiponis, Janine Maenza, David Diemert, Orpheus Kolokythas, Nadia Khati, Jeffrey Bethony, Ollivier Hyrien, Dagna S. Laufer, Richard A. Koup, Adrian B. McDermott, William R. Schief, M. Juliana McElrath
Publikováno v:
Science Translational Medicine. 15
The engineered outer domain germline targeting version 8 (eOD-GT8) 60-mer nanoparticle was designed to prime VRC01-class HIV-specific B cells that would need to be matured, through additional heterologous immunizations, into B cells that are able to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0bb3baa4d27b5a5fed41220c33d7d1a5
https://doi.org/10.1126/scitranslmed.adf3309
https://doi.org/10.1126/scitranslmed.adf3309
Autor:
Sara De Biasi, Annalisa Guida, Domenico Lo Tartaro, Martina Fanelli, Roberta Depenni, Massimo Dominici, Greg Finak, Camillo Porta, Annamaria Paolini, Rebecca Borella, Carlo Bertoldi, Andrea Cossarizza, Roberto Sabbatini, Lara Gibellini
Publikováno v:
Cytometry Part A. 101:597-605
Renal-cell carcinoma (RCC) is responsible for the majority of tumors arising from the kidney parenchyma. Although a progressive improvement in median overall survival has been observed after the introduction of anti-PD-1 therapy, many patients do not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73cd4273e4d6708a90c46885b6f364a0
https://doi.org/10.1002/cyto.a.24562
https://doi.org/10.1002/cyto.a.24562
Autor:
Valerie P. O’Brien, Yuqi Kang, Meera K. Shenoy, Greg Finak, William C. Young, Julien Dubrulle, Lisa Koch, Armando E. Rodriguez Martinez, Jazmine A. Snow, Jeffery Williams, Elizabeth Donato, Surinder K. Batra, Cecilia C.S. Yeung, Susan Bullman, Meghan A. Koch, Raphael Gottardo, Nina R. Salama
Mechanisms forHelicobacter pylori(Hp)-driven stomach cancer are not fully understood. In a transgenic mouse model of gastric preneoplasia, concomitantHpinfection and induction of constitutively active KRAS (Hp+KRAS+) alters metaplasia phenotypes and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa1fc21591ef9fdaad8f1713d12a7cd4
https://doi.org/10.1101/2022.12.20.521287
https://doi.org/10.1101/2022.12.20.521287
Autor:
Greg Finak, Bryan Mayer, William Fulp, Paul Obrecht, Alicia Sato, Eva Chung, Drienna Holman, Raphael Gottardo
Publikováno v:
Gates Open Research, Vol 2 (2018)
A central tenet of reproducible research is that scientific results are published along with the underlying data and software code necessary to reproduce and verify the findings. A host of tools and software have been released that facilitate such wo
Externí odkaz:
https://doaj.org/article/c1f9e3210fc9463b8d2747811d713cc5
Autor:
Diane L Bolton, Kathleen McGinnis, Greg Finak, Pratip Chattopadhyay, Raphael Gottardo, Mario Roederer
Publikováno v:
PLoS Pathogens, Vol 13, Iss 6, p e1006445 (2017)
CD4 T cells harboring HIV-1/SIV represent a formidable hurdle to eradicating infection, and yet their detailed phenotype remains unknown. Here we integrate two single-cell technologies, flow cytometry and highly multiplexed quantitative RT-PCR, to ch
Externí odkaz:
https://doaj.org/article/acf6097f96dd4b70bffe9ab1f73e2122
Autor:
Danniel Zamora, Hu Xie, Wendy M. Leisenring, Brenda Akoto, Joshua T. Schiffer, Stephen C. De Rosa, Elizabeth R. Duke, Ralf Wagner, Terry Stevens-Ayers, Greg Finak, Bradley C. Edmison, Michael Boeckh, Richard Kiener, Keith R. Jerome, Marco Mielcarek
Publikováno v:
Blood. 138:34-43
Decreased cytomegalovirus (CMV)-specific immunity after hematopoietic cell transplantation (HCT) is associated with late CMV reactivation and increased mortality. Whether letermovir prophylaxis-associated reduction in viral exposure influences CMV-sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aed5cf39c7c48067dc0d89c7d060c257
https://doi.org/10.1182/blood.2020009396
https://doi.org/10.1182/blood.2020009396
Autor:
Andrew Fiore-Gartland, Bryce A Manso, David P Friedrich, Erin E Gabriel, Greg Finak, Zoe Moodie, Tomer Hertz, Stephen C De Rosa, Nicole Frahm, Peter B Gilbert, M Juliana McElrath
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0147812 (2016)
The interferon gamma, enzyme-linked immunospot (IFN-γ ELISpot) assay is widely used to identify viral antigen-specific T cells is frequently employed to quantify T cell responses in HIV vaccine studies. It can be used to define T cell epitope specif
Externí odkaz:
https://doaj.org/article/c93e1e1a3ed04b8c82312b7c24d8e317