Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Grefachew, Workalemahu"'
Autor:
Budd A. Tucker, Ian C. Han, Adam P. DeLuca, Elizabeth L Kennedy, Zuhair K. Ballas, Todd E. Scheetz, Robert F. Mullins, Elaine M. Binkley, Luke A Wiley, Edwin M. Stone, James C. Folk, Grefachew Workalemahu, Meagan A Luse, Nicole Tatro
Publikováno v:
Retin Cases Brief Rep
PURPOSE: 1) To describe a case of autoimmune retinopathy mimicking heritable photoreceptor degeneration in a patient with common variable immune deficiency, and 2) to investigate the humoral and cell-mediated branches of the immune system in this pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5570c585713a7cd31654ad94b758582d
https://europepmc.org/articles/PMC9211761/
https://europepmc.org/articles/PMC9211761/
Autor:
Young H. Kwon, S. Scott Whitmore, Edwin M. Stone, Grefachew Workalemahu, Michael D. Abràmoff, Miles J. Flamme-Wiese, Robert F. Mullins, Alexander G. Marneros, Kai Wang, Erin A. Boese, Budd A. Tucker, Elliott H. Sohn
Publikováno v:
Am J Pathol
Early age-related macular degeneration (AMD) is characterized by degeneration of the choriocapillaris, the vascular supply of retinal photoreceptor cells. We assessed vascular loss during disease progression in the choriocapillaris and larger vessels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25bc5d9f7421891067fe52f326482478
https://doi.org/10.1016/j.ajpath.2019.04.005
https://doi.org/10.1016/j.ajpath.2019.04.005
Autor:
Robert F. Mullins, Austin J Reutzel, Matthew J. Miller, Joseph C. Giacalone, S. Scott Whitmore, Budd A. Tucker, Edwin M. Stone, Dalyz Ochoa, Grefachew Workalemahu
Publikováno v:
Microvasc Res
Age-related macular degeneration (AMD) is a common cause of blindness worldwide. While recent studies have revealed that the loss of choroidal endothelial cells (ChECs) is critical to the disease pathogenesis of dry AMD, in vitro studies are needed t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a89f929ece0681d436c1c766508e7493
https://doi.org/10.1016/j.mvr.2018.12.002
https://doi.org/10.1016/j.mvr.2018.12.002
Autor:
Xiuying Liu, Meng Wu, Robert F. Mullins, Elliott H. Sohn, Shemin Zeng, Edwin M. Stone, Grefachew Workalemahu, Kathleen R. Chirco, Miles J. Flamme-Wiese, Budd A. Tucker, Kuo-Kuang Wen
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-8 (2018)
Scientific Reports
Scientific Reports
Age-related macular degeneration (AMD) is a common, blinding disease associated with increased complement system activity. Eyes with AMD show elevated accumulation of the membrane attack complex (MAC) in the choriocapillaris and degeneration of macul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a65bec894f2dbc69e36d07667945493c
http://link.springer.com/article/10.1038/s41598-018-31846-z
http://link.springer.com/article/10.1038/s41598-018-31846-z
Publikováno v:
Journal for Immunotherapy of Cancer
Background Human γδ T cells expressing Vγ2Vδ2 T cell receptors monitor foreign- and self-prenyl pyrophosphate metabolites in isoprenoid biosynthesis to mediate immunity to microbes and tumors. Adoptive immunotherapy with Vγ2Vδ2 T cells has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a576ade743663c0beb08dddf1d2349f
http://europepmc.org/articles/PMC5319075
http://europepmc.org/articles/PMC5319075
Publikováno v:
The Journal of Immunology. 202:138.16-138.16
Human γδ T cells expressing Vγ2Vδ2 TCRs monitor foreign- and self-isoprenoid metabolites to mediate immunity to microbes and tumors. Bisphosphonate treatment of tumors increases isopentenyl pyrophosphate that is sensed by butyrophilin 3A1, allowi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b990ce0c051ef0cd4386c6428d41728c
https://doi.org/10.4049/jimmunol.202.supp.138.16
https://doi.org/10.4049/jimmunol.202.supp.138.16
Autor:
Kathleen R, Chirco, Ralph J, Hazlewood, Kathy, Miller, Grefachew, Workalemahu, Lee M, Jampol, G Robert, Lesser, Robert F, Mullins, Markus H, Kuehn, John H, Fingert
Publikováno v:
Molecular Vision
Purpose The defining feature of glaucoma is excavation of the optic nerve head; however, the mechanism of this loss of tissue is not well understood. We recently discovered a copy number variation upstream of matrix metalloproteinase 19 (MMP19) in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::891b18ec458d2dc2a31227663ae782ce
https://pubmed.ncbi.nlm.nih.gov/28003733
https://pubmed.ncbi.nlm.nih.gov/28003733
Autor:
Angelika Reissig, Claus Kroegel, Andreas Machnik, Bettina Mock, Nicole Bergmann, Grefachew Workalemahu, Martin Foerster
Publikováno v:
Respiration. 73:566-570
We report herein the therapeutic effect of interferon (IFN)-αcon in three patients with severe persistent asthma and long-term oral glucocorticoid treatment. IFN-αcon (9 µg) administered subcutaneously thrice a week over a period of more than 24 m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f695cc5813c15041f399c2bff4661e76
https://doi.org/10.1159/000088660
https://doi.org/10.1159/000088660
Publikováno v:
Journal of Cellular Physiology. 207:67-74
Human gammadelta T-lymphocytes are believed to regulate local immune defense and enhance resistance against invading microbes, although their precise function remains unknown. Herein, we addressed the question whether gammadelta T-lymphocytes mediate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56befd7f6525095ca215453b49f62f4f
https://doi.org/10.1002/jcp.20541
https://doi.org/10.1002/jcp.20541
Autor:
Tomohisa Kuzuyama, Kia-Joo Puan, Craig T. Morita, Bradley D. Jones, Mohanad H. Nada, Grefachew Workalemahu, Hong Wang, Chenggang Jin
Human Vγ2Vδ2 T cells monitor isoprenoid metabolism by recognizing foreign (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate (HMBPP), a metabolite in the 2-C-methyl-d-erythritol-4-phosphate pathway used by most eubacteria and apicomplexan parasites, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b0d3a0e226e45f356f81f0fc910d507
https://europepmc.org/articles/PMC4241231/
https://europepmc.org/articles/PMC4241231/