Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Greet Thijs"'
Autor:
Magali de Bruyn, Christine Breynaert, Ingrid Arijs, Gert De Hertogh, Karel Geboes, Greet Thijs, Gianluca Matteoli, Jialiang Hu, Jo Van Damme, Bernd Arnold, Marc Ferrante, Séverine Vermeire, Gert Van Assche, Ghislain Opdenakker
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Metalloproteinase-9 has been suggested as therapeutic target to treat inflammatory bowel disease. Here de Bruynet al. show that genetic and pharmacological inhibition of metalloproteinase-9 does not ameliorate inflammation and fibrosis in mice challe
Externí odkaz:
https://doaj.org/article/cf83337903164ea1a97bfb338b28091a
Autor:
Estefania Ugarte-Berzal, Nele Berghmans, Lise Boon, Erik Martens, Jennifer Vandooren, Bénédicte Cauwe, Greet Thijs, Paul Proost, Jo Van Damme, Ghislain Opdenakker
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0197944 (2018)
Gelatinase B/matrix metalloproteinase-9 (MMP-9) triggers multiple sclerosis (MS) and the animal model of experimental autoimmune encephalomyelitis (EAE) by the breakdown of the blood-brain barrier. Interestingly, MMP-9 is beneficial in systemic autoi
Externí odkaz:
https://doaj.org/article/d0933f0f7fe743618d1d0832dff91c1f
Autor:
Nathalie Geurts, Erik Martens, Sebastien Verhenne, Natacha Lays, Greet Thijs, Stefan Magez, Bénédicte Cauwe, Sandra Li, Hubertine Heremans, Ghislain Opdenakker, Philippe E Van den Steen
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27131 (2011)
The use of genetically modified mice, i.e. transgenic as well as gene knockout (KO) and knock-in mice, has become an established tool to study gene function in many animal models for human diseases. However, a gene functions in a particular genomic c
Externí odkaz:
https://doaj.org/article/17c23f85bcdb468db28ebdc787e462a0
Autor:
Greet Thijs, Gert De Hertogh, Jo Van Damme, Gert Van Assche, Jialiang Hu, Ghislain Opdenakker, Severine Vermeire, Ingrid Arijs, Bernd Arnold, Marc Ferrante, Magali de Bruyn, Gianluca Matteoli, Karel Geboes, Christine Breynaert
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Nature Communications
Nature Communications
One third of patients with inflammatory bowel disease (IBD) inadequately respond to anti-TNF treatment and preclinical data suggest that matrix metalloproteinase-9 (MMP-9) is a novel therapeutic target. Here we show that IBD clinical and histopatholo
Autor:
Jennifer Vandooren, Paul Proost, Greet Thijs, Jo Van Damme, Erik Martens, Estefania Ugarte Berzal, Nele Berghmans, Ghislain Opdenakker, Bénédicte Cauwe, Lise Boon
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0197944 (2018)
PLoS ONE
PLoS ONE
Gelatinase B/matrix metalloproteinase-9 (MMP-9) triggers multiple sclerosis (MS) and the animal model of experimental autoimmune encephalomyelitis (EAE) by the breakdown of the blood-brain barrier. Interestingly, MMP-9 is beneficial in systemic autoi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff3b002aee7be745f7a847b704aa5288
Autor:
Sofie Knoops, K. De Bosscher, Leen Vandermosten, Ghislain Opdenakker, Greet Thijs, Karen E. Chapman, C. De Geest, P. E. Van den Steen
Publikováno v:
Vandermosten, L, De Geest, C, Knoops, S, Thijs, G, Chapman, K, De Bosscher, K, Opdenakker, G & Van den Steen, P E 2017, ' 11β-hydroxysteroid dehydrogenase type 1 has no effect on survival during experimental malaria but affects parasitemia in a parasite strain-specific manner ', Scientific Reports . https://doi.org/10.1038/s41598-017-14288-x
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports
SCIENTIFIC REPORTS
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports
SCIENTIFIC REPORTS
Malaria is a global disease associated with considerable mortality and morbidity. An appropriately balanced immune response is crucial in determining the outcome of malarial infection. The glucocorticoid (GC) metabolising enzyme, 11β-hydroxysteroid
Autor:
Bénédicte Cauwe, Ghislain Opdenakker, Sandra Li, Jan Mertens, Erik Martens, Hubertine Heremans, Nathalie Geurts, Daniel Engelbert Blockmans, Bernd Arnold, Chris Dillen, Rita Vos, Philippe E. Van den Steen, Xavier Sagaert, Greet Thijs
Publikováno v:
Journal of Autoimmunity. 36:239-252
Gelatinase B/matrix metalloproteinase-9 (MMP-9) is a key enzyme involved in inflammatory, hematological, vascular and neoplastic diseases. In previous studies, we explored the intracellular substrate set or ‘degradome’ of MMP-9 and found many sys
Autor:
Magali de Bruyn, Greet Thijs, Gert De Hertogh, Marc Ferrante, Ingrid Arijs, Gert Van Assche, Jialiang Hu, Karel Geboes, Severine Vermeire, Christine Breynaert, Jo Van Damme, Ghislain Opdenakker, Jan Ceuppens, Bernd Arnold
Publikováno v:
Gastroenterology. 150:S968
Autor:
Natacha Lays, Hubertine Heremans, Ghislain Opdenakker, Greet Thijs, Bénédicte Cauwe, Sandra Li, Stefan Magez, Erik Martens, Philippe E. Van den Steen, Sebastien Verhenne, Nathalie Geurts
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 11, p e27131 (2011)
Vrije Universiteit Brussel
PLoS ONE, Vol 6, Iss 11, p e27131 (2011)
Vrije Universiteit Brussel
The use of genetically modified mice, i.e. transgenic as well as gene knockout (KO) and knock-in mice, has become an established tool to study gene function in many animal models for human diseases . However, a gene functions in a particular genomic