Design of high specificity binders for peptide-MHC-I complexes.

Autor: Liu B; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA., Greenwood NF; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA., Bonzanini JE; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.; Bioengineering Graduate Program, University of Washington, Seattle, WA 98195, USA., Motmaen A; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.; Bioengineering Graduate Program, University of Washington, Seattle, WA 98195, USA., Sharp J; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA., Wang C; Departments of Molecular and Cellular Physiology and Structural Biology, Stanford University School of Medicine, Stanford, CA 94305, USA., Visani GM; Paul G. Allen School of Computer Science and Engineering, University of Washington, Seattle, USA., Vafeados DK; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA., Roullier N; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA., Nourmohammad A; Paul G. Allen School of Computer Science and Engineering, University of Washington, Seattle, USA.; Department of Physics, University of Washington, Seattle, WA 98195, USA.; Department of Applied Mathematics, University of Washington, Seattle, WA 98195, USA.; Fred Hutchinson Cancer Center, Seattle, WA 98109, USA., Garcia KC; Departments of Molecular and Cellular Physiology and Structural Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.; Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA., Baker D; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA.; Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Nov 28. Date of Electronic Publication: 2024 Nov 28.