Výsledky vyhledávání - "Greenstein AE"

Akademický článek

Relacorilant + Nab-Paclitaxel in Patients With Recurrent, Platinum-Resistant Ovarian Cancer: A Three-Arm, Randomized, Controlled, Open-Label Phase II Study.

Autor: Colombo N; Gynecologic Oncology Program, European Institute of Oncology, IRCCS, Milan, Italy.; Department of Medicine and Surgery, University Milan-Bicocca, Milan, Italy., Van Gorp T; Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University Hospital Leuven, Leuven Cancer Institute, Leuven, Belgium., Matulonis UA; Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA., Oaknin A; Gynaecologic Cancer Programme, Vall d'Hebron Institute of Oncology (VHIO), Hospital Universitari Vall d'Hebron, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain., Grisham RN; Memorial Sloan Kettering Cancer Center and Weill Cornell Medical Center, New York, NY., Fleming GF; The University of Chicago, Chicago, IL., Olawaiye AB; Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA., Nguyen DD; Corcept Therapeutics Inc, Menlo Park, CA., Greenstein AE; Corcept Therapeutics Inc, Menlo Park, CA., Custodio JM; Corcept Therapeutics Inc, Menlo Park, CA., Pashova HI; Corcept Therapeutics Inc, Menlo Park, CA., Tudor IC; Corcept Therapeutics Inc, Menlo Park, CA., Lorusso D; Fondazione Policlinico Universitario Gemelli IRCCS, Catholic University of Sacred Heart, Rome, Italy.

Publikováno v: Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2023 Oct 20; Vol. 41 (30), pp. 4779-4789. Date of Electronic Publication: 2023 Jun 26.

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Akademický článek

The glucocorticoid receptor modulator relacorilant reverses the immunosuppressive effects of cortisol.

Autor: Greenstein AE; Corcept Therapeutics, 149 Commonwealth Dr, Menlo Park, CA 94025, USA. Electronic address: agreenstein@corcept.com., Hunt HJ; Corcept Therapeutics, 149 Commonwealth Dr, Menlo Park, CA 94025, USA. Electronic address: hhunt@corcept.com.

Publikováno v: International immunopharmacology [Int Immunopharmacol] 2023 Jul; Vol. 120, pp. 110312. Date of Electronic Publication: 2023 May 23.

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Akademický článek

Genetically engineered human pituitary corticotroph tumor organoids exhibit divergent responses to glucocorticoid receptor modulators.

Autor: Mallick S; Department of Cellular and Molecular Medicine, University of Arizona College of Medicine, Tucson, Arizona., Chakrabarti J; Department of Cellular and Molecular Medicine, University of Arizona College of Medicine, Tucson, Arizona., Eschbacher J; Department of Neuropathology, Barrow Neurological Institute, Phoenix, Arizona., Moraitis AG; Corcept Therapeutics, Inc, Menlo Park, California., Greenstein AE; Corcept Therapeutics, Inc, Menlo Park, California., Churko J; Department of Cellular and Molecular Medicine, University of Arizona College of Medicine, Tucson, Arizona., Pond KW; Department of Cellular and Molecular Medicine, University of Arizona College of Medicine, Tucson, Arizona., Livolsi A; MilliporeSigma - Life Science, Rockville, Maryland., Thorne CA; Department of Cellular and Molecular Medicine, University of Arizona College of Medicine, Tucson, Arizona., Little AS; Department of Neurosurgery, Barrow Neurological Institute, Phoenix, Arizona., Yuen KCJ; Department of Neuroendocrinology, Barrow Neurological Institute, Phoenix, Arizona., Zavros Y; Department of Cellular and Molecular Medicine, University of Arizona College of Medicine, Tucson, Arizona. Electronic address: yzavros@arizona.edu.

Publikováno v: Translational research : the journal of laboratory and clinical medicine [Transl Res] 2023 Jun; Vol. 256, pp. 56-72. Date of Electronic Publication: 2023 Jan 12.

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Akademický článek

Characterization of Active MMP9 in Chronic Inflammatory Diseases Using a Novel Anti-MMP9 Antibody.

Autor: Velasquez M; Gilead Sciences, Inc., Foster City, CA 94404, USA., O'Sullivan C; Gilead Sciences, Inc., Foster City, CA 94404, USA., Brockett R; Gilead Sciences, Inc., Foster City, CA 94404, USA., Mikels-Vigdal A; Gilead Sciences, Inc., Foster City, CA 94404, USA., Mikaelian I; Gilead Sciences, Inc., Foster City, CA 94404, USA., Smith V; Gilead Sciences, Inc., Foster City, CA 94404, USA., Greenstein AE; Gilead Sciences, Inc., Foster City, CA 94404, USA.; Corcept Therapeutics, 149 Commonwealth Dr, Menlo Park, CA 94025, USA.

Publikováno v: Antibodies (Basel, Switzerland) [Antibodies (Basel)] 2023 Jan 18; Vol. 12 (1). Date of Electronic Publication: 2023 Jan 18.

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Akademický článek

Evaluation of the matrix metalloproteinase 9 (MMP9) inhibitor Andecaliximab as an Anti-invasive therapeutic in Head and neck squamous cell carcinoma.

Autor: Allen JL; Program in Cancer Cell Biology, Department of Biochemistry, West Virginia University, Morgantown, WV, 26506, United States., Hames RA; Program in Cancer Cell Biology, Department of Biochemistry, West Virginia University, Morgantown, WV, 26506, United States., Mastroianni NM; Program in Cancer Cell Biology, Department of Biochemistry, West Virginia University, Morgantown, WV, 26506, United States., Greenstein AE; Gilead Sciences, Inc., Foster City, CA 94404, United States., Weed SA; Program in Cancer Cell Biology, Department of Biochemistry, West Virginia University, Morgantown, WV, 26506, United States. Electronic address: scweed@hsc.wvu.edu.

Publikováno v: Oral oncology [Oral Oncol] 2022 Sep; Vol. 132, pp. 106008. Date of Electronic Publication: 2022 Jul 06.

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Akademický článek

Overcoming Taxane Resistance: Preclinical and Phase 1 Studies of Relacorilant, a Selective Glucocorticoid Receptor Modulator, with Nab-Paclitaxel in Solid Tumors.

Autor: Munster PN; Department of Medicine (Hematology/Oncology), University of California San Francisco, San Francisco, California., Greenstein AE; Corcept Therapeutics, Menlo Park, California., Fleming GF; Department of Medicine, the University of Chicago, Chicago, Illinois., Borazanci E; HonorHealth Research Institute, Scottsdale, Arizona., Sharma MR; Department of Medicine, the University of Chicago, Chicago, Illinois., Custodio JM; Corcept Therapeutics, Menlo Park, California., Tudor IC; Corcept Therapeutics, Menlo Park, California., Pashova HI; Corcept Therapeutics, Menlo Park, California., Shepherd SP; Corcept Therapeutics, Menlo Park, California., Grauer A; Corcept Therapeutics, Menlo Park, California., Sachdev JC; HonorHealth Research Institute, Scottsdale, Arizona.

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2022 Aug 02; Vol. 28 (15), pp. 3214-3224.

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Akademický článek

Adrenal tumors provide insight into the role of cortisol in NK cell activity.

Autor: Greenstein AE; Corcept Therapeutics, Menlo Park, California, USA., Habra MA; Department of Endocrine Neoplasia and Hormonal Disorders, MD Anderson Cancer Center, Houston, Texas, USA., Wadekar SA; Corcept Therapeutics, Menlo Park, California, USA., Grauer A; Corcept Therapeutics, Menlo Park, California, USA.

Publikováno v: Endocrine-related cancer [Endocr Relat Cancer] 2021 Jun 29; Vol. 28 (8), pp. 583-592. Date of Electronic Publication: 2021 Jun 29.

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Akademický článek

An integrated framework for quantifying immune-tumour interactions in a 3D co-culture model.

Autor: Al-Hity G; School of Pharmacy and Biomolecular sciences, University of Brighton, Centre for Stress and Age-related Diseases, Moulsecoomb, Brighton, BN2, 4GJ, UK., Yang F; Department of Chemical and Process Engineering, University of Surrey, Surrey, UK., Campillo-Funollet E; Genome Damage and Stability Centre, University of Sussex, Falmer, Brighton, BN1 9QH, UK., Greenstein AE; Corcept Therapeutics, 149 Commonwealth Drive, Menlo Park, California, 94025, United States., Hunt H; Corcept Therapeutics, 149 Commonwealth Drive, Menlo Park, California, 94025, United States., Mampay M; School of Pharmacy and Biomolecular sciences, University of Brighton, Centre for Stress and Age-related Diseases, Moulsecoomb, Brighton, BN2, 4GJ, UK., Intabli H; School of Pharmacy and Biomolecular sciences, University of Brighton, Centre for Stress and Age-related Diseases, Moulsecoomb, Brighton, BN2, 4GJ, UK., Falcinelli M; School of Pharmacy and Biomolecular sciences, University of Brighton, Centre for Stress and Age-related Diseases, Moulsecoomb, Brighton, BN2, 4GJ, UK., Madzvamuse A; School of Mathematical and Physical Sciences, University of Sussex, Department of Mathematics, Falmer, Brighton, BN1 9QH, UK. A.Madzvamuse@sussex.ac.uk., Venkataraman C; School of Mathematical and Physical Sciences, University of Sussex, Department of Mathematics, Falmer, Brighton, BN1 9QH, UK. C.Venkataraman@sussex.ac.uk., Flint MS; School of Pharmacy and Biomolecular sciences, University of Brighton, Centre for Stress and Age-related Diseases, Moulsecoomb, Brighton, BN2, 4GJ, UK. M.Flint@brighton.ac.uk.

Publikováno v: Communications biology [Commun Biol] 2021 Jun 24; Vol. 4 (1), pp. 781. Date of Electronic Publication: 2021 Jun 24.

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