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Insights into the role of JAK2-I724T variant in myeloproliferative neoplasms from a unique cohort of New Zealand patients.

Autor: Puli'uvea C; Department of Molecular Medicine and Pathology, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, Hosted by the University of Auckland, Auckland, New Zealand., Immanuel T; Department of Molecular Medicine and Pathology, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand., Green TN; Department of Molecular Medicine and Pathology, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand., Tsai P; Department of Molecular Medicine and Pathology, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, Hosted by the University of Auckland, Auckland, New Zealand., Shepherd PR; Department of Molecular Medicine and Pathology, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, Hosted by the University of Auckland, Auckland, New Zealand., Kalev-Zylinska ML; Department of Molecular Medicine and Pathology, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand.; Department of Pathology and Laboratory Medicine, Auckland City Hospital, Auckland, New Zealand.

Publikováno v: Hematology (Amsterdam, Netherlands) [Hematology] 2024 Dec; Vol. 29 (1), pp. 2297597. Date of Electronic Publication: 2024 Jan 10.

Deletion of Grin1 in mouse megakaryocytes reveals NMDA receptor role in platelet function and proplatelet formation.

Autor: Hearn JI; Blood and Cancer Biology Laboratory, Department of Molecular Medicine and Pathology, School of Medical Sciences, and., Green TN; Blood and Cancer Biology Laboratory, Department of Molecular Medicine and Pathology, School of Medical Sciences, and., Hisey CL; Hub for Extracellular Vesicle Investigations, School of Medicine, University of Auckland, Auckland, New Zealand., Bender M; Institute of Experimental Biomedicine-Chair I, University Hospital and Rudolf Virchow Center, Würzburg, Germany., Josefsson EC; Department of Medical Biology, University of Melbourne, Melbourne, Australia.; Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia., Knowlton N; Bioinformatics of Disease Research Group, Department of Molecular Medicine and Pathology, School of Medical Sciences.; Maurice Wilkins Centre for Molecular Biodiscovery, School of Biological Sciences., Baumann J; Institute of Experimental Biomedicine-Chair I, University Hospital and Rudolf Virchow Center, Würzburg, Germany., Poulsen RC; Department of Pharmacology and Clinical Pharmacology, School of Medical Sciences.; Department of Medicine, School of Medicine, and., Bohlander SK; Leukaemia and Blood Cancer Research Unit, Department of Molecular Medicine and Pathology, University of Auckland, Auckland, New Zealand; and., Kalev-Zylinska ML; Blood and Cancer Biology Laboratory, Department of Molecular Medicine and Pathology, School of Medical Sciences, and.; Haematology Laboratory, Department of Pathology and Laboratory Medicine, Auckland City Hospital, Auckland, New Zealand.

Publikováno v: Blood [Blood] 2022 Apr 28; Vol. 139 (17), pp. 2673-2690.

Platelet-Reactive Antibodies in Patients after Ischaemic Stroke-An Epiphenomenon or a Natural Protective Mechanism.

Autor: Park YE; Blood and Cancer Biology Laboratory, Department of Molecular Medicine & Pathology, University of Auckland, Auckland 1142, New Zealand., Penumarthy R; Blood and Cancer Biology Laboratory, Department of Molecular Medicine & Pathology, University of Auckland, Auckland 1142, New Zealand., Sun PP; Blood and Cancer Biology Laboratory, Department of Molecular Medicine & Pathology, University of Auckland, Auckland 1142, New Zealand., Kang CY; Blood and Cancer Biology Laboratory, Department of Molecular Medicine & Pathology, University of Auckland, Auckland 1142, New Zealand., Morel-Kopp MC; Department of Haematology and Transfusion Medicine, Royal North Shore Hospital, Sydney 2065, Australia.; Northern Blood Research Centre, Kolling Institute, University of Sydney, Sydney 2065, Australia., Downing J; New Zealand Blood Service Centre, Auckland 1051, New Zealand., Green TN; Blood and Cancer Biology Laboratory, Department of Molecular Medicine & Pathology, University of Auckland, Auckland 1142, New Zealand., Immanuel T; Blood and Cancer Biology Laboratory, Department of Molecular Medicine & Pathology, University of Auckland, Auckland 1142, New Zealand., Ward CM; Department of Haematology and Transfusion Medicine, Royal North Shore Hospital, Sydney 2065, Australia.; Northern Blood Research Centre, Kolling Institute, University of Sydney, Sydney 2065, Australia., Young D; Department of Pharmacology and Clinical Pharmacology, University of Auckland, Auckland 1142, New Zealand.; Centre for Brain Research, University of Auckland, Auckland 1142, New Zealand., During MJ; Centre for Brain Research, University of Auckland, Auckland 1142, New Zealand.; Departments of Molecular Virology, Immunology and Medical Genetics, Neuroscience and Neurological Surgery, Ohio State University, Columbus, OH 43210, USA., Barber PA; Centre for Brain Research, University of Auckland, Auckland 1142, New Zealand.; Department of Neurology, Auckland City Hospital, Auckland 1148, New Zealand., Kalev-Zylinska ML; Blood and Cancer Biology Laboratory, Department of Molecular Medicine & Pathology, University of Auckland, Auckland 1142, New Zealand.; Department of Pathology and Laboratory Medicine, LabPlus Haematology, Auckland City Hospital, Auckland 1148, New Zealand.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2020 Nov 09; Vol. 21 (21). Date of Electronic Publication: 2020 Nov 09.

N-Methyl-D-Aspartate Receptor Hypofunction in Meg-01 Cells Reveals a Role for Intracellular Calcium Homeostasis in Balancing Megakaryocytic-Erythroid Differentiation.

Autor: Hearn JI; Department of Molecular Medicine and Pathology, School of Medical Sciences, University of Auckland, Auckland, New Zealand., Green TN; Department of Molecular Medicine and Pathology, School of Medical Sciences, University of Auckland, Auckland, New Zealand., Chopra M; Department of Molecular Medicine and Pathology, School of Medical Sciences, University of Auckland, Auckland, New Zealand., Nursalim YNS; Department of Molecular Medicine and Pathology, School of Medical Sciences, University of Auckland, Auckland, New Zealand., Ladvanszky L; Department of Molecular Medicine and Pathology, School of Medical Sciences, University of Auckland, Auckland, New Zealand., Knowlton N; Department of Molecular Medicine and Pathology, School of Medical Sciences, University of Auckland, Auckland, New Zealand., Blenkiron C; Department of Molecular Medicine and Pathology, School of Medical Sciences, University of Auckland, Auckland, New Zealand., Poulsen RC; Department of Medicine, School of Medicine, University of Auckland, Auckland, New Zealand.; Department of Pharmacology and Clinical Pharmacology, School of Medical Sciences, University of Auckland, Auckland, New Zealand., Singleton DC; Auckland Cancer Society Research Centre, University of Auckland, Auckland, New Zealand., Bohlander SK; Department of Molecular Medicine and Pathology, School of Medical Sciences, University of Auckland, Auckland, New Zealand., Kalev-Zylinska ML; Department of Molecular Medicine and Pathology, School of Medical Sciences, University of Auckland, Auckland, New Zealand.; LabPlus Haematology, Auckland City Hospital, Auckland, New Zealand.

Publikováno v: Thrombosis and haemostasis [Thromb Haemost] 2020 Apr; Vol. 120 (4), pp. 671-686. Date of Electronic Publication: 2020 Apr 14.