Uptake, efficacy, and systemic distribution of naked, inhaled short interfering RNA (siRNA) and locked nucleic acid (LNA) antisense.

Autor: Moschos SA; Biotherapeutics, Pfizer Global Research and Development, Sandwich, UK. s.moschos@wmin.ac.uk, Frick M, Taylor B, Turnpenny P, Graves H, Spink KG, Brady K, Lamb D, Collins D, Rockel TD, Weber M, Lazari O, Perez-Tosar L, Fancy SA, Lapthorn C, Green MX, Evans S, Selby M, Jones G, Jones L, Kearney S, Mechiche H, Gikunju D, Subramanian R, Uhlmann E, Jurk M, Vollmer J, Ciaramella G, Yeadon M

Publikováno v: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2011 Dec; Vol. 19 (12), pp. 2163-8. Date of Electronic Publication: 2011 Oct 04.