Zobrazeno 1 - 10
of 261
pro vyhledávání: '"Greaves, DR"'
Autor:
Purvis, GSD, Collino, M, Aranda-Tavio, H, Chiazza, F, O'Riordan, CE, Zeboudj, L, Mohammad, S, Collotta, D, Verta, R, Guisot, NES, Bunyard, P, Yaqoob, MM, Greaves, DR, Thiemermann, C
Background and Purpose Currently there are limited medicines available for the treatment of metabolic inflammation in diseases such as obesity and type 2 diabetes (T2D). Although initially associated with B‐ells, Bruton's tyrosine kinase (BTK) is p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1064::f423aaf8138a1c3306e37097c01d9273
https://ora.ox.ac.uk/objects/uuid:f11d90b0-752c-4153-82e3-3c99e505acff
https://ora.ox.ac.uk/objects/uuid:f11d90b0-752c-4153-82e3-3c99e505acff
Autor:
Kapellos, TS, Taylor, L, Feuerborn, A, Valaris, S, Hussain, MT, Rainger, GE, Greaves, DR, Iqbal, AJ, Needham, G
Publikováno v:
FASEB Journal. 33(5)
Cannabinoid receptor (CB)2 is an immune cell-localized GPCR that has been hypothesized to regulate the magnitude of inflammatory responses. However, there is currently no consensus as to the mechanism by which CB2 mediates its anti-inflammatory effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1064::226f7ba0d8e60ba9204e04076fb352fc
http://ora.ox.ac.uk/objects/uuid:
http://ora.ox.ac.uk/objects/uuid:
Autor:
Recio, CP, Lucy, D, Purvis, GSD, Iveson, P, Zeboudj, L, Iqbal, AJ, Lin, D, O’Callaghan, C, Davison, L, Griesbach, E, Russell, AJ, Wynne, GM, Dib, L, Monaco, C, Greaves, DR
Publikováno v:
Frontiers in Immunology. 9
GPR84 is a member of the metabolic G protein-coupled receptor family, and its expression has been described predominantly in immune cells. GPR84 activation is involved in the inflammatory response, but the mechanisms by which it modulates inflammatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0da07d54c8858bd2128b9c43b2b01538
Matrix metalloproteinase-2 (MMP-2) is an enzyme with proteolytic activity against matrix and nonmatrix proteins, particularly basement membrane constituents. Thus, any naturally occurring genetic variants that directly affect gene expression and/or p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::8d687d2405769f5495e9c9ddf96ad050
https://doi.org/10.1074/jbc.m010242200
https://doi.org/10.1074/jbc.m010242200
Mϕs promote tissue injury or repair depending on their activation status and the local cytokine milieu. It remains unclear whether the immunosuppressive effects of transforming growth factor β (TGF-β) serve a nonredundant role in Mϕ function in v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::24e34f6f5fde1965a22008271e0d30e6
https://ora.ox.ac.uk/objects/uuid:f411d589-6c73-411f-9558-8a28614cb81c
https://ora.ox.ac.uk/objects/uuid:f411d589-6c73-411f-9558-8a28614cb81c