Multiparametric analysis of anti-proliferative and apoptotic effects of gold nanoprisms on mouse and human primary and transformed cells, biodistribution and toxicity in vivo

Autor: Marta Pérez-Hernández, María Moros, Grazyna Stepien, Pablo del Pino, Sebastián Menao, Marcelo de las Heras, Maykel Arias, Scott G. Mitchell, Beatriz Pelaz, Eva M. Gálvez, Jesús M. de la Fuente, Julián Pardo

Publikováno v: Particle and Fibre Toxicology, Vol 14, Iss 1, Pp 1-20 (2017)

Abstract Background The special physicochemical properties of gold nanoprisms make them very useful for biomedical applications including biosensing and cancer therapy. However, it is not clear how gold nanoprisms may affect cellular physiology inclu

Externí odkaz: https://doaj.org/article/21a9fc49f2dc42339a6c41f094e8adbc

Effect of Surface Chemistry and Associated Protein Corona on the Long-Term Biodegradation of Iron Oxide Nanoparticles In Vivo

Autor: Julián Pardo, María Moros, Raluca M. Fratila, Grazyna Stepien, Marta Monge, Lucía Gutiérrez, Marcelo de las Heras, Conxita Solans, Juan José Puente Lanzarote, Marta Pérez-Hernández, Jesús M. de la Fuente, Sebastián Menao Guillén

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname

The protein corona formed on the surface of a nanoparticle in a biological medium determines its behavior in vivo. Herein, iron oxide nanoparticles containing the same core and shell, but bearing two different surface coatings, either glucose or poly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dafc479b83b4820295872769c9bfee5
https://doi.org/10.1021/acsami.7b18648

In vitro cell cytotoxicity profile and morphological response to polyoxometalate-stabilised gold nanoparticles

Autor: María Moros, Isabel Maicas Gabas, Jesús M. de la Fuente, Scott G. Mitchell, Grazyna Stepien

Publikováno v: Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
BASE-Bielefeld Academic Search Engine
Digital.CSIC. Repositorio Institucional del CSIC
New journal of chemistry (1987) 40 (2016): 1039–1047. doi:10.1039/c5nj02775f
info:cnr-pdr/source/autori:Gabas I.M.; Stepien G.; Moros M.; Mitchell S.G.; De La Fuente J.M./titolo:In vitro cell cytotoxicity profile and morphological response to polyoxometalate-stabilised gold nanoparticles/doi:10.1039%2Fc5nj02775f/rivista:New journal of chemistry (1987)/anno:2016/pagina_da:1039/pagina_a:1047/intervallo_pagine:1039–1047/volume:40

The size and redox properties of molecular polyoxometalates (POMs) make them extremely relevant for bioapplications: from disrupting tumour growth and enzyme inhibition, to DNA-intercalating agents and antimicrobial applications. Their unique ability

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7404759bc27ef542f417db95a474767a
https://doi.org/10.1039/c5nj02775f

Multiparametric analysis of anti-proliferative and apoptotic effects of gold nanoprisms on mouse and human primary and transformed cells, biodistribution and toxicity in vivo

Autor: Marcelo de las Heras, Marta Pérez-Hernández, Sebastián Menao, María Moros, Grazyna Stepien, Beatriz Pelaz, Eva M. Galvez, Pablo del Pino, Jesús M. de la Fuente, Scott G. Mitchell, Julián Pardo, Maykel Arias

Publikováno v: Particle and Fibre Toxicology
Particle and fibre toxicology 14 (2017). doi:10.1186/s12989-017-0222-4
info:cnr-pdr/source/autori:Perez-Hernandez M.; Moros M.; Stepien G.; del Pino P.; Menao S.; de las Heras M.; Arias M.; Mitchell S.G.; Pelaz B.; Galvez E.M.; de la Fuente J.M.; Pardo J./titolo:Multiparametric analysis of anti-proliferative and apoptotic effects of gold nanoprisms on mouse and human primary and transformed cells, biodistribution and toxicity in vivo/doi:10.1186%2Fs12989-017-0222-4/rivista:Particle and fibre toxicology/anno:2017/pagina_da:/pagina_a:/intervallo_pagine:/volume:14
Particle and Fibre Toxicology, Vol 14, Iss 1, Pp 1-20 (2017)
Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
Digital.CSIC. Repositorio Institucional del CSIC

[Background]: The special physicochemical properties of gold nanoprisms make them very useful for biomedical applications including biosensing and cancer therapy. However, it is not clear how gold nanoprisms may affect cellular physiology including v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f69b116fcc27bb02703b268274b5e511
http://europepmc.org/articles/PMC5658988

Gold nanoprism-nanorod face off: comparing the heating efficiency, cellular internalization and thermoablation capacity

Autor: Gabriel Alfranca, María Moros, Grazyna Stepien, Scott G. Mitchell, Jesús M. de la Fuente, Álvaro Artiga

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
Nanomedicine
Nanomedicine (Lond., Print) 11 (2016): 2903–2916. doi:10.2217/nnm-2016-0257
info:cnr-pdr/source/autori:Alfranca G.; Artiga A.; Stepien G.; Moros M.; Mitchell S.G.; De La Fuente J.M./titolo:Gold nanoprism-nanorod face off: Comparing the heating efficiency, cellular internalization and thermoablation capacity/doi:10.2217%2Fnnm-2016-0257/rivista:Nanomedicine (Lond., Print)/anno:2016/pagina_da:2903/pagina_a:2916/intervallo_pagine:2903–2916/volume:11

[Aim]: This work compares the synthesis, heating capability, cellular internalization and thermoablation capacity of two different types of anisotropic gold nanoparticles: gold nanorods (NRs) and nanoprisms (NPrs). [Methods]: Both particles possess s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5feec86052604d444a4aa57c4fb54fbf
https://pubmed.ncbi.nlm.nih.gov/27785974