Defining Optimal Triage Strategies for hrHPV Screen–Positive Women—An Evaluation of HPV 16/18 Genotyping, Cytology, and p16/Ki-67 Cytoimmunochemistry

Autor: Grazyna A. Stanczuk, Timothy M. Palmer, Marc Arbyn, William Forson, Lynne Patterson, Janice Black, Gwen Baxter, Lynn Govan, Kate Cuschieri, Heather Currie, A. Wilson, James R. Lawrence

Publikováno v: Stanczuk, G A, Baxter, G J, Currie, H, Forson, W, Lawrence, J R, Cuschieri, K, Wilson, A, Patterson, L, Govan, L, Black, J, Palmer, T & Arbyn, M 2017, ' Defining optimal triage strategies for hrHPV screen positive women-an evaluation of HPV 16/18 genotyping, cytology and p16/Ki-67 cyto-immunochemistry. ', Cancer Epidemiology, Biomarkers and Prevention, pp. cebp.0534.2017 . https://doi.org/10.1158/1055-9965.EPI-17-0534

Background: Several options for the triage of high-risk HPV screen–positive (hrHPV+) women were assessed. Methods: This study incorporated CIN2+ cases and controls, all of whom tested hrHPV+ and whose results of liquid-based cytology (LBC), HPV16/1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b980f8d0e71dc05e1770242a4b88687e
https://doi.org/10.1158/1055-9965.epi-17-0534

Typing of human papillomavirus in Zimbabwean patients with invasive cancer of the uterine cervix

Autor: Patti Kay, S. A. Tswana, Anna-Lise Williamson, Mike Chirara, Staffan Bergström, Grazyna A. Stanczuk, Bruce Allan, Elopy Sibanda

Publikováno v: Acta Obstetricia et Gynecologica Scandinavica. 82:762-766

Background. Cervical cancer affects 1 in 2000 Zimbabwean women. We investigated the type-specific distribution of human papillomavirus (HPV) infection in Zimbabwean women with invasive cervical cancer. Methods. We conducted a descriptive study on 98

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0bd5b72399e6888bc2c0f350608d3de4
https://doi.org/10.1034/j.1600-0412.2003.00245.x

Polymorphism in codons 10 and 25 of the transforming growth factor-beta 1 (TGF-β1) gene in patients with invasive squamous cell carcinoma of the uterine cervix

Autor: S.A. Tswana, S. Bergstrom, E. N. Sibanda, Grazyna A. Stanczuk

Publikováno v: European Journal of Immunogenetics. 29:417-421

Transforming growth factor-beta 1 (TGF-beta1) has a multifactorial role in the development of cervical cancer. It potently inhibits the growth of epithelial cells that harbour oncogenic human papilloma viruses (HPVs). TGF-beta1 also inhibits the expr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f5a262680ddb98f158c0e5b448c79579
https://doi.org/10.1046/j.1365-2370.2002.00347.x

Clinical validation of hrHPV testing on vaginal and urine self-samples in primary cervical screening (cross-sectional results from the Papillomavirus Dumfries and Galloway—PaVDaG study)

Autor: Kate Cuschieri, Gwendoline Baxter, Marc Arbyn, Grazyna A. Stanczuk, James R. Lawrence, Heather Currie, A. Wilson

Publikováno v: BMJ Open

Objectives Papillomavirus Dumfries and Galloway (PaVDaG) assessed the performance of a high-risk human papillomavirus (hrHPV) PCR-based assay to detect high-grade cervical intraepithelial neoplasia (CIN2+) in self-collected vaginal and urine samples.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cae22aa67b0830254ad036e6f4dd6ec
https://doi.org/10.1136/bmjopen-2015-010660

HIV/AIDS in Central Africa: pathogenesis, immunological and medical issues

Autor: Grazyna A. Stanczuk, Elopy Sibanda, Francis Kasolo

Publikováno v: International archives of allergy and immunology. 132(3)

The estimated worldwide prevalence of human immunodeficiency virus (HIV) infections topped 52.5 million in June 2003, a mere 20 years after the aetiological agent was shown to be a sexually transmissible virus with a predilection for CD4+ T lymphocyt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::190f74f6bcc66c403228d0fea3666b12
https://pubmed.ncbi.nlm.nih.gov/14646379