Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Grazyna, Kurylko"'
Autor:
Tina Molinaro, Robert Alan Goodnow, Louis M. Renzetti, Alexandra Hicks, Satish Choudhry, Xin Wei, Gesine J. Hermann, Qi Qiao, Anjula Pamidimukkala, A. Robert Catala, Maureen Hargaden, Jian Ping Lou, Nadine Tare, John O’Neil, Ueli Gubler, Karen Pozzani, David J Moore, Jennifer Santiago, Ruben Marcano, Paul Gillespie, Rachid Hamid, Noal Cohen, Hyesun Oh, Lisa C. F. Chao, Laura Singer, Jefferson Wright Tilley, Romyr Dominique, Grazyna Kurylko, Ying L. Li, Radhika Venkat, Achyutharao Sidduri, Matthew Blake Wright, Ann F. Hoffman, Shahid Tannu, Gary Cavallo, Nader Fotouhi, Thomas Egan, Martin Lamb, Jessica D. Ventre, Agnieszka Kowalczyk, D Lavelle, Helena Mancebo
Publikováno v:
Journal of Medicinal Chemistry. 53:3502-3516
The inhibition of LTB(4) binding to and activation of G-protein-coupled receptors BLT1 and BLT2 is the premise of a treatment for several inflammatory diseases. In a lead optimization effort starting with the leukotriene B(4) (LTB(4)) receptor antago
Autor:
Keith A. Yagaloff, Xin-Jie Chu, Lucia Franco, Mitch Yeon, Grazyna Kurylko, Lida Qi, Li Chen, Adrian Wai-Hing Cheung, Karen Rowan, Joseph Swistok, Waleed Danho
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 13:1307-1311
A series of MT-II related cyclic peptides, based on potent but non-selective hMC4R agonist (Penta-c[Asp-His(6)-DPhe(7)-Arg(8)-Trp(9)-Lys]-NH(2)) was prepared in which His(6) residue was systematically substituted. Two of the most interesting peptides
Autor:
Adrian Wai-Hing, Cheung, Waleed, Danho, Joseph, Swistok, Lida, Qi, Grazyna, Kurylko, Lucia, Franco, Keith, Yagaloff, Li, Chen
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 12:2407-2410
A series of pentapeptides, based on Bu-His(6)-DPhe(7)-Arg(8)-Trp(9)-Gly(10)-NH(2) and modified at the Arg(8) position, was prepared and pharmacologically characterized. Peptides containing either cyanoguanidine or acylguanidine, two substantially les
Autor:
Anjula Pamidimukkala, Jian Ping Lou, Paul Gillespie, Rachid Hamid, Hyesun Oh, Thomas H. March, D Lavelle, Lisa C. F. Chao, Tina Molinaro, Matthew Blake Wright, Martin Brovarney, A. Robert Catala, John O’Neil, Agnieszka Kowalczyk, Louis M. Renzetti, Nader Fotouhi, Maureen Hargaden, John Satjawatcharaphong, Karen Pozzani, Xin Wei, Thomas Egan, Radhika Venkat, Ruben Marcano, Shahid Tannu, Karim Dabbagh, Helena Mancebo, Laura Singer, Martin Lamb, David J Moore, Jessica D. Ventre, Janet M. Benson, Ying L. Li, Jennifer Santiago, Ann F. Hoffman, Alexandra Hicks, Gary Cavallo, Jose M. Lora, Robert Alan Goodnow, Ueli Gubler, Romyr Dominique, Achyutharao Sidduri, Nadine Tare, Qi Qiao, Grazyna Kurylko
Publikováno v:
Prostaglandinsother lipid mediators. 92(1-4)
Asthma, chronic obstructive pulmonary disease (COPD) and acute lung injury/acute respiratory distress syndrome (ALI/ARDS) are characterized by neutrophilic inflammation and elevated levels of leukotriene B4 (LTB4). However, the exact role of LTB4 pat
Autor:
Waleed, Danho, Joseph, Swistok, Wajiha, Khan, Xin-Jie, Chu, Adrian, Cheung, David, Fry, Hongmao, Sun, Grazyna, Kurylko, Leonid, Rumennik, Joseph, Cefalu, Gretchen, Cefalu, Philip, Nunn
Publikováno v:
Advances in experimental medicine and biology. 611
Autor:
David C. Fry, Joseph S. Cefalu, Gretchen Cefalu, Chu Xin-Jie, Leonid Rumennik, Hongmao Sun, Philip Nunn, Grazyna Kurylko, Wajiha Khan, Adrian Wai-Hing Cheung, Joseph Swistok, Waleed Danho
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9780387736563
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d408fb313e8f612420fcfef4aea2c273
https://doi.org/10.1007/978-0-387-73657-0_201
https://doi.org/10.1007/978-0-387-73657-0_201
Autor:
Waleed Danho, Lida Qi, Xin-Jie Chu, Vijay Gore, Li Chen, Joseph Swistok, Adrian Wai-Hing Cheung, Grazyna Kurylko, David Joseph Bartkovitz, Keith A. Yagaloff
Publikováno v:
Bioorganicmedicinal chemistry letters. 15(24)
Two libraries of hMC4R agonists, X-Y-DPhe(7)-Arg(8)-2-Nal(9)-Z-NH(2) and X-Y-DPhe(7)-Arg(8)-Trp(9)-Z-NH(2), totaling 185 peptides were prepared using Irori radiofrequency tagging technology and Argonaut Quest 210 Synthesizer, where X stands for N-cap
Autor:
Lucia Franco, Joseph Swistok, Karen Rowan, David Joseph Bartkovitz, Li Chen, Adrian Wai-Hing Cheung, Lida Qi, Xin-Jie Chu, Mitch Yeon, Keith A. Yagaloff, Grazyna Kurylko, Waleed Danho
Publikováno v:
Bioorganicmedicinal chemistry letters. 15(22)
Linear pentapeptides (Penta-cis-Apc-DPhe-Arg-Trp-Gly-NH2) containing 1-amino-4-phenylcyclohexane-1-carboxylic acid (cis-Apc) and substituted Apc are potent hMC4R agonists and they are inactive or weakly active in hMC1R, hMC3R, and hMC5R agonist assay
Autor:
Waleed Danho, Grazyna Kurylko, Adrian Wai-Hing Cheung, Joseph Swistok, Xin-Jie Chu, Keith A. Yagaloff, Li Chen, Lucia Franco
Publikováno v:
Bioorganicmedicinal chemistry letters. 13(4)
A series of pentapeptides, based on hMC4R pentapeptide agonist (Bu-His(6)-DPhe(7)-Arg(8)-Trp(9)-Gly(10)-NH(2)), was prepared in which either DPhe(7) or Trp(9) residue was systematically substituted. A number of interesting DPhe surrogates (D-Thi, D-3
Autor:
Waleed Danho, Li Chen, Keith A. Yagaloff, Lucia Franco, Karen Rowan, Grazyna Kurylko, Adrian Wai-Hing Cheung, Lida Qi, Joseph Swistok, Xin-Jie Chu, Mitch Yeon
Publikováno v:
Bioorganicmedicinal chemistry letters. 13(1)
Systematic substitution of His(6) residue using non-selective hMC4R pentapeptide agonist (Bu-His(6)-DPhe(7)-Arg(8)-Trp(9)-Gly(10)-NH(2)) as the template led to the identification of Bu-Atc(6)(2-aminotetraline-2-carboxylic acid)-DPhe(7)-Arg(8)-Trp(9)-