Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Grazisa, Rossetti"'
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
RNAs provide considerable opportunities as therapeutic agent to expand the plethora of classical therapeutic targets, from extracellular and surface proteins to intracellular nucleic acids and its regulators, in a wide range of diseases. RNA versatil
Externí odkaz:
https://doaj.org/article/09435f8de6ca4304b97b1e7dfa55c604
Autor:
Giulia Della Chiara, Federica Gervasoni, Michaela Fakiola, Chiara Godano, Claudia D’Oria, Luca Azzolin, Raoul Jean Pierre Bonnal, Giulia Moreni, Lorenzo Drufuca, Grazisa Rossetti, Valeria Ranzani, Ramona Bason, Marco De Simone, Francesco Panariello, Ivan Ferrari, Tanya Fabbris, Francesca Zanconato, Mattia Forcato, Oriana Romano, Jimmy Caroli, Paola Gruarin, Maria Lucia Sarnicola, Michelangelo Cordenonsi, Alberto Bardelli, Nicola Zucchini, Andrea Pisani Ceretti, Nicolò Maria Mariani, Andrea Cassingena, Andrea Sartore-Bianchi, Giuseppe Testa, Luca Gianotti, Enrico Opocher, Federica Pisati, Claudio Tripodo, Giuseppe Macino, Salvatore Siena, Silvio Bicciato, Stefano Piccolo, Massimiliano Pagani
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
The role of epigenetic deregulation in colorectal cancer (CRC) is not fully understood yet. Here the authors use patient-derived organoids, epigenomics and single-cell RNA-seq to reveal that YAP/TAZ are key regulators that bind to active enhancers in
Externí odkaz:
https://doaj.org/article/d24dcbd0a4754b4e8fdf6d5dd0925565
Autor:
Raffaele Iannuzzi, Grazisa Rossetti, Andrea Spitaleri, Raoul J. P. Bonnal, Massimiliano Pagani, Luca Mollica
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
The exposure to pathogens triggers the activation of adaptive immune responses through antigens bound to surface receptors of antigen presenting cells (APCs). T cell receptors (TCR) are responsible for initiating the immune response through their phy
Externí odkaz:
https://doaj.org/article/f0c899c330cb446087c442e27cead060
Autor:
Jens Geginat, Chiara Vasco, Paola Gruarin, Raoul Bonnal, Grazisa Rossetti, Ylenia Silvestri, Elena Carelli, Nadia Pulvirenti, Morena Scantamburlo, Giorgia Moschetti, Francesca Clemente, Fabio Grassi, Silvia Monticelli, Massimiliano Pagani, Sergio Abrignani
Publikováno v:
European Journal of Immunology. 53
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e83f7717c7304c34cc5974e272ec843
https://doi.org/10.1002/eji.202149775
https://doi.org/10.1002/eji.202149775
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The peculiarity of T cell is their ability to recognize an infinite range of self and foreign antigens. This ability is achieved during thymic development through a complex molecular mechanism based on somatic recombination that leads to the expressi
Externí odkaz:
https://doaj.org/article/b6ea7393ce9d4489951887d0bdcbb2c1
Autor:
Piera Calamita, Annarita Miluzio, Arianna Russo, Elisa Pesce, Sara Ricciardi, Farhat Khanim, Cristina Cheroni, Roberta Alfieri, Marilena Mancino, Chiara Gorrini, Grazisa Rossetti, Ivana Peluso, Massimiliano Pagani, Diego L Medina, Johanna Rommens, Stefano Biffo
Publikováno v:
PLoS Genetics, Vol 13, Iss 1, p e1006552 (2017)
Ribosomopathies are a family of inherited disorders caused by mutations in genes necessary for ribosomal function. Shwachman-Diamond Bodian Syndrome (SDS) is an autosomal recessive disease caused, in most patients, by mutations of the SBDS gene. SBDS
Externí odkaz:
https://doaj.org/article/6b3859ac2aa04b609c1f95feca0cba04
Autor:
Salvatore Siena, Emilia Maria Cristina Mazza, Giulia Della Chiara, Chiara Godano, Nicola Zucchini, Valeria Ranzani, Stefania Oliveto, Paola Gruarin, Jens Geginat, Roberto Bosotti, Claudia D'Oria, Elena Carelli, Pierluigi Novellis, Saveria Mazzara, Ylenia Silvestri, Marco Passaro, Alessio Amatu, Marco Alloisio, Antonio Lanzavecchia, Stefano Biffo, Giorgia Alvisi, Federica Gervasoni, Maria Lucia Sarnicola, N. Mariani, Alberto Bardelli, Ramona Bason, Jolanda Brummelman, Mariangela Lorenzo, Giulia Veronesi, Emanuela Bonoldi, Massimiliano Pagani, Daniele Prati, Enrico Opocher, Lorenzo Drufuca, Martina Martinovic, Andrea Sartore-Bianchi, Sergio Abrignani, Alessandro Giani, Marco De Simone, Enrico Lugli, Chiara Cordiglieri, Serena Curti, Grazisa Rossetti, Valeria Bevilacqua, Andrea Pisani Ceretti, Raoul J. P. Bonnal
Publikováno v:
Nature Immunology, 22, 735-745
Nature Immunology, 22, 6, pp. 735-745
Nature Immunology, 22, 6, pp. 735-745
Regulatory T (Treg) cells are a barrier for tumor immunity and a target for immunotherapy. Using single-cell transcriptomics, we found that CD4+ T cells infiltrating primary and metastatic colorectal cancer and non-small-cell lung cancer are highly e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73e12ccb9271b3892eb83d8342962f9d
https://doi.org/10.1038/s41590-021-00930-4
https://doi.org/10.1038/s41590-021-00930-4
Autor:
Maria Cristina Crosti, Marco De Simone, Saveria Mazzara, Valeria Ranzani, Jens Geginat, Grazisa Rossetti, Giorgia Moschetti, Sergio Abrignani, Paola Gruarin, Michele Chirichella, Massimiliano Pagani, Stefan Emming, Silvia Monticelli, Stefano Maglie, Chiara Vasco, Nadia Pulvirenti
Publikováno v:
European journal of immunology. 51(12)
Ex vivo gene expression and miRNA profiling of Eomes+ Tr1-like cells suggested that they represent a differentiation stage that is intermediate between Th1-cells and cytotoxic CD4+ T-cells. Several microRNAs were downregulated in Eomes+ Tr1-like cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34f7a34ec38e8c109ce65c1dfd6730fe
https://pubmed.ncbi.nlm.nih.gov/34528258
https://pubmed.ncbi.nlm.nih.gov/34528258
Autor:
Grazisa Rossetti, Paola Gruarin, Saveria Mazzara, Maria Cristina Crosti, Valeria Ranzani, Sergio Abrignani, Jens Geginat, Giorgia Moschetti, Michele Chirichella, Stefano Maglie, Massimiliano Pagani, Stefan Emming, Marco De Simone, Silvia Monticelli, Nadia Pulvirenti, Chiara Vasco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b9c7a1e77d89eb545cc438ca795c8f6
https://doi.org/10.1002/eji.202149315/v2/response1
https://doi.org/10.1002/eji.202149315/v2/response1
Autor:
Dario Besusso, Dan Felsenfeld, Valeria Ranzani, Raoul J. P. Bonnal, Samantha A. Morris, Elena Cattaneo, Massimiliano Pagani, Romina Vuono, Andrea Faedo, Paola Conforti, Marco De Simone, Roger A. Barker, Federica Gervasoni, Elena Vezzoli, Tiziana Lischetti, Xiaoling He, Maura Galimberti, Grazisa Rossetti, Vittoria Dickinson Bocchi, Jian Chen, Giulio Pavesi, Claudio Cappadona, Kenji Kamimoto, Ira Espuny-Camacho
Publikováno v:
Science
Deciphering how the human striatum develops is necessary for understanding the diseases that affect this region. To decode the transcriptional modules that regulate this structure during development, we compiled a catalog of 1116 long intergenic nonc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b7e98cb14bd6cc2e81fe26b0f21ae8f
https://doi.org/10.1126/science.abf5759
https://doi.org/10.1126/science.abf5759