Zobrazeno 1 - 10
of 169
pro vyhledávání: '"Graziella Vecchio"'
Publikováno v:
Inorganics, Vol 12, Iss 6, p 167 (2024)
Novel platinum(II) complexes of 4′-substituted terpyridine ligands were synthesized and characterized. Each complex had a different biomolecule (amine, glucose, biotin and hyaluronic acid) as a targeting motif, potentially improving therapeutic out
Externí odkaz:
https://doaj.org/article/0e7f929114c54f9598ca13294f27cc7d
Autor:
Valeria Lanza, Graziella Vecchio
Publikováno v:
Biomimetics, Vol 8, Iss 5, p 447 (2023)
Reactive oxygen species are implicated in several human diseases, including neurodegenerative disorders, cardiovascular dysfunction, inflammation, hereditary diseases, and ageing. MnIII–salen complexes are superoxide dismutase (SOD) and catalase (C
Externí odkaz:
https://doaj.org/article/b11f67dd520e41c28a11213808492df0
Publikováno v:
Molecules, Vol 28, Iss 18, p 6724 (2023)
Neurodegenerative diseases affect millions of people worldwide. The failure of the enzymatic degradation, the oxidative stress, the dyshomeostasis of metal ions, among many other biochemical events, might trigger the pathological route, but the onset
Externí odkaz:
https://doaj.org/article/fee5f0108357444a9daa2dd1e9fa5e5e
Autor:
Livia Basile, Alessandra Piccirilli, Fabrizia Brisdelli, Mariagrazia Perilli, Noemi Bognanni, Luana La Piana, Luigi Principe, Stefano Di Bella, Graziella Vecchio
Publikováno v:
Results in Chemistry, Vol 5, Iss , Pp 100986- (2023)
Antimicrobial resistance leads to the ineffectiveness of antimicrobials, hampering the ability to cure infections. Zinc-dependent metallo ß-lactamases (MBLs) producing bacteria represent a threat to public health due to limited therapeutic options.
Externí odkaz:
https://doaj.org/article/7e4c718b7354403f9cd1c80a3e007019
Autor:
Antonino Puglisi, Noemi Bognanni, Graziella Vecchio, Ece Bayir, Peter van Oostrum, Dawn Shepherd, Frances Platt, Erik Reimhult
Publikováno v:
Biomolecules, Vol 13, Iss 3, p 573 (2023)
Core–shell superparamagnetic iron oxide nanoparticles hold great promise as a theranostic platform in biological systems. Herein, we report the biological effect of multifunctional cyclodextrin-appended SPIONs (CySPION) in mutant Npc1-deficient CHO
Externí odkaz:
https://doaj.org/article/541d52a1e213425bb686f63949ef58b3
Autor:
Noemi Bognanni, Maurizio Viale, Luana La Piana, Simone Strano, Rosaria Gangemi, Cinzia Lombardo, Maria Teresa Cambria, Graziella Vecchio
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 374 (2023)
In the last years, nanoparticles based on cyclodextrins have been widely investigated for the delivery of anticancer drugs. In this work, we synthesized nanoparticles with a hyaluronic acid backbone functionalized with cyclodextrins under green condi
Externí odkaz:
https://doaj.org/article/eda421aae2304ea78ac8e76daf862dfd
Autor:
Mariacristina Nicolosi, Francesco Bellia, Maria Laura Giuffrida, Stefania Zimbone, Valentina Oliveri, Graziella Vecchio
Publikováno v:
Results in Chemistry, Vol 3, Iss , Pp 100230- (2021)
Drugs that may regulate lipid metabolism and lower cholesterol, such as statins (drugs that reduce de novo cholesterol synthesis) or cyclodextrins (that promote cholesterol removal), are currently investigated as potential therapeutics for neuronal d
Externí odkaz:
https://doaj.org/article/5780f7be407d44f98a532a4621750f0e
Autor:
Noemi Bognanni, Maurizio Viale, Alessia Distefano, Rita Tosto, Nadia Bertola, Fabrizio Loiacono, Marco Ponassi, Domenico Spinelli, Giuseppe Pappalardo, Graziella Vecchio
Publikováno v:
Molecules, Vol 26, Iss 19, p 6046 (2021)
In the few last years, nanosystems have emerged as a potential therapeutic approach to improve the efficacy and selectivity of many drugs. Cyclodextrins (CyDs) and their nanoparticles have been widely investigated as drug delivery systems. The covale
Externí odkaz:
https://doaj.org/article/6c881835cb804792b277f1d55e87fd5a
Publikováno v:
Molecules, Vol 26, Iss 6, p 1724 (2021)
Over the years, cyclodextrin uses have been widely reviewed and their proprieties provide a very attractive approach in different biomedical applications. Cyclodextrins, due to their characteristics, are used to transport drugs and have also been stu
Externí odkaz:
https://doaj.org/article/207306089a024eceb45b360f88307c88
Publikováno v:
Molecules, Vol 19, Iss 2, Pp 2299-2329 (2014)
Carnosinases are Xaa-His dipeptidases that play diverse functions throughout all kingdoms of life. Human isoforms of carnosinase (CN1 and CN2) under appropriate conditions catalyze the hydrolysis of the dipeptides carnosine (β-alanyl-L-histidine) an
Externí odkaz:
https://doaj.org/article/dade32600397406a800e645aa96a76a3