Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Graziella Griffith"'
Autor:
Jérôme Denard, Jérémy Rouillon, Thibaut Leger, Camille Garcia, Michele P. Lambert, Graziella Griffith, Christine Jenny, Jean-Michel Camadro, Luis Garcia, Fedor Svinartchouk
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 10, Iss , Pp 291-302 (2018)
Under intravenous delivery, recombinant adeno-associated vectors (rAAVs) interact with blood-borne components in ways that can critically alter their therapeutic efficiencies. We have previously shown that interaction with human galectin 3 binding pr
Externí odkaz:
https://doaj.org/article/d659829c2c974ce5a8eff3ef227507bf
Autor:
Karima Relizani, Graziella Griffith, Lucía Echevarría, Faouzi Zarrouki, Patricia Facchinetti, Cyrille Vaillend, Christian Leumann, Luis Garcia, Aurélie Goyenvalle
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 8, Iss , Pp 144-157 (2017)
Antisense oligonucleotides (AONs) hold promise for therapeutic splice-switching correction in many genetic diseases. However, despite advances in AON chemistry and design, systemic use of AONs is limited due to poor tissue uptake and sufficient thera
Externí odkaz:
https://doaj.org/article/1d94d53beb4a47d8a7a1a68df902a18f
Autor:
Valérie Robin, Graziella Griffith, John-Paul L. Carter, Christian J. Leumann, Luis Garcia, Aurélie Goyenvalle
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 7, Iss C, Pp 81-89 (2017)
Spinal muscular atrophy (SMA) is a recessive disease caused by mutations in the SMN1 gene, which encodes the protein survival motor neuron (SMN), whose absence dramatically affects the survival of motor neurons. In humans, the severity of the disease
Externí odkaz:
https://doaj.org/article/1fd64706a1484ef79eea186b22c462a9
Autor:
Camille Garcia, Thibaut Léger, Michele P. Lambert, Jérôme Denard, Christine Jenny, Jean-Michel Camadro, Fedor Svinartchouk, Luis Garcia, Graziella Griffith, Jeremy Rouillon
Publikováno v:
Molecular Therapy-Methods and Clinical Development
Molecular Therapy-Methods and Clinical Development, Nature Publishing Group, 2018, 10, pp.291-302. ⟨10.1016/j.omtm.2018.08.001⟩
Molecular Therapy-Methods & Clinical Development
Molecular Therapy-Methods & Clinical Development, 2018, 10, pp.291-302. ⟨10.1016/j.omtm.2018.08.001⟩
Molecular Therapy: Methods & Clinical Development, Vol 10, Iss, Pp 291-302 (2018)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy-Methods and Clinical Development, Nature Publishing Group, 2018, 10, pp.291-302. ⟨10.1016/j.omtm.2018.08.001⟩
Molecular Therapy-Methods & Clinical Development
Molecular Therapy-Methods & Clinical Development, 2018, 10, pp.291-302. ⟨10.1016/j.omtm.2018.08.001⟩
Molecular Therapy: Methods & Clinical Development, Vol 10, Iss, Pp 291-302 (2018)
Molecular Therapy. Methods & Clinical Development
Under intravenous delivery, recombinant adeno-associated vectors (rAAVs) interact with blood-borne components in ways that can critically alter their therapeutic efficiencies. We have previously shown that interaction with human galectin 3 binding pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70c9496cb8f8991d90fc5ec0d29c331d
https://hal.archives-ouvertes.fr/hal-02407986
https://hal.archives-ouvertes.fr/hal-02407986
Autor:
Luis Garcia, Kariem Ezzat, Claudia Bühr, Kay E. Davies, Thomas Voit, Christian J. Leumann, Arnaud Ferry, Samir El Andaloussi, Helge Amthor, Stefan Schürch, Aurélie Avril, Graziella Griffith, Aurélie Goyenvalle, Rémi Chaussenot, Arran Babbs, Cyrille Vaillend, Matthew J.A. Wood, Branislav Dugovic
Publikováno v:
Nature Medicine
Nature Medicine, Nature Publishing Group, 2015, 21 (3), pp.270-275. ⟨10.1038/nm.3765⟩
Nature Medicine, Nature Publishing Group, 2015, 21 (3), pp.270-275. ⟨10.1038/nm.3765⟩
International audience; Antisense oligonucleotides (AONs) hold promise for therapeutic correction of many genetic diseases via exon skipping, and the first AON-based drugs have entered clinical trials for neuromuscular disorders. However, despite adv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62203964de5cd28ed64a64e68a67102f
https://doi.org/10.1038/nm.3765
https://doi.org/10.1038/nm.3765
Autor:
Graziella Griffith, Guillaume Precigout, Stéphanie Lorain, Luis Garcia, Thomas Voit, Maëva Le Hir, Susanne Philippi, Arnaud Jollet, Cécile Peccate, Kamel Mamchaoui
Publikováno v:
Nucleic Acids Research
RNA-based therapeutic approaches using splice-switching oligonucleotides have been successfully applied to rescue dystrophin in Duchenne muscular dystrophy (DMD) preclinical models and are currently being evaluated in DMD patients. Although the modul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3864776e357c293a2294cc843df3e905
http://europepmc.org/articles/PMC3783188
http://europepmc.org/articles/PMC3783188
Autor:
Cyriaque Beley, Adeline Vulin, Thomas Voit, Stéphanie Lorain, Maëva Le Hir, Luis Garcia, Inès Barthélémy, Rachid Benchaouir, Yves Unterfinger, Graziella Griffith, Jean-Laurent Thibaud, Aurélie Goyenvalle, Patrick A. Dreyfus, Pierre G. Carlier, Stéphane Blot
Publikováno v:
Molecular Therapy. 20(11):2120-2133
Duchenne muscular dystrophy (DMD) is an X-linked recessive disorder resulting from lesions of the gene encoding dystrophin. These usually consist of large genomic deletions, the extents of which are not correlated with the severity of the phenotype.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e9c470871ffc1cdfe1331779839db2e
Publikováno v:
médecine/sciences
médecine/sciences, 2015, 31 (3), pp.253-256. ⟨10.1051/medsci/20153103009⟩
médecine/sciences, EDP Sciences, 2015, 31 (3), pp.253-256. ⟨10.1051/medsci/20153103009⟩
médecine/sciences, 2015, 31 (3), pp.253-256. ⟨10.1051/medsci/20153103009⟩
médecine/sciences, EDP Sciences, 2015, 31 (3), pp.253-256. ⟨10.1051/medsci/20153103009⟩
253 m/s n° 3, vol. 31, mars 2015 DOI : 10.1051/medsci/20153103009 6. Marthiens V, Rujano MA, Pennetier C, et al. Centrosome amplification causes microcephaly. Nat Cell Biol 2013 ; 15 : 731-40. 7. Lingle WL, Barrett SL, Negron VC, et al. Centrosome a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eac7f5e46f13409f787bd1237fa9e7af
https://hal.science/hal-02407963
https://hal.science/hal-02407963
Autor:
Claudine Pique, Arielle R. Rosenberg, Isabelle Le Blanc, Graziella Griffith, Lélia Delamarre, Marie-Christine Dokhélar
Publikováno v:
The Journal of Cell Biology
As for most integral membrane proteins, the intracellular transport of retroviral envelope glycoproteins depends on proper folding and oligomeric assembly in the ER. In this study, we considered the hypothesis that a panel of 22 transport-defective m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fad64c38870e87fe434937b91682229
https://doi.org/10.1083/jcb.145.1.57
https://doi.org/10.1083/jcb.145.1.57