Neuroinflammation, mitochondrial defects and neurodegeneration in mucopolysaccharidosis III type C mouse model

Autor: David Cheillan, Helena Hůlková, Lubov S. Grigoryeva, Alain Moreau, Larbi Dridi, M. Hrebicek, Brian W. Bigger, Alex Langford-Smith, Zuzana Hájková, Alexey V. Pshezhetsky, Edith Hamel, Virginie Dormoy-Raclet, Kazuhiro Ohmi, Markéta Tesařová, Eva Svobodová, Jérôme Ausseil, Carla Martins, Hana Hansikova, Yoo Choi, Fiona L. Wilkinson, Graziella DiCristo

Publikováno v: Brain-A Journal of Neurology
Brain-A Journal of Neurology, Oxford University Press (OUP), 2015, 138 (Pt 2), pp.336-55. ⟨10.1093/brain/awu355⟩

International audience; Severe progressive neurological paediatric disease mucopolysaccharidosis III type C is caused by mutations in the HGSNAT gene leading to deficiency of acetyl-CoA: alpha-glucosaminide N-acetyltransferase involved in the lysosom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44efd9ebdde328e57d42e74450ac6794
https://europepmc.org/articles/PMC4306821/

Reducing Intracortical Inhibition in the Adult Visual Cortex Promotes Ocular Dominance Plasticity

Autor: Nicoletta Berardi, Maria Spolidoro, Lamberto Maffei, Laura Cancedda, Alessandro Viegi, Tommaso Pizzorusso, Roberto De Pasquale, Graziella DiCristo, Alexey Harauzov

Experience-dependent plasticity in the cortex is often higher during short critical periods in postnatal development. The mechanisms limiting adult cortical plasticity are still unclear. Maturation of intracortical GABAergic inhibition is suggested t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e44bdc1b17cc1ceb158db5405b6462f
https://europepmc.org/articles/PMC6632513/