Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Grazia P. Nicchia"'
Autor:
Pasqua Abbrescia, Gianluca Signorile, Onofrio Valente, Claudia Palazzo, Antonio Cibelli, Grazia Paola Nicchia, Antonio Frigeri
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-12 (2024)
Abstract The water channel aquaporin-4 (AQP4) is crucial for water balance in the mammalian brain. AQP4 has two main canonical isoforms, M23, which forms supramolecular structures called Orthogonal Arrays of Particles (OAP) and M1, which does not, al
Externí odkaz:
https://doaj.org/article/ce042aa164974a94b9630f31a2697004
Autor:
Fatima Maqoud, Laura Simone, Domenico Tricarico, Giulia Maria Camerino, Marina Antonacci, Grazia Paola Nicchia
Publikováno v:
Biomedicines, Vol 12, Iss 8, p 1891 (2024)
K+ channels do play a role in cell shape changes observed during cell proliferation and apoptosis. Research suggested that the dynamics of the aggregation of Aquaporin-4 (AQP4) into AQP4-OAP isoforms can trigger cell shape changes in malignant glioma
Externí odkaz:
https://doaj.org/article/12f66bf4c8424841b9e69cdb95c9889a
Autor:
Barbara Barile, Maria Grazia Mola, Francesco Formaggio, Emanuela Saracino, Antonio Cibelli, Concetta Domenica Gargano, Guido Mogni, Antonio Frigeri, Marco Caprini, Valentina Benfenati, Grazia Paola Nicchia
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Despite of the major role of aquaporin (AQP) water channels in controlling transmembrane water fluxes, alternative ways for modulating water permeation have been proposed. In the Central Nervous System (CNS), Aquaporin-4 (AQP4) is reported to be func
Externí odkaz:
https://doaj.org/article/f250a6390eb14afe8173317e6572bd4b
Autor:
Laura Simone, Francesco Pisani, Elena Binda, Antonio Frigeri, Angelo L. Vescovi, Maria Svelto, Grazia P. Nicchia
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Background Extracellular vesicles (EVs) are membrane-enclosed particles released systemically by all cells, including tumours. Tumour EVs have been shown to manipulate their local environments as well as distal targets to sustain the tumour
Externí odkaz:
https://doaj.org/article/116bc5d577ce4525ba2e1cafa9dd446b
Autor:
Maria Grazia Mola, Emanuela Saracino, Francesco Formaggio, Arcangela Gabriella Amerotti, Barbara Barile, Tamara Posati, Antonio Cibelli, Antonio Frigeri, Claudia Palazzo, Roberto Zamboni, Marco Caprini, Grazia Paola Nicchia, Valentina Benfenati
Publikováno v:
Cellular Physiology and Biochemistry, Vol 55, Iss S1, Pp 196-212 (2021)
Externí odkaz:
https://doaj.org/article/f6ddfd84e06848708c574ae8c0a85c59
Autor:
Giacomina Brunetti, Barbara Barile, Grazia Paola Nicchia, Francesco Onorati, Giovanni Battista Luciani, Antonella Galeone
Publikováno v:
Biomedicines, Vol 11, Iss 6, p 1676 (2023)
ST2 is a member of interleukin 1 receptor family with soluble sST2 and transmembrane ST2L isoforms. The ligand of ST2 is IL-33, which determines the activation of numerous intracytoplasmic mediators following the binding with ST2L and IL-1RAcP, leadi
Externí odkaz:
https://doaj.org/article/cd211b9dffa14f32ade77650ed413ca4
Autor:
Maria Felicia Faienza, Albina Tummolo, Mauro Celli, Roberto Finocchiaro, Laura Piacente, Francesca Di Serio, Grazia Paola Nicchia, Giacomina Brunetti, Patrizia D’Eufemia
Publikováno v:
Biomedicines, Vol 11, Iss 2, p 458 (2023)
Brain-type creatine kinase (CK-BB) increases during osteoclastogenesis, with high circulating amounts in type I osteogenesis imperfecta (OI) following treatment with neridronate, a bisphosphonate able to inhibit osteoclast activity and survival. The
Externí odkaz:
https://doaj.org/article/fd02d20e5e604d13a6defe785450ed65
Autor:
Claudia Palazzo, Cinzia Buccoliero, Maria Grazia Mola, Pasqua Abbrescia, Grazia Paola Nicchia, Maria Trojano, Antonio Frigeri
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-15 (2019)
Abstract Brain water homeostasis is essential for the appropriate control of neuronal activity. Furthermore, the encasement of the central nervous system (CNS) by a hard structure, greatly limits its tolerance for the volume changes occurring with ac
Externí odkaz:
https://doaj.org/article/4a2d7a1af3604cb09b5abf0cfbf5e1f2
Autor:
Aric Huang, Wei Jin, Ahmed S. Fahad, Brooklyn K. Mussman, Grazia Paola Nicchia, Bharat Madan, Matheus Oliveira de Souza, J. Daniel Griffin, Jeffrey L. Bennett, Antonio Frigeri, Cory J. Berkland, Brandon J. DeKosky
Publikováno v:
Antibodies, Vol 11, Iss 2, p 39 (2022)
A rapid and effective method to identify disease-specific antibodies from clinical patients is important for understanding autoimmune diseases and for the development of effective disease therapies. In neuromyelitis optica (NMO), the identification o
Externí odkaz:
https://doaj.org/article/59f3a6dc89844b95ad3e0160581a8e51
Autor:
Roberta Pati, Claudia Palazzo, Onofrio Valente, Pasqua Abbrescia, Raffaella Messina, Nicoletta Concetta Surdo, Konstantinos Lefkimmiatis, Francesco Signorelli, Grazia Paola Nicchia, Antonio Frigeri
Publikováno v:
Biomolecules, Vol 12, Iss 5, p 633 (2022)
AQP4ex is a recently discovered isoform of AQP4 generated by a translational readthrough mechanism. It is strongly expressed at the astrocyte perivascular endfeet as a component of the supramolecular membrane complex, commonly called orthogonal array
Externí odkaz:
https://doaj.org/article/52fe6dc110b24da683891d19b6667439