Zobrazeno 1 - 10
of 140
pro vyhledávání: '"Grayson, Ben"'
Autor:
McLean, Samantha, Grayson, Ben, Marsh, S., Zarroug, S.H.O., Harte, Michael K., Neill, Joanna C.
Yes
Cholinergic dysfunction has been shown to be central to the pathophysiology of Alzheimer’s disease and has also been postulated to contribute to cognitive dysfunction observed in various psychiatric disorders, including schizophrenia. Defi
Cholinergic dysfunction has been shown to be central to the pathophysiology of Alzheimer’s disease and has also been postulated to contribute to cognitive dysfunction observed in various psychiatric disorders, including schizophrenia. Defi
Externí odkaz:
http://hdl.handle.net/10454/8460
Autor:
McLean, Samantha, Idris, Nagi F., Grayson, Ben, Gendle, D.F., Mackie, C., Lesage, A.S., Pemberton, D.J., Neill, Joanna C.
y
The α7 nicotinic acetylcholine receptors (nAChRs) have been highlighted as a target for cognitive enhancement in schizophrenia. Adult female hooded Lister rats received sub-chronic phencyclidine (PCP) (2mg/kg) or vehicle i.p. twice daily for
The α7 nicotinic acetylcholine receptors (nAChRs) have been highlighted as a target for cognitive enhancement in schizophrenia. Adult female hooded Lister rats received sub-chronic phencyclidine (PCP) (2mg/kg) or vehicle i.p. twice daily for
Externí odkaz:
http://hdl.handle.net/10454/8463
Autor:
McLean, Samantha, Grayson, Ben, Idris, Nagi F., Lesage, A.S., Pemberton, D.J., Mackie, C., Neill, Joanna C.
Yes
Rationale: Nicotinic α7 acetylcholine receptors (nAChRs) have been highlighted as a target for cognitive enhancement in schizophrenia. Aim: To investigate whether the deficits induced by sub-chronic phencyclidine (PCP) in reversal learning
Rationale: Nicotinic α7 acetylcholine receptors (nAChRs) have been highlighted as a target for cognitive enhancement in schizophrenia. Aim: To investigate whether the deficits induced by sub-chronic phencyclidine (PCP) in reversal learning
Externí odkaz:
http://hdl.handle.net/10454/8464
Autor:
Neill, Joanna C., Barnes, Samuel, Cook, Samantha, Grayson, Ben, Idris, Nagi F., McLean, Samantha, Snigdha, S., Rajagopal, Lakshmi, Harte, Michael K.
Yes
Cognitive deficits in schizophrenia remain an unmet clinical need. Improved understanding of the neuro- and psychopathology of these deficits depends on the availability of carefully validated animal models which will assist the development
Cognitive deficits in schizophrenia remain an unmet clinical need. Improved understanding of the neuro- and psychopathology of these deficits depends on the availability of carefully validated animal models which will assist the development
Externí odkaz:
http://hdl.handle.net/10454/8461
Autor:
McLean, Samantha, Grayson, Ben, Harris, M., Protheroe, C., Bate, S., Woolley, M.L., Neill, Joanna C.
Yes
It has been suggested that the isolation rearing paradigm models certain aspects of schizophrenia symptomatology. This study aimed to investigate whether isolation rearing impairs rats’ performance in two models of cognition: the novel obj
It has been suggested that the isolation rearing paradigm models certain aspects of schizophrenia symptomatology. This study aimed to investigate whether isolation rearing impairs rats’ performance in two models of cognition: the novel obj
Externí odkaz:
http://hdl.handle.net/10454/8486
Autor:
Brown, Jessica, Iacovelli, Luisa, Di Cicco, Gabriele, Grayson, Ben, Rimmer, Lauren, Fletcher, Jennifer, Neill, Joanna C., Wall, Mark J., Ngomba, Richard T., Harte, Michael
Publikováno v:
In Neuropharmacology 1 May 2022 208
Autor:
Grayson, Ben
Phencyclidine (PCP) is a non-competitive NMDA receptor antagonist that has been shown to induce schizophrenia-like psychotic symptoms that are clinically indistinguishable from schizophrenia in patients. When administered to rodents, PCP produces an
Externí odkaz:
http://hdl.handle.net/10454/5481
Autor:
Brown, Jessica1 (AUTHOR), Grayson, Ben1 (AUTHOR), Neill, Joanna C.1 (AUTHOR), Harte, Michael1 (AUTHOR) michael.harte@manchester.ac.uk, Wall, Mark J.2 (AUTHOR) michael.harte@manchester.ac.uk, Ngomba, Richard T.3 (AUTHOR) michael.harte@manchester.ac.uk
Publikováno v:
Cells (2073-4409). Mar2023, Vol. 12 Issue 6, p919. 23p.
Autor:
Kassab, Sarah, Begley, Paul, Church, Stephanie J., Rotariu, Sanziana M., Chevalier-Riffard, Cleo, Dowsey, Andrew W., Phillips, Alexander M., Zeef, Leo A.H., Grayson, Ben, Neill, Joanna C., Cooper, Garth J.S., Unwin, Richard D., Gardiner, Natalie J.
Publikováno v:
In Molecular Metabolism October 2019 28:107-119
Autor:
Murray, Katie N., Edye, Michelle E., Manca, Maurizio, Vernon, Anthony C., Oladipo, Joanna M., Fasolino, Victoria, Harte, Michael K., Mason, Varsha, Grayson, Ben, McHugh, Patrick C., Knuesel, Irene, Prinssen, Eric P., Hager, Reinmar, Neill, Joanna C.
Publikováno v:
In Brain Behavior and Immunity January 2019 75:48-59