Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Graves, Bridget M."'
Autor:
Singh, Sonali, Almuhanna, Yasir, Alshahrani, Mohammad Y., Lowman, Douglas W., Rice, Peter J., Gell, Chris, Ma, Zuchao, Graves, Bridget M., Jackson, Darryl, Lee, Kelly, Juarez, Rucha, Koranteng, Janice, Muntaka, Sirina, Daniel A Mitchell, Da Silva, Ana C., Hussain, Farah, Yilmaz, Gokhan
Publikováno v:
ETSU Faculty Works.
Bacterial biofilms represent a challenge to the healthcare system because of their resilience against antimicrobials and immune attack. Biofilms consist of bacterial aggregates embedded in an extracellular polymeric substance (EPS) composed of polysa
Externí odkaz:
https://dc.etsu.edu/etsu-works-2/380
Publikováno v:
ETSU Faculty Works.
The phosphoinositide 3-kinases (PI3K/Akt) dependent signaling pathway plays an important role in cardiac function, specifically cardiac contractility. We have reported that sepsis decreases myocardial Akt activation, which correlates with cardiac dys
Autor:
Noss, Ilka, Ozment, Tammy R., Graves, Bridget M., Kruppa, Michael D., Rice, Peter J., Williams, David L.
Publikováno v:
ETSU Faculty Works.
Over the last 40-yr, the majority of research on glucans has focused on β-(1→3)-glucans. Recent studies indicate that β-(1→6)-glucans may be even more potent immune modulators than β-(1→3)-glucans. Mechanisms by which β-(1→6)-glucans are
Autor:
Ozment-Skelton, Tammy A., Defluiter, Elizabeth A., Ha, Tuanzhu, Li, Chuanfu, Graves, Bridget M., Ferguson, Donald A., Schweitzer, John B., Preizsner, Johanna, Brown, Gordon D., Gordon, Siamon, Kalbfleisch, John H., Williams, David
Publikováno v:
ETSU Faculty Works.
OBJECTIVE:: To examine peripheral leukocyte Dectin-1 regulation in clinically relevant models of fungal and polymicrobial sepsis. DESIGN:: Prospective animal study. SETTING:: University medical school research laboratory. SUBJECTS:: Age, weight, and
Externí odkaz:
https://dc.etsu.edu/etsu-works/17103
Autor:
Wondergem, Robert, Graves, Bridget M., Ozment-Skelton, Tammy R., Li, Chuanfu, Williams, David L.
Publikováno v:
ETSU Faculty Works.
Lipopolysaccharide (LPS) has been implicated in sepsis-mediated heart failure and chronic cardiac myopathies. We determined that LPS directly and reversibly affects cardiac myocyte function by altering regulation of intracellular Ca2+ concentration (
Externí odkaz:
https://dc.etsu.edu/etsu-works/16816
Autor:
Burt, Rees, Graves, Bridget M., Gao, Ming, Li, Chaunfu, Williams, David L., Fregoso, Santiago P., Hoover, Donald B., Li, Ying, Wright, Gary L., Wondergem, Robert
Publikováno v:
ETSU Faculty Works.
It is well established that intracellular calcium ([Ca2+]i) controls the inotropic state of the myocardium, and evidence mounts that a "Ca2+ clock" controls the chronotropic state of the heart. Recent findings describe a calcium-activated nonselectiv
Externí odkaz:
https://dc.etsu.edu/etsu-works/14337
Publikováno v:
ETSU Faculty Works.
Sepsis has deleterious effects on cardiac function including reduced contractility. We have shown previously that lipopolysaccharides (LPS) directly affect HL-1 cardiac myocytes by inhibiting Ca2+ regulation and by impairing pacemaker "funny" current
Externí odkaz:
https://dc.etsu.edu/etsu-works/16098
Autor:
Burt, Rees, Graves, Bridget M., Gao, Ming, Li, Chaunfu, Williams, David L., Fregoso, Santiago P., Hoover, Donald B., Li, Ying, Wright, Gary L., Wondergem, Robert
Publikováno v:
ETSU Faculty Works.
It is well established that intracellular calcium ([Ca2+]i) controls the inotropic state of the myocardium, and evidence mounts that a "Ca2+ clock" controls the chronotropic state of the heart. Recent findings describe a calcium-activated nonselectiv
Externí odkaz:
https://dc.etsu.edu/etsu-works/14868
Publikováno v:
Journal of Biomedical Science, Vol 19, Iss 1, p 59 (2012)
Abstract The phosphoinositide 3-kinases (PI3K/Akt) dependent signaling pathway plays an important role in cardiac function, specifically cardiac contractility. We have reported that sepsis decreases myocardial Akt activation, which correlates with ca
Externí odkaz:
https://doaj.org/article/12beaae766334d358e6663c92252f56c
Autor:
Graves, Bridget M1, Simerly, Thomas2, Chuanfu Li1, Williams, David L1, Wondergem, Robert2,3 wonderge@etsu.edu
Publikováno v:
Journal of Biomedical Science. 2012, Vol. 19 Issue 1, p59-67. 9p. 6 Diagrams, 4 Charts.