Zobrazeno 1 - 10
of 913
pro vyhledávání: '"Grauel A"'
Publikováno v:
Value Contrasts and Consensus in Present-Day Europe. 15:19-43
Autor:
Antonia Grauel, Jan Kägi, Tim Rasmussen, Iryna Makarchuk, Sabrina Oppermann, Aurélien F. A. Moumbock, Daniel Wohlwend, Rolf Müller, Frederic Melin, Stefan Günther, Petra Hellwig, Bettina Böttcher, Thorsten Friedrich
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Terminal bd oxidases endow bacterial pathogens with resistance to cellular stressors. The authors report the structure of E. coli bd-II type oxidase with the bound inhibitor aurachin D, providing a structural basis for the design of specifically bind
Externí odkaz:
https://doaj.org/article/20085e0d8d9048149ac18c44b6585ba4
Autor:
Emily Lee, Sarah Szvetecz, Ryan Polli, Angelo Grauel, Jayson Chen, Joyce Judge, Smita Jaiswal, Rie Maeda, Stephanie Schwartz, Bernd Voedisch, Mateusz Piksa, Chietara Japutra, Lingheswar Sadhasivam, Yiqin Wang, Ana Carrion, Sinan Isim, Jinsheng Liang, Thomas Nicholson, Hong Lei, Qing Fang, Michelle Steinkrauss, Dana Walker, Joel Wagner, Viviana Cremasco, Hui Qin Wang, Giorgio G. Galli, Brian Granda, Keith Mansfield, Quincey Simmons, Andrew Anh Nguyen, Nicole Vincent Jordan
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract High-grade serous ovarian cancers (HGSOC) represent the most common subtype of ovarian malignancies. Due to the frequency of late-stage diagnosis and high rates of recurrence following standard of care treatments, novel therapies are needed
Externí odkaz:
https://doaj.org/article/43b3a91fdd2f4465a835393a7f3b1b6b
Autor:
Dunbar, Anthony W.1 adunbar@dom.edu, McFarland, Rebekah1 mcfarebe@my.dom.edu, Grauel, Elizabeth2 grauele1@udayton.edu
Publikováno v:
Journal of Education for Library & Information Science. Jul2024, Vol. 65 Issue 3, p240-259. 20p.
Autor:
Ye Wang, Morvarid Mohseni, Angelo Grauel, Javier Estrada Diez, Wei Guan, Simon Liang, Jiyoung Elizabeth Choi, Minying Pu, Dongshu Chen, Tyler Laszewski, Stephanie Schwartz, Jane Gu, Leandra Mansur, Tyler Burks, Lauren Brodeur, Roberto Velazquez, Steve Kovats, Bhavesh Pant, Giri Buruzula, Emily Deng, Julie T. Chen, Farid Sari-Sarraf, Christina Dornelas, Malini Varadarajan, Haiyan Yu, Chen Liu, Joanne Lim, Huai-Xiang Hao, Xiaomo Jiang, Anthony Malamas, Matthew J. LaMarche, Felipe Correa Geyer, Margaret McLaughlin, Carlotta Costa, Joel Wagner, David Ruddy, Pushpa Jayaraman, Nathaniel D. Kirkpatrick, Pu Zhang, Oleg Iartchouk, Kimberly Aardalen, Viviana Cremasco, Glenn Dranoff, Jeffrey A. Engelman, Serena Silver, Hongyun Wang, William D. Hastings, Silvia Goldoni
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-23 (2021)
Abstract SHP2 is a ubiquitous tyrosine phosphatase involved in regulating both tumor and immune cell signaling. In this study, we discovered a novel immune modulatory function of SHP2. Targeting this protein with allosteric SHP2 inhibitors promoted a
Externí odkaz:
https://doaj.org/article/aeca1d5b6b344aeabcc21b726ae4f617
Autor:
Angelo L. Grauel, Beverly Nguyen, David Ruddy, Tyler Laszewski, Stephanie Schwartz, Jonathan Chang, Julie Chen, Michelle Piquet, Marc Pelletier, Zheng Yan, Nathaniel D. Kirkpatrick, Jincheng Wu, Antoine deWeck, Markus Riester, Matt Hims, Felipe Correa Geyer, Joel Wagner, Kenzie MacIsaac, James Deeds, Rohan Diwanji, Pushpa Jayaraman, Yenyen Yu, Quincey Simmons, Shaobu Weng, Alina Raza, Brian Minie, Mirek Dostalek, Pavitra Chikkegowda, Vera Ruda, Oleg Iartchouk, Naiyan Chen, Raphael Thierry, Joseph Zhou, Iulian Pruteanu-Malinici, Claire Fabre, Jeffrey A. Engelman, Glenn Dranoff, Viviana Cremasco
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Understanding the tumor microenviroment is important before it can be exploited therapeutically. Here, the authors use single cell sequencing to study stromal cells in mouse tumors and identify a subset of interferon-licensed cancer associated fibrob
Externí odkaz:
https://doaj.org/article/55eb6b2ee746490ba919c1fb7bbcfb1d
Autor:
Guadalupe J Jasso, Alok Jaiswal, Mukund Varma, Tyler Laszewski, Angelo Grauel, Abdifatah Omar, Nilsa Silva, Glenn Dranoff, Jeffrey A Porter, Keith Mansfield, Viviana Cremasco, Aviv Regev, Ramnik J Xavier, Daniel B Graham
Publikováno v:
PLoS Biology, Vol 20, Iss 1, p e3001532 (2022)
Chronic inflammation is often associated with the development of tissue fibrosis, but how mesenchymal cell responses dictate pathological fibrosis versus resolution and healing remains unclear. Defining stromal heterogeneity and identifying molecular
Externí odkaz:
https://doaj.org/article/56ff678867654cd1ac04c58c9f8ec4d5
Autor:
Patzke, Christopher, Brockmann, Marisa M., Dai, Jinye, Gan, Kathlyn J., Grauel, M. Katharina, Fenske, Pascal, Liu, Yu, Acuna, Claudio, Rosenmund, Christian, Südhof, Thomas C.
Publikováno v:
In Cell 3 October 2019 179(2):498-513
Autor:
Pascal Fenske, M. Katharina Grauel, Marisa M. Brockmann, Anja L. Dorrn, Thorsten Trimbuch, Christian Rosenmund
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Abstract Recently developed technology to differentiate induced pluripotent stem cells (iPSCs) into human induced neurons (iNs) provides an exciting opportunity to study the function of human neurons. However, functional characterisations of iNs have
Externí odkaz:
https://doaj.org/article/a865c8d717e04bdcb85579ff705a28ef
Autor:
Rohan Diwanji, Neil A. O'Brien, Jiyoung E. Choi, Beverly Nguyen, Tyler Laszewski, Angelo L. Grauel, Zheng Yan, Xin Xu, Jincheng Wu, David A. Ruddy, Michelle Piquet, Marc R. Pelletier, Alexander Savchenko, LaSalette Charette, Vanessa Rodrik-Outmezguine, Jason Baum, John M. Millholland, Connie C. Wong, Anne-Marie Martin, Glenn Dranoff, Iulian Pruteanu-Malinici, Viviana Cremasco, Catherine Sabatos-Peyton, Pushpa Jayaraman
Publikováno v:
Cancer Immunology Research. :OF1-OF15
High levels of IL1β can result in chronic inflammation, which in turn can promote tumor growth and metastasis. Inhibition of IL1β could therefore be a promising therapeutic option in the treatment of cancer. Here, the effects of IL1β blockade indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2113f881dcef8aa2a9477568837b9bec
https://doi.org/10.1158/2326-6066.cir-22-0290
https://doi.org/10.1158/2326-6066.cir-22-0290