Identification of the Neoaspergillic Acid Biosynthesis Gene Cluster by Establishing an In Vitro CRISPR-Ribonucleoprotein Genetic System in Aspergillus melleus .

Autor: Yuan B; Department of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Southern California, Los Angeles, California 90089, United States., Grau MF; Department of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Southern California, Los Angeles, California 90089, United States., Murata RM; Department of Foundational Sciences, School of Dental Medicine, East Carolina University, Greenville, North Carolina 27834, United States., Torok T; Ecology Department, Lawrence Berkley National Laboratory, Berkeley, California 94720, United States., Venkateswaran K; Jet Propulsion Laboratory, California Institute of Technology, Pasadena, California 91109, United States., Stajich JE; Department of Microbiology and Plant Pathology, University of California Riverside, Riverside, California 92521, United States., Wang CCC; Department of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Southern California, Los Angeles, California 90089, United States.; Department of Chemistry, University of Southern California, Dornsife College of Letters, Arts, and Sciences, Los Angeles, California 90089, United States.

Publikováno v: ACS omega [ACS Omega] 2023 May 01; Vol. 8 (19), pp. 16713-16721. Date of Electronic Publication: 2023 May 01 (Print Publication: 2023).

Hybrid Transcription Factor Engineering Activates the Silent Secondary Metabolite Gene Cluster for (+)-Asperlin in Aspergillus nidulans.

Autor: Grau MF; Department of Pharmacology and Pharmaceutical Sciences , School of Pharmacy, University of Southern California , Los Angeles , California 90089 , United States., Entwistle R; Department of Molecular Biosciences , University of Kansas , Lawrence , Kansas 66045 , United States., Chiang YM; Department of Pharmacology and Pharmaceutical Sciences , School of Pharmacy, University of Southern California , Los Angeles , California 90089 , United States.; Department of Pharmacy , Chia Nan University of Pharmacy and Science , Tainan City 71710 , Taiwan., Ahuja M; Department of Molecular Biosciences , University of Kansas , Lawrence , Kansas 66045 , United States., Oakley CE; Department of Molecular Biosciences , University of Kansas , Lawrence , Kansas 66045 , United States., Akashi T; Division of OMICS Analysis, Center for Neurological Diseases and Cancer , Nagoya University Graduate School of Medicine , Nagoya 466-8550 , Japan., Wang CCC; Department of Pharmacology and Pharmaceutical Sciences , School of Pharmacy, University of Southern California , Los Angeles , California 90089 , United States.; Department of Chemistry, Dornsife College of Letters, Arts, and Sciences , University of Southern California , Los Angeles , California 90089 , United States., Todd RB; Department of Plant Pathology , Kansas State University , 4024 Throckmorton Plant Sciences Center , Manhattan , Kansas 66506 , United States., Oakley BR; Department of Molecular Biosciences , University of Kansas , Lawrence , Kansas 66045 , United States.

Publikováno v: ACS chemical biology [ACS Chem Biol] 2018 Nov 16; Vol. 13 (11), pp. 3193-3205. Date of Electronic Publication: 2018 Oct 29.