Zobrazeno 1 - 10
of 718
pro vyhledávání: '"Gratteri P"'
Autor:
Margherita Pallocci, Pierluigi Passalacqua, Claudia Zanovello, Luca Coppeta, Cristiana Ferrari, Filippo Milano, Santo Gratteri, Nicola Gratteri, Michele Treglia
Publikováno v:
Forensic Sciences, Vol 4, Iss 3, Pp 277-288 (2024)
Complex suicides refer to using two or more suicide modes. In the literature, complex suicides are distinguished into planned and unplanned. Using multiple methods is related to ensuring a fatal result or because the first method appears too painful,
Externí odkaz:
https://doaj.org/article/6c159cf9bbc84d2596848d506b784ba6
Autor:
Alessio Nocentini, Anna Di Porzio, Alessandro Bonardi, Carla Bazzicalupi, Andrea Petreni, Tarita Biver, Silvia Bua, Simona Marzano, Jussara Amato, Bruno Pagano, Nunzia Iaccarino, Stefano De Tito, Stefano Amente, Claudiu T. Supuran, Antonio Randazzo, Paola Gratteri
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 39, Iss 1 (2024)
A novel class of compounds designed to hit two anti-tumour targets, G-quadruplex structures and human carbonic anhydrases (hCAs) IX and XII is proposed. The induction/stabilisation of G-quadruplex structures by small molecules has emerged as an antic
Externí odkaz:
https://doaj.org/article/72c74b1aaac342a2836205f0ff910408
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 39, Iss 1 (2024)
AbstractA novel series of hydantoins incorporating phthalimides has been synthesised by condensation of activated phthalimides with 1-aminohydantoin and investigated for their inhibitory activity against a panel of human (h) carbonic anhydrase (CA, E
Externí odkaz:
https://doaj.org/article/e4dede48e0c541abb1dbd975df0400c2
Autor:
Bocchi, Giovanni, Frosini, Patrizio, Micheletti, Alessandra, Pedretti, Alessandro, Gratteri, Carmen, Lunghini, Filippo, Beccari, Andrea Rosario, Talarico, Carmine
Nowadays there is a big spotlight cast on the development of techniques of explainable machine learning. Here we introduce a new computational paradigm based on Group Equivariant Non-Expansive Operators, that can be regarded as the product of a risin
Externí odkaz:
http://arxiv.org/abs/2202.00451
Autor:
Barbara Cagli, MD, PhD, Marco Gratteri, MD, Andrea A. Cimmino, MD, Francesco Sofo, MD, Carlo Mirra, MD, Luca Savani, MD, Iside Vignapiano, MD, Annalisa Cogliandro, MD, PhD, Giovanni F. Marangi, MD, PhD, Paolo Persichetti, MD, PhD
Publikováno v:
Plastic and Reconstructive Surgery, Global Open, Vol 12, Iss 3, p e5676 (2024)
Summary:. Breast reduction is one of the most required plastic surgery procedures worldwide, improving significantly the quality of life for patients with macromastia and gigantomachia. Despite various proposed approaches aiming to yield more stable
Externí odkaz:
https://doaj.org/article/2ae83765b38f4cdf8110ad4cf5be60f3
Autor:
Caterina Battaglia, Francesco Manti, Daniela Mazzuca, Antonio Cutruzzolà, Marcello Della Corte, Fiorella Caputo, Santo Gratteri, Domenico Laganà
Publikováno v:
Frontiers in Health Services, Vol 4 (2024)
PurposeThe coronavirus pandemic (COVID-19) significantly impacted the global economy and health. Italy was one of the first and most affected countries. The objective of our study was to assess the impact of the pandemic and the vaccination campaign
Externí odkaz:
https://doaj.org/article/8904cd0322c6451882cc1881dc5ebc38
Discovery of the first-in-class potent and isoform-selective human carbonic anhydrase III inhibitors
Autor:
Simone Giovannuzzi, Alessandro Bonardi, Paola Gratteri, Alessio Nocentini, Claudiu T. Supuran
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
Considering the unrecognised physio-pathological role of human carbonic anhydrase III (hCA III), a structure-based drug design was set up to identify the first-in-class potent and selective inhibitors of this neglected isoform. hCA III targeting was
Externí odkaz:
https://doaj.org/article/0d1cac7dbab14fcaad0a75ab557ea796
Autor:
Waleed A. Badawi, Mahmoud Rashed, Alessio Nocentini, Alessandro Bonardi, Mohammad M. Abd-Alhaseeb, Sara T. Al-Rashood, Giri Babu Veerakanellore, Taghreed A. Majrashi, Eslam B. Elkaeed, Bahaa Elgendy, Paola Gratteri, Claudiu T. Supuran, Wagdy M. Eldehna, Mohamed Elagawany
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
Multiple inhibitions of CA, COX-2 and 5-LOX enzymes has been recognised as a useful strategy for the development of anti-inflammatory drugs that can avoid the disadvantages of using NSAIDs alone. Here, we report new pyridazine-based sulphonamides (5a
Externí odkaz:
https://doaj.org/article/7a426bc58f904cfda5b2a8731ea107d2
Autor:
Nora Astrain-Redin, Niccolò Paoletti, Daniel Plano, Alessandro Bonardi, Paola Gratteri, Andrea Angeli, Carmen Sanmartin, Claudiu T. Supuran
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
In the relentless search for new cancer treatments, organoselenium compounds, and carbonic anhydrase (CA) inhibitors have emerged as promising drug candidates. CA isoforms IX and XII are overexpressed in many types of cancer, and their inhibition is
Externí odkaz:
https://doaj.org/article/7da47668284745f78dcb2e9ab0e624ab
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