Výsledky vyhledávání - "Grattan Woodson"

Skeletal Histomorphometry in Subjects on Teriparatide or Zoledronic Acid Therapy (SHOTZ) Study: A Randomized Controlled Trial

Autor: David L. Kendler, Grattan Woodson, Hua Zhou, Christopher Recknor, David W. Dempster, Robert R. Recker, Robert Lindsay, D. Sudhaker Rao, E. Michael Lewiecki, Kathleen A. Taylor, Michael A. Bolognese, Boris Janos, Valerie A Ruff, Paul D. Miller, Xiaohai Wan, Jacques P. Brown, Neil Binkley, David A. Hanley

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 97:2799-2808

Recent studies on the mechanism of action (MOA) of bone-active drugs have rekindled interest in how to present and interpret dynamic histomorphometric parameters of bone remodeling.We compared the effects of an established anabolic agent, teriparatid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3317498cd9ffb4c9893bcc068982350
https://doi.org/10.1210/jc.2012-1262

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Rechallenge of patients who had discontinued alendronate therapy because of upper gastrointestinal symptoms

Autor: John Yates, Paul D. Miller, Barbara Mako, Mary E. Smith, Angelo A. Licata, Joanne Palmisano, Lixia Wang, Mary E. Melton, Grattan Woodson, Mark P. Ettinger

Publikováno v: Clinical Therapeutics. 22:1433-1442

Background: There have been reports from physicians in clinical practice that up to 30% of patients taking bisphosphonate therapy develop upper gastrointestinal (UGI) symptoms, many or most of which they assume to be related to the drug. However, in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f485ca130f4316214321e9e24875a205
https://doi.org/10.1016/s0149-2918(00)83042-8

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Effect of Abaloparatide vs Placebo on New Vertebral Fractures in Postmenopausal Women With Osteoporosis

Autor: Paul D, Miller, Gary, Hattersley, Bente Juel, Riis, Gregory C, Williams, Edith, Lau, Luis Augusto, Russo, Peter, Alexandersen, Cristiano A F, Zerbini, Ming-yi, Hu, Alan G, Harris, Lorraine A, Fitzpatrick, Felicia, Cosman, Claus, Christiansen, Grattan, Woodson

Publikováno v: JAMA. 316:722

Importance Additional therapies are needed for prevention of osteoporotic fractures. Abaloparatide is a selective activator of the parathyroid hormone type 1 receptor. Objective To determine the efficacy and safety of abaloparatide, 80 μg, vs placeb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba920d78781a75d4ba28696c4b90ba6f
https://doi.org/10.1001/jama.2016.11136

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Bone histomorphometric changes after cyclic therapy with phosphate and etidronate disodium in women with postmenopausal osteoporosis

Autor: Grattan Woodson, Paul D. Miller, Nelson B. Watts, Susan M. Ott, William E. Huffer

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 78:968-972

The purpose of this study was to examine bone histomorphometry before and after 2 yr of a double blind trial of etidronate to determine whether etidronate was associated with the development of osteomalacia and to clarify the mechanism of action. Six

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6c3f00c0c9e7e46d49be28ab9cbbdba
https://doi.org/10.1210/jcem.78.4.8157728

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Denosumab densitometric changes assessed by quantitative computed tomography at the spine and hip in postmenopausal women with osteoporosis

Autor: Stefan Goemaere, Andrea Wang, Christopher Recknor, Maria Luisa Brandi, Chui Kin Yuen, Michael A. Bolognese, Sigtas Stonkus, Grattan Woodson, Edward Franek, Arne Hoiseth, David L. Kendler, Cesar Libanati, Jose R. Zanchetta, Michael R. McClung, Jacques P. Brown

Publikováno v: Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry. 16(2)

FREEDOM was a phase 3 trial in 7808 women aged 60–90 yr with postmenopausal osteoporosis. Subjects received placebo or 60 mg denosumab subcutaneously every 6 mo for 3 yr in addition to daily calcium and vitamin D. Denosumab significantly decreased

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3b20beb41ce352c4655c075b64a1301
https://pubmed.ncbi.nlm.nih.gov/22572531

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Effects of denosumab on bone histomorphometry: the FREEDOM and STAND studies

Autor: Javier San Martin, Ian R. Reid, Astrid Fahrleitner-Pammer, Rachel B. Wagman, Katre Maasalu, Henry G. Bone, Paul D. Miller, Grattan Woodson, Ivo Valter, David L. Kendler, Beiying Ding, Michael A. Bolognese, Jacques P. Brown, Michael S. Ominsky, David W. Dempster

Publikováno v: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 25(10)

Denosumab, a human monoclonal antibody against RANKL, reversibly inhibits osteoclast-mediated bone resorption and has been developed for use in osteoporosis. Its effects on bone histomorphometry have not been described previously. Iliac crest bone bi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::243ea0094ea18b78c52eb723bee8edcd
https://pubmed.ncbi.nlm.nih.gov/20533525

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Effects of bazedoxifene on BMD and bone turnover in postmenopausal women: 2-yr results of a randomized, double-blind, placebo-, and active-controlled study

Autor: Hans Christian Hoeck, Arkadi Chines, Paul D. Miller, Claus Christiansen, David L. Kendler, Ginger D. Constantine, E. Michael Lewiecki, Amy B. Levine, Pierre D. Delmas, Grattan Woodson

Publikováno v: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 23(4)

Osteoporosis is an increasingly common health concern in postmenopausal women. In a 2-yr phase III study, bazedoxifene prevented bone loss, reduced bone turnover, and was well tolerated in early postmenopausal women with normal or low BMD. Introducti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::603ccdcb9695a647eb659de93802e25a
https://pubmed.ncbi.nlm.nih.gov/18072873

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Dual X-ray absorptiometry T-score concordance and discordance between the hip and spine measurement sites

Autor: Grattan Woodson

Publikováno v: Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry. 3(4)

T-score discordance is observed when the difference between the hip and spine are sufficient to result in the two measurement sites falling into two different diagnoses as defined by the World Health Organization (WHO) classification system. This art

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3713095d66b3efc6e94cccfbe6bbe1f5
https://pubmed.ncbi.nlm.nih.gov/11175911

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