Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Gratien G. Prefontaine"'
Autor:
Shabnam Massah, Robert Hollebakken, Mark P Labrecque, Addie M Kolybaba, Timothy V Beischlag, Gratien G Prefontaine
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97535 (2014)
Regulatory elements for the mouse growth hormone (GH) gene are located distally in a putative locus control region (LCR) in addition to key elements in the promoter proximal region. The role of promoter DNA methylation for GH gene regulation is not w
Externí odkaz:
https://doaj.org/article/4b5386e07cc14aa6bf5b1615ae59c524
Autor:
Mark P Labrecque, Mandeep K Takhar, Julienne M Jagdeo, Kevin J Tam, Christina Chiu, Te-Yu Wang, Gratien G Prefontaine, Michael E Cox, Timothy V Beischlag
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99214 (2014)
Localized hypoxia in solid tumors activates transcriptional programs that promote the metastatic transformation of cells. Like hypoxia-inducible hyper-vascularization, loss of the retinoblastoma protein (Rb) is a trait common to advanced stages of tu
Externí odkaz:
https://doaj.org/article/e276625e12064928ae0b5aed567d1aed
Publikováno v:
BMC Genetics, Vol 21, Iss 1, Pp 1-10 (2020)
BMC Genetics
BMC Genetics
Background DNA methylation is an epigenetic modification that mainly repress expression of genes essential during embryogenesis and development. There are key ATPase-dependent enzymes that read or write DNA methylation to remodel chromatin and regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec810266bda20aa34961f56bf97613f2
https://doi.org/10.1186/s12863-020-0809-x
https://doi.org/10.1186/s12863-020-0809-x
Autor:
Mark P Labrecque, Mandeep K Takhar, Brett D Hollingshead, Gratien G Prefontaine, Gary H Perdew, Timothy V Beischlag
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29545 (2012)
The activated AHR/ARNT complex (AHRC) regulates the expression of target genes upon exposure to environmental contaminants such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Importantly, evidence has shown that TCDD represses estrogen receptor (ER)
Externí odkaz:
https://doaj.org/article/15c17945b68e44948544a812e0705ebb
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1689
Chromatin immunoprecipitation (ChIP) exploits the specific interactions between DNA and DNA-associated proteins. It can be used to examine a wide range of experimental parameters. A number of proteins bound at the same genomic location can identify a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::daeb206c66a11fd704fd8e5ab077b3e7
https://pubmed.ncbi.nlm.nih.gov/29027168
https://pubmed.ncbi.nlm.nih.gov/29027168
Publikováno v:
Chromatin Immunoprecipitation ISBN: 9781493973798
Chromatin immunoprecipitation (ChIP) exploits the specific interactions between DNA and DNA-associated proteins. It can be used to examine a wide range of experimental parameters. A number of proteins bound at the same genomic location can identify a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::246c0c98070a3d5623a5f22491ea50b3
https://doi.org/10.1007/978-1-4939-7380-4_9
https://doi.org/10.1007/978-1-4939-7380-4_9
Publikováno v:
Journal of Human Genetics. 59:332-336
Imprinted genes have been posited to have important roles in human brain development and cognition, but their effects in nonclinical populations have yet to be investigated. Single-nucleotide polymorphisms (SNPs) of the imprinted gene LRRTM1 have pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ae5cc430f601dc44ffb9f25afc7cfdb
https://doi.org/10.1038/jhg.2014.30
https://doi.org/10.1038/jhg.2014.30
Autor:
Robert D. Burke, Nikolai Dechev, Hadi Esmaeilsabzali, Shabnam Massah, Gratien G. Prefontaine, Kelly Sakaki, Edward J. Park
Publikováno v:
IEEE Transactions on Biomedical Engineering. 60:3113-3123
Single cell electroporation (SCE), via microcapillary, is an effective method for molecular, transmembrane transport used to gain insight on cell processes with minimal preparation. Although possessing great potential, SCE is difficult to execute and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97d7dbaa293e70dde587afe8417ebe33
https://doi.org/10.1109/tbme.2013.2268387
https://doi.org/10.1109/tbme.2013.2268387
Autor:
Gratien G. Prefontaine, Addie Kolybaba, Kevin J. Tam, Timothy V. Beischlag, Corey T. Watson, Shabnam Massah, Felix Breden
Publikováno v:
Vision Research. 51(21-22):2295-2303
Vertebrate opsin genes often occur in sets of tandem duplicates, and their expression varies developmentally and in response to environmental cues. We previously identified two highly conserved regions upstream of the long-wave sensitive opsin (LWS)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da60145459d6cdd87d8e700ef0fe2948
Autor:
Michael G. Rosenfeld, Thorsten Cramer, Kasey R. Hutt, Xiaoyan Zhu, Esperanza Nunez, Victoria V. Lunyak, Lluis Montoliu, Ángel García-Díaz, Yun C. Yung, Bong-Gun Ju, Christopher K. Glass, Kenneth A. Ohgi, R. Roy, Gratien G. Prefontaine
Publikováno v:
Science. 317:248-251
The temporal and spatial regulation of gene expression in mammalian development is linked to the establishment of functional chromatin domains. Here, we report that tissue-specific transcription of a retrotransposon repeat in the murine growth hormon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::462842c9c963b1cbc25f73f4a6f9e907
https://doi.org/10.1126/science.1140871
https://doi.org/10.1126/science.1140871