Zobrazeno 1 - 10
of 8 005
pro vyhledávání: '"Granzyme-B"'
Autor:
Won-Dong Kim, Don D. Sin
Publikováno v:
COPD, Vol 21, Iss 1, Pp 1-11 (2024)
AbstractChronic obstructive pulmonary disease (COPD) is caused by smoking, but only a small proportion of smokers have disease severe enough to develop COPD. COPD is not always progressive. The question then arises as to what explains the different t
Externí odkaz:
https://doaj.org/article/a73fc2ca4d1947a69109af353104d22a
Publikováno v:
陆军军医大学学报, Vol 46, Iss 17, Pp 1959-1968 (2024)
Objective To investigate the feasibility of granzyme B (GB) promoter-controlled ferritin heavy chain (FTH1) reporter gene expression for monitoring the activation status of chimeric antigen receptor T cells (CAR-T) by magnetic resonance imaging (MRI)
Externí odkaz:
https://doaj.org/article/b92548c2f9ce47429828cc255be42a20
Autor:
Porntida Wattanakull, Dakrong Pissuwan
Publikováno v:
Nano Select, Vol 5, Iss 11, Pp n/a-n/a (2024)
ABSTRACT Cell encapsulation can protect cells from the host immune system. It is well‐known that cytotoxic T lymphocytes (CTLs) can destroy cancer cells. In this study, we individually encapsulated CTLs in a cationic polyelectrolyte in combination
Externí odkaz:
https://doaj.org/article/d3db62ce68634f41aee694616f7a684f
Publikováno v:
Journal of Inflammation Research, Vol Volume 17, Pp 4505-4523 (2024)
Xu Yang,1,* Jianwei Wu,1,* Longlong Fan,2 Binghua Chen,3 Shiqiang Zhang,4 Wenzhong Zheng1 1Department of Urology, Fujian Medical University Union Hospital, Fuzhou, People’s Republic of China; 2Department of Urology, The Eighth Affiliated Ho
Externí odkaz:
https://doaj.org/article/d5491e10b8d04b18b33f7c129c81be39
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Natural killer (NK) cells are closely associated with malignant tumor progression and metastasis. However, studies on their relevance in colorectal cancer (CRC) are limited. We aimed to comprehensively analyze the absolute counts, phenotypes
Externí odkaz:
https://doaj.org/article/6ecaab6f7e0d4ccd8aa28b0f6c0c178e
Publikováno v:
Case Reports in Dermatology, Vol 16, Iss 1, Pp 116-122 (2024)
Introduction: Anti-PD-1 immunotherapies enhance T-cell responses against tumor cells by blocking the interaction between PD-1 and its ligand, PD-L1. While these therapies offer significant benefits in treating various malignancies, they can also lead
Externí odkaz:
https://doaj.org/article/d9ddab1b96014fc38f4d71c9a40e216b
Akademický článek
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Akademický článek
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Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Background Antibody drug conjugates (ADCs) constitute a promising class of targeted anti-tumor therapeutics that harness the selectivity of monoclonal antibodies with the potency of cytotoxic drugs. ADC development is best suited to initiall
Externí odkaz:
https://doaj.org/article/8685e81748f54f4d91d70ca7f5c59c64
Publikováno v:
Diagnostic Pathology, Vol 19, Iss 1, Pp 1-9 (2024)
Abstract Background Cytotoxic lymphocytes (CLs) express potent toxins, including perforin (P) and granzyme-B (G), which brings about target cell death. The purpose of this study was to evaluate the killing capacity of tumor-infiltrating CLs by means
Externí odkaz:
https://doaj.org/article/9ec1fb4a843b4b9cae173793a3461916