Improved overall survival in patients with high-grade serous ovarian cancer is associated with CD16a+ immunologic neighborhoods containing NK cells, T cells and macrophages.

Autor: Nersesian S; Department of Microbiology and Immunology, Dalhousie University, Halifax, NS, Canada.; Beatrice Hunter Cancer Research Institute, Halifax, NS, Canada., Arseneau RJ; Beatrice Hunter Cancer Research Institute, Halifax, NS, Canada.; Department of Pathology, Dalhousie University, Halifax, NS, Canada., Mejia JP; Department of Microbiology and Immunology, Dalhousie University, Halifax, NS, Canada.; Beatrice Hunter Cancer Research Institute, Halifax, NS, Canada., Lee SN; Department of Microbiology and Immunology, Dalhousie University, Halifax, NS, Canada.; Beatrice Hunter Cancer Research Institute, Halifax, NS, Canada., Westhaver LP; Department of Pathology, Dalhousie University, Halifax, NS, Canada., Griffiths NW; Department of Pathology, Dalhousie University, Halifax, NS, Canada., Grantham SR; Beatrice Hunter Cancer Research Institute, Halifax, NS, Canada., Meunier L; Centre de recherche du Centre hospitalier de l'Université de Montréal and Institut du cancer de Montréal, Montreal, QC, Canada., Communal L; Centre de recherche du Centre hospitalier de l'Université de Montréal and Institut du cancer de Montréal, Montreal, QC, Canada., Mukherjee A; Akoya Biosciences, Menlo Park, CA, United States., Mes-Masson AM; Centre de recherche du Centre hospitalier de l'Université de Montréal and Institut du cancer de Montréal, Montreal, QC, Canada.; Department of Medicine, Université de Montréal, Montreal, QC, Canada., Arnason T; Department of Pathology, Dalhousie University, Halifax, NS, Canada.; Department of Pathology & Laboratory Medicine, QEII Health Sciences Centre, Nova Scotia Health (Central Zone), Halifax, NS, Canada., Nelson BH; Deeley Research Centre, British Columbia Cancer Research Institute, Victoria, BC, Canada.; Department of Biochemistry and Microbiology, University of Victoria, Victoria, BC, Canada.; Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada., Boudreau JE; Department of Microbiology and Immunology, Dalhousie University, Halifax, NS, Canada.; Beatrice Hunter Cancer Research Institute, Halifax, NS, Canada.; Department of Pathology, Dalhousie University, Halifax, NS, Canada.

Publikováno v: Frontiers in immunology [Front Immunol] 2024 Jan 22; Vol. 14, pp. 1307873. Date of Electronic Publication: 2024 Jan 22 (Print Publication: 2023).

Naturally Killing the Silent Killer: NK Cell-Based Immunotherapy for Ovarian Cancer.

Autor: Nersesian S; Department of Microbiology and Immunology, Dalhousie University, Halifax, NS, Canada.; Department of Medicine, Dalhousie University, Halifax, NS, Canada., Glazebrook H; Department of Microbiology and Immunology, Dalhousie University, Halifax, NS, Canada., Toulany J; Department of Microbiology and Immunology, Dalhousie University, Halifax, NS, Canada.; Department of Medicine, Dalhousie University, Halifax, NS, Canada., Grantham SR; Department of Microbiology and Immunology, Dalhousie University, Halifax, NS, Canada., Boudreau JE; Department of Microbiology and Immunology, Dalhousie University, Halifax, NS, Canada.; Department of Pathology, Dalhousie University, Halifax, NS, Canada.

Publikováno v: Frontiers in immunology [Front Immunol] 2019 Aug 09; Vol. 10, pp. 1782. Date of Electronic Publication: 2019 Aug 09 (Print Publication: 2019).