Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Grant N. Ko"'
Autor:
Elsa Bartlett, Grant N. Ko, Steven H. Madonick, Erica Duncan, Toby R Efferen, Arti Parwani, Phillip B. Chappell, Michael Sanfilipo, John Rotrosen, Stephen Gonzenbach, Rajive Rajan, Subhajit Chakravorty
Publikováno v:
Biological Psychiatry. 47:662-669
Background: Schizophrenics show deficits in sensorimotor gating, as measured by prepulse inhibition of acoustic startle (PPI). The goal of this investigation is to further characterize PPI and habituation deficits in schizophrenia, and to examine whe
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 73:861-865
The alpha 2-adrenergic receptor antagonist yohimbine is often used as a neuroendocrine probe in human studies, in which it is assumed to increase plasma norepinephrine (NE) by increasing sympathetic outflow. In this study we have tested that assumpti
Publikováno v:
Biological Psychiatry. 27:1165-1175
This study tested the hypothesis that combat veterans with posttraumatic stress disorder (PTSD) experience sympathetic nervous system activation in response to war-related laboratory stimuli. Circulating plasma catecholamines, vital signs, and affect
Autor:
Denis G. Baskin, Marcella Pascualy, Murray A. Raskind, Barbara J. Wilcox, Daniel M. Dorsa, Grant N. Ko
Publikováno v:
Neuroendocrinology. 51:315-319
Using 3H-prazosin, we have examined the distribution of α1-adrenergic receptors in the supraoptic and paraventricular nuclei of the human hypothalamus. Our studies show that bind
Publikováno v:
Psychopharmacology. 99:S87-S91
During the course of an official US-People's Republic of China (PRC) Joint Health Agreement, a number of Chinese investigators have come to the intramural program of the NIMH for varying periods of time. In the process of planning specific collaborat
Publikováno v:
Journal of Molecular Biology. 94:539-554
At least 20 major polypeptides encoded by the bacteriophage T7 genome have been synthesized in vitro in a protein synthesis system derived from uninfected Escherichia coli cells. Identification of these polypeptides as gene-specific products has been
Autor:
Frances Petracca, Margaret A. Miller, Daniel M. Dorsa, Denis G. Baskin, Grant N. Ko, M.M. Murburg, B.J. Wilco
Publikováno v:
Computerized Medical Imaging and Graphics. 13:37-45
Receptors for neurotransmitters can be visualized and characterized using in vitro tissue slice binding techniques and quantitative autoradiography. In this article, the general methods used in studies of this type are outlined and specific applicati
Publikováno v:
Biological Psychiatry. 20:209-215
Valproic acid (VPA), or 2-propylpentanoic acid, has an anticonvulsant effect and is used clinically in the treatment of petit mal seizures (Simon and Penry 1975). Although VPA increases brain gamma-aminobutyric acid (GABA) concentrations, the anticon
Publikováno v:
Journal of Clinical Psychopharmacology. 5:253-262
Literature concerning quantification of plasma concentrations of neuroleptics is reviewed with a particular emphasis on the radioreceptor assay. Based on previously published reports and their own data, the authors conclude that further studies on fa
Publikováno v:
Archives of general psychiatry. 45(9)
• In a study of 14 drug-free schizophrenic patients and 22 healthy control subjects, the plasma 3-methoxy-4-hydroxyphenylglycol (MHPG) level appeared to be altered by changes in clinical state. Repeated sampling in schizophrenic patients showed tha