Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Grant N, Wheeler"'
Autor:
Eudald Pascual-Carreras, Marta Marín-Barba, Sergio Castillo-Lara, Pablo Coronel-Córdoba, Marta Silvia Magri, Grant N. Wheeler, Jose Luis Gómez-Skarmeta, Josep F. Abril, Emili Saló, Teresa Adell
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Any planarian fragment regenerates the missing head and tail in the proper end. Early activation of the Wnt/β-catenin signaling pathway changes the chromatin accessibility of the cells of the posterior-facing wound to regenerate a tail.
Externí odkaz:
https://doaj.org/article/4d696ab5163e4238a799db2d227455bc
Autor:
Gi Fay Mok, Leighton Folkes, Shannon A. Weldon, Eirini Maniou, Victor Martinez-Heredia, Alice M. Godden, Ruth M. Williams, Tatjana Sauka-Spengler, Grant N. Wheeler, Simon Moxon, Andrea E. Münsterberg
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
How paraxial mesoderm formation and differentiation is regulated is unclear. Here, the authors identify accessible chromatin and gene expression signatures that define different stages of paraxial mesoderm development in the chick and identify CREs i
Externí odkaz:
https://doaj.org/article/83e65e791fea4260aa9246e9733957f6
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0219721 (2020)
Wnt/FZD signalling activity is required for spinal cord development, including the dorsal-ventral patterning of the neural tube, where it affects proliferation and specification of neurons. Wnt ligands initiate canonical, β -catenin-dependent, signa
Externí odkaz:
https://doaj.org/article/305c9f777b654b6cac6ee97d14cdbc43
Autor:
Nicole J. Ward, Darrell Green, Janet Higgins, Tamas Dalmay, Andrea Münsterberg, Simon Moxon, Grant N. Wheeler
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-13 (2018)
Abstract Background The neural crest (NC) is a class of transitory stem cell-like cells unique to vertebrate embryos. NC cells arise within the dorsal neural tube where they undergo an epithelial to mesenchymal transition in order to migrate and diff
Externí odkaz:
https://doaj.org/article/da4ff68cfb894c0cb764fb807c252d52
Publikováno v:
Biology Open, Vol 6, Iss 12, Pp 1861-1868 (2017)
Wnt signalling regulates cardiogenesis during specification of heart tissue and the morphogenetic movements necessary to form the linear heart. Wnt11-mediated non-canonical signalling promotes early cardiac development whilst Wnt11-R, which is expres
Externí odkaz:
https://doaj.org/article/ed0e06ac512349d7a32063ee9ae6a141
Publikováno v:
Methods in Molecular Biology ISBN: 9781071629819
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6e450a64559473fbdd55377a14b29dc
https://doi.org/10.1007/978-1-0716-2982-6_15
https://doi.org/10.1007/978-1-0716-2982-6_15
Publikováno v:
Methods in Molecular Biology ISBN: 9781071629819
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40a71aa9c78ecd6a56c9f8d147b02c8d
https://doi.org/10.1007/978-1-0716-2982-6_11
https://doi.org/10.1007/978-1-0716-2982-6_11
Autor:
Ruth M Williams, Robert J Winkfein, Rebecca S Ginger, Martin R Green, Paul P Schnetkamp, Grant N Wheeler
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180465 (2017)
NCKX5 is an ion exchanger expressed mostly in pigment cells; however, the functional role for this protein in melanogenesis is not clear. A variant allele of SLC24A5, the gene encoding NCKX5, has been shown to correlate with lighter skin pigmentation
Externí odkaz:
https://doaj.org/article/c91bcd42d9fe4299984c12b318e90352
Autor:
Carlos Herrera-Úbeda, Marta Marín-Barba, Enrique Navas-Pérez, Jan Gravemeyer, Beatriz Albuixech-Crespo, Grant N. Wheeler, Jordi Garcia-Fernàndez
Publikováno v:
Biology, Vol 8, Iss 3, p 61 (2019)
Homologous long non-coding RNAs (lncRNAs) are elusive to identify by sequence similarity due to their fast-evolutionary rate. Here we develop LincOFinder, a pipeline that finds conserved intergenic lncRNAs (lincRNAs) between distant related species b
Externí odkaz:
https://doaj.org/article/d739dba0f4254f7baf99dedb67728ac4
Autor:
Ayisha Ahmed, Nicole J Ward, Simon Moxon, Sara Lopez-Gomollon, Camille Viaut, Matthew L Tomlinson, Ilya Patrushev, Michael J Gilchrist, Tamas Dalmay, Dario Dotlic, Andrea E Münsterberg, Grant N Wheeler
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0138313 (2015)
MicroRNAs (miRNAs) are short, non-coding RNAs around 22 nucleotides long. They inhibit gene expression either by translational repression or by causing the degradation of the mRNAs they bind to. Many are highly conserved amongst diverse organisms and
Externí odkaz:
https://doaj.org/article/67df66c51d424b86bd3898198bbd5a00