Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Grant G. F. Mason"'
Publikováno v:
Biochemical Journal. 352:611-615
Proteasomes are complex multisubunit proteases which play a critical role in intracellular proteolysis. Immunoproteasomes, which contain three γ-interferon-inducible subunits, are a subset of proteasomes which have a specialized function in antigen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bde6bdc3a950c418339f02a8ed2b1fff
https://doi.org/10.1042/bj3520611
https://doi.org/10.1042/bj3520611
Publikováno v:
Biochemical Journal. 332:315-320
The induction of apoptosis in thymocytes by the glucocorticoid dexamethasone was used as a model system to investigate whether there are changes in 20 S and 26 S proteasome activities during apoptosis. We observed that thymocytes contain high concent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13e376f43f2b99c9ad32e93c402a7d49
https://doi.org/10.1042/bj3320315
https://doi.org/10.1042/bj3320315
Autor:
A. Jennifer Rivett, Grant G. F. Mason, Kerry I. Broadfoot, Fiona L. L. Stratford, Suchira Bose
Publikováno v:
The Biochemical journal. 378(Pt 1)
In animal cells there are several regulatory complexes which interact with 20S proteasomes and give rise to functionally distinct proteasome complexes. gamma-Interferon upregulates three immuno beta catalytic subunits of the 20S proteasome and the PA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55da2729fbdd7e8d3b94e6f158e4ede7
https://pubmed.ncbi.nlm.nih.gov/14583091
https://pubmed.ncbi.nlm.nih.gov/14583091
Autor:
A. Jennifer Rivett, Grant G. F. Mason
Publikováno v:
Proteases New Perspectives ISBN: 9783034897501
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7fb5cee34411020824c291232dc76839
https://doi.org/10.1007/978-3-0348-8737-3_4
https://doi.org/10.1007/978-3-0348-8737-3_4
Publikováno v:
FEBS Letters
The 26S proteasome complex plays a major role in the non-lysosomal degradation of intracellular proteins. Purified 26S proteasomes give a pattern of more than 40 spots on 2D-PAGE gels. The positions of subunits have been identified by mass spectromet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c24674a09c7dab425dbdbd535c22bf0
https://pubmed.ncbi.nlm.nih.gov/9688553
https://pubmed.ncbi.nlm.nih.gov/9688553
Autor:
Jill R. Beyette, Grant G. F. Mason
Publisher Summary This chapter discusses the major classes of proteases that have been ascribed roles in apoptosis and presents the evidence for their involvement in programmed cell death. Apoptosis or programmed cell death is a genetically controlle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbb1cac750597ed48b2342a116fc5cd7
https://doi.org/10.1016/s1569-2558(08)60464-6
https://doi.org/10.1016/s1569-2558(08)60464-6
Publikováno v:
Biochemical Journal. 353:291
In mammalian cells proteasomes can be activated by two different types of regulatory complexes which bind to the ends of the proteasome cylinder. Addition of two 19 S (PA700; ATPase) complexes forms the 26 S proteasome, which is responsible for ATP-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fd7631c6bc0488917f34330f5f26de2
https://doi.org/10.1042/0264-6021:3530291
https://doi.org/10.1042/0264-6021:3530291
Autor:
Shelley J Allen, Grant G. F. Mason, Ruth L Naylor, Howard A. Anderson, Stephanie K.F Smith, SJ Tyler, Gang Yu, David Dawbarn, Gordon W Wilcock, Robertson Alan George Simpson, Paul A. Roche, Paul E. Fraser
Publikováno v:
University of Bristol-PURE
Mutations in the presenilin 1 gene have been shown to result in Alzheimer's disease. Presenilin 1 is a multi-transmembrane protein with a large hydrophilic loop near the C-terminus. This region is required for known functions of presenilin 1. We have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bce7bbe231049721664e2bd190d7edc
https://research-information.bris.ac.uk/en/publications/868361d9-cafd-4e2c-b766-11b614fe2481
https://research-information.bris.ac.uk/en/publications/868361d9-cafd-4e2c-b766-11b614fe2481
Autor:
Rodney A. King, M. McLaughlin, R. Markwell, H. Wadsworth, David Allsop, S. J. Assinder, A. J. Rivett, M. C. Chabot-Fletcher, Gary Christie, J. Breton, R. C. Gardner, Grant G. F. Mason
Publikováno v:
Lancaster University-Pure
Proteasomes are large multisubunit proteinases which have several distinct catalytic sites. In this study a series of di- and tri-peptidyl boronic acids have been tested on the chymotrypsin-like activity of purified mammalian 20 S and 26 S proteasome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::897afdd2f97c0f0257369d25c4748a8a
https://puretest.lancaster.ac.uk/portal/en/publications/characterisation-of-peptidyl-boronic-acid-inhibitors-of-mammalian-20s-and-26s-proteasomes-and-their-inhibition-of-proteasomes-in-cultured-cells(a4a2bd25-a27d-4e00-a3e3-58b112af544a).html
https://puretest.lancaster.ac.uk/portal/en/publications/characterisation-of-peptidyl-boronic-acid-inhibitors-of-mammalian-20s-and-26s-proteasomes-and-their-inhibition-of-proteasomes-in-cultured-cells(a4a2bd25-a27d-4e00-a3e3-58b112af544a).html