Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Grant F Kusick"'
Autor:
Zhenyong Wu, Grant F Kusick, Manon MM Berns, Sumana Raychaudhuri, Kie Itoh, Alexander M Walter, Edwin R Chapman, Shigeki Watanabe
Publikováno v:
eLife, Vol 12 (2024)
Despite decades of intense study, the molecular basis of asynchronous neurotransmitter release remains enigmatic. Synaptotagmin (syt) 7 and Doc2 have both been proposed as Ca2+ sensors that trigger this mode of exocytosis, but conflicting findings ha
Externí odkaz:
https://doaj.org/article/a941dafebeac4bb681369387d5e79f94
Autor:
Jason D Vevea, Grant F Kusick, Kevin C Courtney, Erin Chen, Shigeki Watanabe, Edwin R Chapman
Publikováno v:
eLife, Vol 10 (2021)
Synaptotagmin 7 (SYT7) has emerged as a key regulator of presynaptic function, but its localization and precise role in the synaptic vesicle cycle remain the subject of debate. Here, we used iGluSnFR to optically interrogate glutamate release, at the
Externí odkaz:
https://doaj.org/article/17225c098b254268b655b5b6cafdb388
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 12 (2020)
The structural features of a synapse help determine its function. Synapses are extremely small and tightly packed with vesicles and other organelles. Visualizing synaptic structure requires imaging by electron microscopy, and the features in microgra
Externí odkaz:
https://doaj.org/article/8a1af260c2a24968814ea151815c57ed
Autor:
Tyler H. Ogunmowo, Haoyuan Jing, Sumana Raychaudhuri, Grant F. Kusick, Yuuta Imoto, Shuo Li, Kie Itoh, Ye Ma, Haani Jafri, Matthew B. Dalva, Edwin R. Chapman, Taekjip Ha, Shigeki Watanabe, Jian Liu
Publikováno v:
Nature Communications. 14
Compensatory endocytosis keeps the membrane surface area of secretory cells constant following exocytosis. At chemical synapses, clathrin-independent ultrafast endocytosis maintains such homeostasis. This endocytic pathway is temporally and spatially
Autor:
Haoyuan Jing, Tyler Ogunmowo, Sumana Raychaudhuri, Grant F. Kusick, Yuuta Imoto, Shuo Li, Kie Itoh, Edwin R. Chapman, Taekjip Ha, Shigeki Watanabe, Jian Liu
Compensatory endocytosis keeps the surface area of secretory cells constant following exocytosis. At chemical synapses, clathrin-independent ultrafast endocytosis maintains such homeostasis. This endocytic pathway is temporally and spatially coupled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c232e9ce8a42d4b362f1b4ce7b19118b
https://doi.org/10.1101/2022.06.12.495801
https://doi.org/10.1101/2022.06.12.495801
Publikováno v:
Curr Opin Neurobiol
As synaptic vesicles fuse, they must continually be replaced with new docked, fusion-competent vesicles to sustain neurotransmission. It has long been appreciated that vesicles are recruited to docking sites in an activity-dependent manner. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21200f24a363874bfbe322e8ea0dba4c
https://europepmc.org/articles/PMC9167714/
https://europepmc.org/articles/PMC9167714/
Autor:
Shigeki Watanabe, Edwin R. Chapman, Jason D. Vevea, Kevin C. Courtney, Erin Chen, Grant F. Kusick
Publikováno v:
eLife
eLife, Vol 10 (2021)
eLife, Vol 10 (2021)
Synaptotagmin 7 (SYT7) has emerged as a key regulator of presynaptic function, but its localization and precise role in the synaptic vesicle cycle remain the subject of debate. Here, we used iGluSnFR to optically interrogate glutamate release, at the
Autor:
Edwin R. Chapman, Kevin C. Courtney, Elizabeth H. Chen, Grant F. Kusick, Shigeki Watanabe, Jason D. Vevea
Synaptotagmin (SYT) 7 has emerged as key regulator of presynaptic function, but its localization and precise function in the synaptic vesicle cycle remain unclear. Here, we used iGluSnFR to optically and directly interrogate glutamate release, at the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58304e95a907e64bbf5a248e813dbbb6
https://doi.org/10.1101/2021.02.09.430404
https://doi.org/10.1101/2021.02.09.430404
Autor:
Hanieh Falahati, Christine Prater, Raul Ramos, Sumana Raychaudhuri, Shuo Li, Shigeki Watanabe, Tomas M. Bartol, Grant F. Kusick, Jing Wang, Eric Hosy, Marisa M Brockmann, Sarah Syed, Stephen A. Lee
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2021, 12, pp.677. ⟨10.1038/s41467-021-21004-x⟩
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications, Nature Publishing Group, 2021, 12, pp.677. ⟨10.1038/s41467-021-21004-x⟩
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Neurotransmitter is released synchronously and asynchronously following an action potential. Our recent study indicates that the release sites of these two phases are segregated within an active zone, with asynchronous release sites enriched near the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba7ed017258b1b1d22397414e4117eae
https://hal.archives-ouvertes.fr/hal-03382653
https://hal.archives-ouvertes.fr/hal-03382653