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pro vyhledávání: '"Grant English"'
Autor:
Nadège Poncet, Fiona E Mitchell, Adel F M Ibrahim, Victoria A McGuire, Grant English, J Simon C Arthur, Yun-Bo Shi, Peter M Taylor
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89547 (2014)
The System L1-type amino acid transporter mediates transport of large neutral amino acids (LNAA) in many mammalian cell-types. LNAA such as leucine are required for full activation of the mTOR-S6K signalling pathway promoting protein synthesis and ce
Externí odkaz:
https://doaj.org/article/faf64e31f1d8416fabeefd8b6f377ac6
Autor:
Sarah J. Coulthurst, Vincenzo A. Rao, Katharina Trunk, Velupillai Srikannathasan, Grant English, William N. Hunter
Publikováno v:
Molecular Microbiology; Vol 86
Molecular Microbiology
Molecular Microbiology
Protein secretion systems are critical to bacterial virulence and interactions with other organisms. The Type VI secretion system (T6SS) is found in many bacterial species and is used to target either eukaryotic cells or competitor bacteria. However,
Autor:
Grant English
Publikováno v:
Bioscience Horizons. 3:1-9
Macrophage ‘foam cells’ are the hallmark of early, and developing, atherosclerotic lesions. Generation of 27-oxygenated derivatives of cholesterol, one of the most abundant oxysterols in human atheroma, via mitochondrial sterol 27-hydroxylase (CY
Autor:
Velupillai, Srikannathasan, Grant, English, Nhat Khai, Bui, Katharina, Trunk, Patrick E F, O'Rourke, Vincenzo A, Rao, Waldemar, Vollmer, Sarah J, Coulthurst, William N, Hunter
Publikováno v:
Acta Crystallographica Section D: Biological Crystallography
Crystal structures of type VI secretion system-associated immunity proteins, a peptidoglycan endopeptidase and a complex of the endopeptidase and its cognate immunity protein are reported together with assays of endopeptidase activity and functional
Autor:
Grant English, Maurice A.M. van Steensel, Sue Lang, Steven Donnelly, Eugene A. de Zwart-Storm, Patricia Martin
Publikováno v:
Experimental Dermatology, 21(8), 592-598. Wiley
Mutations in Connexin26 (Cx26) give rise to a spectrum of dominantly inherited hyperproliferating skin disorders, the severest being keratitis-ichthyosis-deafness (KID) syndrome, an inflammatory skin disorder, with patients prone to opportunistic inf
Autor:
Grant English, Katharina Trunk, Sarah J. Coulthurst, Maximilian J. Fritsch, Sarah Murdoch, Ehsan Pourkarimi
Publikováno v:
Journal of bacteriology. 193(21)
The type VI secretion system (T6SS) is the most recently described and least understood of the protein secretion systems of Gram-negative bacteria. It is widely distributed and has been implicated in the virulence of various pathogens, but its mechan
Report
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