Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Grant C. Weaver"'
Autor:
Grant C. Weaver, Christine L. Schneider, Aniuska Becerra-Artiles, Kiera L. Clayton, Amy W. Hudson, Lawrence J. Stern
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionHuman Herpesvirus 6B (HHV-6B) impedes host immune responses by downregulating class I MHC molecules (MHC-I), hindering antigen presentation to CD8+ T cells. Downregulation of MHC-I disengages inhibitory receptors on natural killer (NK) ce
Externí odkaz:
https://doaj.org/article/b3e8081e247a4c37bd1498def231db06
Autor:
Aniuska Becerra-Artiles, J. Mauricio Calvo-Calle, Mary Dawn Co, Padma P. Nanaware, John Cruz, Grant C. Weaver, Liying Lu, Catherine Forconi, Robert W. Finberg, Ann M. Moormann, Lawrence J. Stern
Publikováno v:
Cell Reports, Vol 39, Iss 11, Pp 110952- (2022)
Summary: Sequence homology between SARS-CoV-2 and common-cold human coronaviruses (HCoVs) raises the possibility that memory responses to prior HCoV infection can affect T cell response in COVID-19. We studied T cell responses to SARS-CoV-2 and HCoVs
Externí odkaz:
https://doaj.org/article/19b6778e446541fba522ed350c80012b
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/d1bc137dd10c4b0c947a4a897345e463
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Human roseolovirus U20 and U21 are type I membrane glycoproteins that have been implicated in immune evasion by interfering with recognition of classical and non-classical MHC proteins. U20 and U21 are predicted to be type I glycoproteins with extrac
Externí odkaz:
https://doaj.org/article/d8fe77ed9b9b43929ebf429a9c2751e9
Autor:
James R. Birtley, Mohammad Alomary, Elisa Zanini, Jane Antony, Zachary Maben, Grant C. Weaver, Claudia Von Arx, Manuela Mura, Aline T. Marinho, Haonan Lu, Eloise V. N. Morecroft, Evdoxia Karali, Naomi E. Chayen, Edward W. Tate, Mollie Jurewicz, Lawrence J. Stern, Chiara Recchi, Hani Gabra
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
OPCML is a tumour suppressor gene that is epigenetically silenced in ovarian cancer and is somatically mutated in various cancers. Here, the authors solve the X-ray crystal structure of OPCML and model clinically relevant mutations that could contrib
Externí odkaz:
https://doaj.org/article/0d39746c3dc44914b53cf2c2f0ee8062
Autor:
Michael C. Jones, Catherine Castonguay, Padma P. Nanaware, Grant C. Weaver, Brian Stadinski, Olivia A. Kugler-Umana, Eric S. Huseby, Lawrence J. Stern, Karl Kai McKinstry, Tara M. Strutt, Priyadharshini Devarajan, Susan L. Swain
Publikováno v:
The Journal of Immunology.
Initial TCR affinity for peptide Ag is known to impact the generation of memory; however, its contributions later, when effectors must again recognize Ag at 5–8 d postinfection to become memory, is unclear. We examined whether the effector TCR affi
Autor:
Aniuska Becerra-Artiles, Padma P. Nanaware, Khaja Muneeruddin, Grant C. Weaver, Scott A. Shaffer, J. Mauricio Calvo-Calle, Lawrence J. Stern
Publikováno v:
bioRxiv
Seasonal “common-cold” human coronaviruses are widely spread throughout the world and are mainly associated with mild upper respiratory tract infections. The emergence of highly pathogenic coronaviruses MERS-CoV, SARS-CoV, and most recently SARS-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e6698ee4745a68c3b9b64c3dc4f2e22
https://doi.org/10.1101/2022.12.01.518643
https://doi.org/10.1101/2022.12.01.518643
Autor:
Michael C. Jones, Catherine Castonguay, Padma P. Nanaware, Grant C. Weaver, Brian Stadinski, Olivia A. Kugler-Umana, Eric Huseby, Lawrence J. Stern, Priyadharshini Devarajan, Susan L. Swain
The impact of initial peptide antigen affinity for TCR in driving memory fate has been studied previously, however its contributions when effectors contract to memory is unclear. To become memory, effector CD4 T cells must recognize antigen at 5-8 da
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e6634c0c50ff900a9b79c70a5e7bba2
https://doi.org/10.1101/2022.05.09.491158
https://doi.org/10.1101/2022.05.09.491158
Autor:
Aniuska Becerra-Artiles, J. Mauricio Calvo-Calle, Mary Dawn Co, Padma P. Nanaware, John Cruz, Grant C. Weaver, Liying Lu, Catherine Forconi, Robert W. Finberg, Ann M. Moormann, Lawrence J. Stern
Publikováno v:
Cell reports. 39(11)
Sequence homology between SARS-CoV-2 and common-cold human coronaviruses (HCoVs) raises the possibility that memory responses to prior HCoV infection can affect T cell response in COVID-19. We studied T cell responses to SARS-CoV-2 and HCoVs in conva
Autor:
Haonan Lu, Mohammad N. Alomary, Hani Gabra, Chiara Recchi, Evdoxia Karali, Edward W. Tate, Naomi E. Chayen, Manuela Mura, Zachary Maben, Grant C. Weaver, Aline T. Marinho, Mollie Jurewicz, James R. Birtley, Eloise V. N. Morecroft, Lawrence J. Stern, Jane Antony, Claudia von Arx, Elisa Zanini
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Nature Communications
Nature Communications
OPCML, a tumor suppressor gene, is frequently silenced epigenetically in ovarian and other cancers. Here we report, by analysis of databases of tumor sequences, the observation of OPCML somatic missense mutations from various tumor types and the impa