Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Grant Butt"'
Autor:
Hamish CK Angus, Paulo CM Urbano, Gemma A Laws, Shijun Fan, Safina Gadeock, Michael Schultz, Grant Butt, Andrew J Highton, Roslyn A Kemp
Publikováno v:
Clinical & Translational Immunology, Vol 11, Iss 8, Pp n/a-n/a (2022)
Abstract Objectives Crohn's disease (CD) initiation and pathogenesis are believed to involve an environmental trigger in a genetically susceptible person that results in an immune response against commensal gut bacteria, leading to a compromised inte
Externí odkaz:
https://doaj.org/article/50612b2adcad499cb4b121421df98e85
Publikováno v:
Frontiers in Medicine, Vol 6 (2020)
Inflammatory Bowel Diseases (IBD) are difficult to model as freshly acquired tissues are short-lived, provide data as a snapshot in time, and are not always accessible. Many patients with IBD are non-responders to first-line treatments, and responder
Externí odkaz:
https://doaj.org/article/fbe13b4e28064edb9a11b5e5f9534012
Autor:
Kyle Gibson, Reyna Preciado, Shujun Fan, Grant Butt, Jossue Jimenez, Declan F. McCole, Moorthy Krishnan, Rebecca R. Hernandez, Anica Sayoc-Becerra
Publikováno v:
Inflamm Bowel Dis
Inflammatory bowel diseases, vol 26, iss 3
Inflammatory bowel diseases, vol 26, iss 3
BackgroundAlterations to epithelial tight junctions can compromise the ability of the epithelium to act as a barrier between luminal contents and the underlying tissues, thereby increasing intestinal permeability, an early critical event in inflammat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f5457e678d09384b084607fd2c035a3
https://doi.org/10.1093/ibd/izz266
https://doi.org/10.1093/ibd/izz266
Publikováno v:
Frontiers in Medicine, Vol 6 (2020)
Frontiers in Medicine
Frontiers in Medicine
Inflammatory bowel diseases (IBD) are difficult to model as freshly acquired tissues are short-lived, provide data as a snapshot-in-time, and are not always accessible. Many patients with IBD are non-responders to first-line treatments, and responder
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23f8726ca8bdae535a9724de6505902e
https://www.frontiersin.org/article/10.3389/fmed.2019.00334/full
https://www.frontiersin.org/article/10.3389/fmed.2019.00334/full
Autor:
A. Grant Butt, Pin-Chun Chao
Publikováno v:
Journal of Comparative Physiology B. 187:1019-1028
In the ileum of the brushtail possum, Trichosurus vulpecula, fluid secretion appears to be driven by electrogenic HCO3 − secretion. Consistent with this, the cystic fibrosis transmembrane conductance regulator is expressed in the apical membrane of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6eec0e5f87d417890abbe94ba97a63db
https://doi.org/10.1007/s00360-017-1063-z
https://doi.org/10.1007/s00360-017-1063-z
Publikováno v:
The FASEB Journal. 33
A new milestone was reached in IBD therapeutics with the FDA approval of the Janus kinase (JAK) inhibitor, tofacitinib, for the treatment of ulcerative colitis. However, the biological mechanisms b...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::98c6e85e9011d02ff3edef9c7e017264
https://doi.org/10.1096/fasebj.2019.33.1_supplement.869.2
https://doi.org/10.1096/fasebj.2019.33.1_supplement.869.2
Autor:
Michael Schultz, Roslyn A. Kemp, Edward S Taylor, Elliott T J Dunn, A. Grant Butt, Simon Stebbings
Publikováno v:
Immunology & Cell Biology. 94:421-429
Crohn's disease (CD) is an inflammatory bowel disease characterized by patchy inflammation of the gastrointestinal tract. Ankylosing spondylitis (AS) is primarily characterized by inflammation of the lower vertebral column, and many patients with AS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcc0c4382f8f210eb173df2c808f823b
https://doi.org/10.1038/icb.2015.112
https://doi.org/10.1038/icb.2015.112
Publikováno v:
The Journal of Immunology. 204:224.4-224.4
Crohn’s disease (CD) is a type of inflammatory bowel disease caused by uncontrolled inflammation and is associated with loss of tolerance to commensal bacteria. There is no current consensus on how CD forms; however, four susceptibility criteria ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bde412efcdbd3f0d6481b87e134efa3
https://doi.org/10.4049/jimmunol.204.supp.224.4
https://doi.org/10.4049/jimmunol.204.supp.224.4
Autor:
Michael Schultz, Mark Thompson-Fawcett, Kathy Stein, A. Grant Butt, Anna Lisa Lindstroem, Glen Donaldson, Chuan Chuan Lai
Publikováno v:
Journal of Crohn's and Colitis. 9:754-762
Background: Pathogenic mechanisms responsible for the undulating symptom pattern, or indeed causative agents for the development, of inflammatory bowel diseases [IBD] are largely unknown. Many physicians and most patients are convinced that stress af
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::223e7178b3a7f0e3ea7b260c47819989
https://doi.org/10.1093/ecco-jcc/jjv098
https://doi.org/10.1093/ecco-jcc/jjv098
Publikováno v:
In Comparative Biochemistry and Physiology, Part A 2000 125(4):459-468