Výsledky vyhledávání - "Grant Budas"

Akademický článek

Non-steroidal FXR agonist cilofexor improves cholestatic liver injury in the Mdr2-/- mouse model of sclerosing cholangitis

Autor: Claudia D. Fuchs, Natalie Sroda, Hubert Scharnagl, Ruchi Gupta, Wesley Minto, Tatjana Stojakovic, John T. Liles, Grant Budas, David Hollenback, Michael Trauner

Publikováno v: JHEP Reports, Vol 5, Iss 11, Pp 100874- (2023)

Background & Aims: The nuclear receptor farnesoid X receptor (FXR) is a key regulator of hepatic bile acid (BA) and lipid metabolism, inflammation and fibrosis. Here, we aimed to explore the potential of cilofexor (GS-9674), a non-steroidal FXR agoni

Externí odkaz: https://doaj.org/article/98d4075a323d4c7285415bf45d052aaa

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Inhibition of tumour progression locus 2 (TPL2) halts the progression of liver fibrosis in a stringent long term choline deficient high-fat diet (CdHFD) rat model

Autor: Milessa Silva Afonso, Rowena Suriben, Natalie Sroda, Sowjanya Dokku, David Hollenback, Mehdi Belkhodja, Wesley Minto, Sangeetha Mahadevan, Grant Budas, Yeonju Lee, Kelli Boyd, Eda Canales, Bernard Murray, Matthew Warr, James Taylor, James Trevaskis, Ruchi Gupta

Publikováno v: Journal of Hepatology. 77:S483-S484

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::67b4d11459939d9ffb23c7139554487d
https://doi.org/10.1016/s0168-8278(22)01297-1

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CRISPR perturbation in iPSC-derived hepatic stellate cells reveals role for TNF-driven interferon response in chronic liver disease

Publikováno v: Journal of Hepatology. 77:S762

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6331c3901ef4401e5203014340269cce
https://doi.org/10.1016/s0168-8278(22)01840-2

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Glympse liver test for noninvasive monitoring of combination drug therapy in a rat model of non-alcoholic steatohepatitis (NASH)

Autor: Sophie Cazanave, Maciej Pacula, Anna Zagorska, Andrew Warren, Sarah Sherman, Eric Huang, Katie Walker, Kathy Liu, David Lopez, David Newstrom, Shiva Zaboli, Jamie Bates, John Liles, Grant Budas, David Breckenridge, Andrew Billin, Gabe Kwong

Publikováno v: Journal of Hepatology. 73:S433-S434

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a4cd55ff4a11ca1eb611998e66d0136f
https://doi.org/10.1016/s0168-8278(20)31349-0

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