Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Grant B. Frost"'
Autor:
Ronald L. Fedie, Clayton V. McNeff, Charles V. McNeff, Larry C. McNeff, Peter G. Greuel, Bingwen Yan, Julie A. Jenkins, Jason T. Brethorst, Grant B. Frost, Thomas R. Hoye
Publikováno v:
Biofuels, Bioproducts and Biorefining. 16:349-369
Autor:
Megan M. McCollum, Megan Larmore, Shingo Ishihara, Leo C.T. Ng, Louise F. Kimura, Eduardo Guadarrama, My C. Ta, Thuy N. Vien, Grant B. Frost, Karl A. Scheidt, Rachel E. Miller, Paul G. DeCaen
Publikováno v:
Cell Rep
Voltage-gated sodium channels (Na(V)) in nociceptive neurons initiate action potentials required for transmission of aberrant painful stimuli observed in osteoarthritis (OA). Targeting these Na(V) subtypes with drugs to produce analgesic effects for
Autor:
Yue Liu, Rick C. Betori, Joanna Pagacz, Grant B. Frost, Elena V. Efimova, Ding Wu, Donald J. Wolfgeher, Tracy M. Bryan, Scott B. Cohen, Karl A. Scheidt, Stephen J. Kron
Publikováno v:
Cell Chemical Biology. 29:1517-1531.e7
Beyond synthesizing telomere repeats, the telomerase reverse transcriptase (TERT) also serves multiple other roles supporting cancer growth. Blocking telomerase to drive telomere erosion appears impractical, but TERT's non-canonical activities have y
Publikováno v:
Chemistry - A European Journal. 25:1727-1732
Alkenes can be cleaved by means of the (3+2) cycloaddition and subsequent cycloreversion of 1,3-dipoles, classically ozone (O3 ), but the azide (R-N3 ) variant is rare. Chemoselectivity for these azide to alkene diazo group transfers (DGT) is typical
Autor:
Steven J. Underwood, Christopher J. Douglas, Melissa A Hardy, Nicholas A. Serratore, Grant B. Frost, Truong-Giang Hoang, Philipp M Gemmel, Constance B. Anderson
Publikováno v:
Journal of the American Chemical Society. 140(31)
One major goal of organometallic chemists is the direct functionalization of the bonds most recurrent in organic molecules: C-H, C-C, C-O, and C-N. An even grander challenge is C-C bond formation when both precursors are of this category. Parallel to
Publikováno v:
The Journal of organic chemistry. 82(7)
We studied key aspects of the mechanism of Pd-catalyzed C–CN bond activation and intramolecular enantioselective alkene cyanoamidation. An Abboud–Abraham–Kamlet–Taft (AAKT) linear solvation energy relationship (LSER) model for enantioselectiv