Quality by Design Approach for Development and Characterization of Granisetron Hydrochloride-Loaded Orodispersible Films

Autor: Ming-Yan Li, Bing Wang, Jun-Qi Zhang, Liu-Liu Yang, Jun-Tao He, Fang Chen

Publikováno v: Pharmaceutical Fronts, Vol 05, Iss 04, Pp e297-e309 (2023)

Granisetron hydrochloride can be used to prevent and treat nausea and vomiting induced by chemotherapy. Its prolonged half-life and reduced dose requirement improve patient acceptance. However, patients undergoing chemotherapy often suffer from dysph

Externí odkaz: https://doaj.org/article/0123bb2c20f5416b9cdc97de3d8dbc59

Development of novel bioadhesive granisetron hydrochloride spanlastic gel and insert for brain targeting and study their effects on rats

Autor: Rehab Abdelmonem, Mohamed el Nabarawi, Alshaimaa Attia

Publikováno v: Drug Delivery, Vol 25, Iss 1, Pp 70-77 (2018)

The aim of this study was to formulate granisetron hydrochloride (GH) spanlastic in mucoadhesive gels and lyophilized inserts for intranasal administration to improve GH bioavailability and brain targeting. Carpapol 934 and HPMC were incorporated in

Externí odkaz: https://doaj.org/article/515f5a09b69c4c71a118eac1c05a8dd6

FORMULATION AND EVALUATION OF ORODISPERSIBLE TABLETS OF GRANISETRON HYDROCHLORIDE USING PLANTAGO OVATE AS NATURAL SUPERDISINTEGRANTS

Autor: Chinmaya Keshari Sahoo, Nalini Kanta Sahoo, Madushima Sahu, V.Alagarsamy, Alok Kumar Moharana, Deepak Kumar Sarangi, Kokkula Satyanarayana

Publikováno v: Indonesian Journal of Pharmacy, Vol 27, Iss 1, Pp 35-43 (2016)

The main objective of the study was to develop orodispersible tablets of Granisetron hydrochloride, a selective 5-HT3 receptor antagonist (an antivomiting agent) for improving patient compliance, especially those of paediatric & geriatric categories

Externí odkaz: https://doaj.org/article/54c5438a818e4f26ab8daebef577595c

A clinical survey on the electrocardiogram after intravenous granisetron hydrochloride administration in clinically normal dogs

Autor: H Ghaemi, H. Salari Sedigh, M. Selk Ghaffari

Publikováno v: Περιοδικό της Ελληνικής Κτηνιατρικής Εταιρείας; Τόμ. 72 Αρ. 1 (2021); 2695-2702
Journal of the Hellenic Veterinary Medical Society; Vol. 72 No. 1 (2021); 2695-2702

ΔΕΝ ΔΙΑΤΙΘΕΤΑΙ ΠΕΡΙΛΗΨΗ
Cardiac side effect of 5-hydroxytryptamine-3 receptor antagonists has been a concern for clinicians. There is a substantial need for greater clarity about the safety of granisetron hydrochloride, an a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ca5185f8886c9336e5fc56ecb940795
https://ejournals.epublishing.ekt.gr/index.php/jhvms/article/view/26754

Development of an oil suspension containing granisetron hydrochloride as a sustained-release parenteral formulation for enhancement of pharmacokinetic properties

Autor: Han-Joo Maeng, Thi-Thao-Linh Nguyen, Van-An Duong, Sang-Cheol Chi

Publikováno v: Journal of Drug Delivery Science and Technology. 51:643-650

A sustained-release parenteral formulation of granisetron hydrochloride, a water-soluble drug, was developed in the form of an oil suspension loaded with microparticles. Spray drying technique was employed to prepare microparticles of polymers and th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b644f03b0b8175c6087d1f76de0c1f15
https://doi.org/10.1016/j.jddst.2019.03.042