Tick-borne encephalitis: A comprehensive review of the epidemiology, virology, and clinical picture.

Autor: Chiffi G; Department for BioMedical Research, University of Bern, Bern, Switzerland.; Institute for Infectious Diseases, University of Bern, Bern, Switzerland., Grandgirard D; Institute for Infectious Diseases, University of Bern, Bern, Switzerland., Leib SL; Institute for Infectious Diseases, University of Bern, Bern, Switzerland., Chrdle A; Department of Infectious Diseases, Hospital Ceske Budejovice, Ceske Budejovice, Czech Republic.; Faculty of Health and Social Sciences, University of South Bohemia, Ceske Budejovice, Czech Republic.; Royal Liverpool University Hospital, Liverpool, UK., Růžek D; Veterinary Research Institute, Emerging Viral Diseases, Brno, Czech Republic.; Department of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czech Republic.; Institute of Parasitology, Biology Centre of the Czech Academy of Sciences, Ceske Budejovice, Czech Republic.

Publikováno v: Reviews in medical virology [Rev Med Virol] 2023 Sep; Vol. 33 (5), pp. e2470. Date of Electronic Publication: 2023 Jul 01.

Efficacy assessment of a novel endolysin PlyAZ3aT for the treatment of ceftriaxone-resistant pneumococcal meningitis in an infant rat model

Autor: Valente, L.G., Le, N.D., Pitton, M., Chiffi, G., Grandgirard, D., Jakob, S.M., Cameron, D.R., Resch, G., Que, Y.A., Leib, S.L.

Publikováno v: PloS one, vol. 17, no. 4, pp. e0266928

Treatment failure in pneumococcal meningitis due to antibiotic resistance is an increasing clinical challenge and alternatives to antibiotics warrant investigation. Phage-derived endolysins efficiently kill gram-positive bacteria including multi-drug

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::4005b59ddb5efd55d25bb604c04f1777
https://pubmed.ncbi.nlm.nih.gov/35472061

Meningitis-associated pneumococcal serotype 8, ST 53, strain is hypervirulent in a rat model and has non-haemolytic pneumolysin which can be attenuated by liposomes.

Autor: Müller A; Institute for Infectious Diseases, Faculty of Medicine, University of Bern, Bern, Switzerland.; Graduate School for Cellular and Biomedical Sciences, Faculty of Medicine, University of Bern, Bern, Switzerland., Lekhuleni C; Centre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases, Division of the National Health Laboratory Service, Johannesburg, South Africa.; School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., Hupp S; Institute of Anatomy, University of Bern, Bern, Switzerland., du Plessis M; Centre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases, Division of the National Health Laboratory Service, Johannesburg, South Africa.; School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., Holivololona L; Institute for Infectious Diseases, Faculty of Medicine, University of Bern, Bern, Switzerland., Babiychuk E; Institute of Anatomy, University of Bern, Bern, Switzerland., Leib SL; Institute for Infectious Diseases, Faculty of Medicine, University of Bern, Bern, Switzerland., Grandgirard D; Institute for Infectious Diseases, Faculty of Medicine, University of Bern, Bern, Switzerland., Iliev AI; Institute of Anatomy, University of Bern, Bern, Switzerland., von Gottberg A; Centre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases, Division of the National Health Laboratory Service, Johannesburg, South Africa.; School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa., Hathaway LJ; Institute for Infectious Diseases, Faculty of Medicine, University of Bern, Bern, Switzerland.

Publikováno v: Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2023 Jan 06; Vol. 12, pp. 1106063. Date of Electronic Publication: 2023 Jan 06 (Print Publication: 2022).

Tick-borne encephalitis affects sleep-wake behavior and locomotion in infant rats.

Autor: Chiffi G; Neuroinfection Laboratory, Institute for Infectious Diseases, University of Bern, Friedbühlstrasse 51, 3001, Bern, Switzerland.; Graduate School for Cellular and Biomedical Sciences (GCB), University of Bern, Bern, Switzerland., Grandgirard D; Neuroinfection Laboratory, Institute for Infectious Diseases, University of Bern, Friedbühlstrasse 51, 3001, Bern, Switzerland., Stöckli S; Neuroinfection Laboratory, Institute for Infectious Diseases, University of Bern, Friedbühlstrasse 51, 3001, Bern, Switzerland., Valente LG; Neuroinfection Laboratory, Institute for Infectious Diseases, University of Bern, Friedbühlstrasse 51, 3001, Bern, Switzerland.; Graduate School for Cellular and Biomedical Sciences (GCB), University of Bern, Bern, Switzerland., Adamantidis A; Department of Neurology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Leib SL; Neuroinfection Laboratory, Institute for Infectious Diseases, University of Bern, Friedbühlstrasse 51, 3001, Bern, Switzerland. stephen.leib@ifik.unibe.ch.

Publikováno v: Cell & bioscience [Cell Biosci] 2022 Aug 02; Vol. 12 (1), pp. 121. Date of Electronic Publication: 2022 Aug 02.

CNS Antigen-Specific Neuroinflammation Attenuates Ischemic Stroke With Involvement of Polarized Myeloid Cells.

Autor: Guse K; From the Department of Neurology (K.G., L.T., J.R., A.S., R.H., A.C.), Inselspital, Bern University Hospital, Department for BioMedical Research (DBMR), University of Bern, Switzerland; Department of Neurology (K.G., L.T.), St. Josef-Hospital, Ruhr-University, Bochum, Germany; Department of Neurology (N.H., D.M.H.), Chair of Vascular Neurology, Dementia and Ageing Research, University of Duisburg-Essen, Germany; Interfaculty Bioinformatics Unit and Swiss Institute of Bioinformatics (I.K.), Department for BioMedical Research (DBMR), Neuroinfection Laboratory (P.M., D.G., S.L.L.), Institute for Infectious Diseases, Institute of Pathology (E.V.), and Theodor Kocher Institute (G.L.), University of Bern, Switzerland., Hagemann N; From the Department of Neurology (K.G., L.T., J.R., A.S., R.H., A.C.), Inselspital, Bern University Hospital, Department for BioMedical Research (DBMR), University of Bern, Switzerland; Department of Neurology (K.G., L.T.), St. Josef-Hospital, Ruhr-University, Bochum, Germany; Department of Neurology (N.H., D.M.H.), Chair of Vascular Neurology, Dementia and Ageing Research, University of Duisburg-Essen, Germany; Interfaculty Bioinformatics Unit and Swiss Institute of Bioinformatics (I.K.), Department for BioMedical Research (DBMR), Neuroinfection Laboratory (P.M., D.G., S.L.L.), Institute for Infectious Diseases, Institute of Pathology (E.V.), and Theodor Kocher Institute (G.L.), University of Bern, Switzerland., Thiele L; From the Department of Neurology (K.G., L.T., J.R., A.S., R.H., A.C.), Inselspital, Bern University Hospital, Department for BioMedical Research (DBMR), University of Bern, Switzerland; Department of Neurology (K.G., L.T.), St. Josef-Hospital, Ruhr-University, Bochum, Germany; Department of Neurology (N.H., D.M.H.), Chair of Vascular Neurology, Dementia and Ageing Research, University of Duisburg-Essen, Germany; Interfaculty Bioinformatics Unit and Swiss Institute of Bioinformatics (I.K.), Department for BioMedical Research (DBMR), Neuroinfection Laboratory (P.M., D.G., S.L.L.), Institute for Infectious Diseases, Institute of Pathology (E.V.), and Theodor Kocher Institute (G.L.), University of Bern, Switzerland., Remlinger J; From the Department of Neurology (K.G., L.T., J.R., A.S., R.H., A.C.), Inselspital, Bern University Hospital, Department for BioMedical Research (DBMR), University of Bern, Switzerland; Department of Neurology (K.G., L.T.), St. Josef-Hospital, Ruhr-University, Bochum, Germany; Department of Neurology (N.H., D.M.H.), Chair of Vascular Neurology, Dementia and Ageing Research, University of Duisburg-Essen, Germany; Interfaculty Bioinformatics Unit and Swiss Institute of Bioinformatics (I.K.), Department for BioMedical Research (DBMR), Neuroinfection Laboratory (P.M., D.G., S.L.L.), Institute for Infectious Diseases, Institute of Pathology (E.V.), and Theodor Kocher Institute (G.L.), University of Bern, Switzerland., Salmen A; From the Department of Neurology (K.G., L.T., J.R., A.S., R.H., A.C.), Inselspital, Bern University Hospital, Department for BioMedical Research (DBMR), University of Bern, Switzerland; Department of Neurology (K.G., L.T.), St. Josef-Hospital, Ruhr-University, Bochum, Germany; Department of Neurology (N.H., D.M.H.), Chair of Vascular Neurology, Dementia and Ageing Research, University of Duisburg-Essen, Germany; Interfaculty Bioinformatics Unit and Swiss Institute of Bioinformatics (I.K.), Department for BioMedical Research (DBMR), Neuroinfection Laboratory (P.M., D.G., S.L.L.), Institute for Infectious Diseases, Institute of Pathology (E.V.), and Theodor Kocher Institute (G.L.), University of Bern, Switzerland., Hoepner R; From the Department of Neurology (K.G., L.T., J.R., A.S., R.H., A.C.), Inselspital, Bern University Hospital, Department for BioMedical Research (DBMR), University of Bern, Switzerland; Department of Neurology (K.G., L.T.), St. Josef-Hospital, Ruhr-University, Bochum, Germany; Department of Neurology (N.H., D.M.H.), Chair of Vascular Neurology, Dementia and Ageing Research, University of Duisburg-Essen, Germany; Interfaculty Bioinformatics Unit and Swiss Institute of Bioinformatics (I.K.), Department for BioMedical Research (DBMR), Neuroinfection Laboratory (P.M., D.G., S.L.L.), Institute for Infectious Diseases, Institute of Pathology (E.V.), and Theodor Kocher Institute (G.L.), University of Bern, Switzerland., Keller I; From the Department of Neurology (K.G., L.T., J.R., A.S., R.H., A.C.), Inselspital, Bern University Hospital, Department for BioMedical Research (DBMR), University of Bern, Switzerland; Department of Neurology (K.G., L.T.), St. Josef-Hospital, Ruhr-University, Bochum, Germany; Department of Neurology (N.H., D.M.H.), Chair of Vascular Neurology, Dementia and Ageing Research, University of Duisburg-Essen, Germany; Interfaculty Bioinformatics Unit and Swiss Institute of Bioinformatics (I.K.), Department for BioMedical Research (DBMR), Neuroinfection Laboratory (P.M., D.G., S.L.L.), Institute for Infectious Diseases, Institute of Pathology (E.V.), and Theodor Kocher Institute (G.L.), University of Bern, Switzerland., Meyer P; From the Department of Neurology (K.G., L.T., J.R., A.S., R.H., A.C.), Inselspital, Bern University Hospital, Department for BioMedical Research (DBMR), University of Bern, Switzerland; Department of Neurology (K.G., L.T.), St. Josef-Hospital, Ruhr-University, Bochum, Germany; Department of Neurology (N.H., D.M.H.), Chair of Vascular Neurology, Dementia and Ageing Research, University of Duisburg-Essen, Germany; Interfaculty Bioinformatics Unit and Swiss Institute of Bioinformatics (I.K.), Department for BioMedical Research (DBMR), Neuroinfection Laboratory (P.M., D.G., S.L.L.), Institute for Infectious Diseases, Institute of Pathology (E.V.), and Theodor Kocher Institute (G.L.), University of Bern, Switzerland., Grandgirard D; From the Department of Neurology (K.G., L.T., J.R., A.S., R.H., A.C.), Inselspital, Bern University Hospital, Department for BioMedical Research (DBMR), University of Bern, Switzerland; Department of Neurology (K.G., L.T.), St. Josef-Hospital, Ruhr-University, Bochum, Germany; Department of Neurology (N.H., D.M.H.), Chair of Vascular Neurology, Dementia and Ageing Research, University of Duisburg-Essen, Germany; Interfaculty Bioinformatics Unit and Swiss Institute of Bioinformatics (I.K.), Department for BioMedical Research (DBMR), Neuroinfection Laboratory (P.M., D.G., S.L.L.), Institute for Infectious Diseases, Institute of Pathology (E.V.), and Theodor Kocher Institute (G.L.), University of Bern, Switzerland., Leib SL; From the Department of Neurology (K.G., L.T., J.R., A.S., R.H., A.C.), Inselspital, Bern University Hospital, Department for BioMedical Research (DBMR), University of Bern, Switzerland; Department of Neurology (K.G., L.T.), St. Josef-Hospital, Ruhr-University, Bochum, Germany; Department of Neurology (N.H., D.M.H.), Chair of Vascular Neurology, Dementia and Ageing Research, University of Duisburg-Essen, Germany; Interfaculty Bioinformatics Unit and Swiss Institute of Bioinformatics (I.K.), Department for BioMedical Research (DBMR), Neuroinfection Laboratory (P.M., D.G., S.L.L.), Institute for Infectious Diseases, Institute of Pathology (E.V.), and Theodor Kocher Institute (G.L.), University of Bern, Switzerland., Vassella E; From the Department of Neurology (K.G., L.T., J.R., A.S., R.H., A.C.), Inselspital, Bern University Hospital, Department for BioMedical Research (DBMR), University of Bern, Switzerland; Department of Neurology (K.G., L.T.), St. Josef-Hospital, Ruhr-University, Bochum, Germany; Department of Neurology (N.H., D.M.H.), Chair of Vascular Neurology, Dementia and Ageing Research, University of Duisburg-Essen, Germany; Interfaculty Bioinformatics Unit and Swiss Institute of Bioinformatics (I.K.), Department for BioMedical Research (DBMR), Neuroinfection Laboratory (P.M., D.G., S.L.L.), Institute for Infectious Diseases, Institute of Pathology (E.V.), and Theodor Kocher Institute (G.L.), University of Bern, Switzerland., Locatelli G; From the Department of Neurology (K.G., L.T., J.R., A.S., R.H., A.C.), Inselspital, Bern University Hospital, Department for BioMedical Research (DBMR), University of Bern, Switzerland; Department of Neurology (K.G., L.T.), St. Josef-Hospital, Ruhr-University, Bochum, Germany; Department of Neurology (N.H., D.M.H.), Chair of Vascular Neurology, Dementia and Ageing Research, University of Duisburg-Essen, Germany; Interfaculty Bioinformatics Unit and Swiss Institute of Bioinformatics (I.K.), Department for BioMedical Research (DBMR), Neuroinfection Laboratory (P.M., D.G., S.L.L.), Institute for Infectious Diseases, Institute of Pathology (E.V.), and Theodor Kocher Institute (G.L.), University of Bern, Switzerland., Hermann DM; From the Department of Neurology (K.G., L.T., J.R., A.S., R.H., A.C.), Inselspital, Bern University Hospital, Department for BioMedical Research (DBMR), University of Bern, Switzerland; Department of Neurology (K.G., L.T.), St. Josef-Hospital, Ruhr-University, Bochum, Germany; Department of Neurology (N.H., D.M.H.), Chair of Vascular Neurology, Dementia and Ageing Research, University of Duisburg-Essen, Germany; Interfaculty Bioinformatics Unit and Swiss Institute of Bioinformatics (I.K.), Department for BioMedical Research (DBMR), Neuroinfection Laboratory (P.M., D.G., S.L.L.), Institute for Infectious Diseases, Institute of Pathology (E.V.), and Theodor Kocher Institute (G.L.), University of Bern, Switzerland., Chan A; From the Department of Neurology (K.G., L.T., J.R., A.S., R.H., A.C.), Inselspital, Bern University Hospital, Department for BioMedical Research (DBMR), University of Bern, Switzerland; Department of Neurology (K.G., L.T.), St. Josef-Hospital, Ruhr-University, Bochum, Germany; Department of Neurology (N.H., D.M.H.), Chair of Vascular Neurology, Dementia and Ageing Research, University of Duisburg-Essen, Germany; Interfaculty Bioinformatics Unit and Swiss Institute of Bioinformatics (I.K.), Department for BioMedical Research (DBMR), Neuroinfection Laboratory (P.M., D.G., S.L.L.), Institute for Infectious Diseases, Institute of Pathology (E.V.), and Theodor Kocher Institute (G.L.), University of Bern, Switzerland. andrew.chan@insel.ch.

Publikováno v: Neurology(R) neuroimmunology & neuroinflammation [Neurol Neuroimmunol Neuroinflamm] 2022 Jun 08; Vol. 9 (4). Date of Electronic Publication: 2022 Jun 08 (Print Publication: 2022).