SPP1/osteopontin: a driver of fibrosis and inflammation in degenerative ascending aortic aneurysm?

Autor: Freiholtz D; Section of Cardiothoracic Surgery, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.; Division of Cardiovascular Medicine, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Karolinska University Hospital, Solna, Sweden., Bergman O; Division of Cardiovascular Medicine, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Karolinska University Hospital, Solna, Sweden., Pradhananga S; KTH Royal Institute of Technology, School of Chemistry, Biotechnology and Health, Science for Life Laboratory, Tomtebodavägen 23A, 171 65, Stockholm, Sweden., Lång K; Division of Cardiovascular Medicine, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Karolinska University Hospital, Solna, Sweden., Poujade FA; Division of Cardiovascular Medicine, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Karolinska University Hospital, Solna, Sweden., Granath C; Section of Cardiothoracic Surgery, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.; Division of Cardiovascular Medicine, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Karolinska University Hospital, Solna, Sweden., Olsson C; Section of Cardiothoracic Surgery, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden., Franco-Cereceda A; Section of Cardiothoracic Surgery, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden., Sahlén P; KTH Royal Institute of Technology, School of Chemistry, Biotechnology and Health, Science for Life Laboratory, Tomtebodavägen 23A, 171 65, Stockholm, Sweden., Eriksson P; Division of Cardiovascular Medicine, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Karolinska University Hospital, Solna, Sweden., Björck HM; Division of Cardiovascular Medicine, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Karolinska University Hospital, Solna, Sweden. hanna.bjorck@ki.se.

Publikováno v: Journal of molecular medicine (Berlin, Germany) [J Mol Med (Berl)] 2023 Oct; Vol. 101 (10), pp. 1323-1333. Date of Electronic Publication: 2023 Sep 12.

Possible role of SPP1 in degenerative ascending aortic aneurysm formation

Autor: Freiholtz, D., Bergman, O., Poujade, F.-A., Granath, C., Lång, K., Olsson, C., Franco-Cereceda, A., Björck, H.M., Eriksson, P.

Publikováno v: In Atherosclerosis August 2023 379 Supplement 1:S31-S31

Valve disease and aortopathy associations of bicuspid aortic valve phenotypes differ between men and women.

Autor: Granath C; Department of Molecular Medicine and Surgery, Section of Cardiothoracic Surgery, Karolinska Institutet, Stockholm, Sweden., Mohamed SA; Department of Cardiac and Thoracic Vascular Surgery, Universitätsklinikum Schleswig-Holstein Campus Lübeck, Lubeck, Germany., Olsson C; Department of Molecular Medicine and Surgery, Section of Cardiothoracic Surgery, Karolinska Institutet, Stockholm, Sweden.; Department of Thoracic and Cardiovascular Surgery, Karolinska University Hospital, Stockholm, Sweden., Grattan M; Department of Paediatrics, LHSC Children's Hospital, University of Western Ontario, London, Ontario, Canada.; Department of Paediatrics, Division of Cardiology, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada., Mertens L; Department of Paediatrics, Division of Cardiology, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada., Franco-Cereceda A; Department of Molecular Medicine and Surgery, Section of Cardiothoracic Surgery, Karolinska Institutet, Stockholm, Sweden.; Department of Thoracic and Cardiovascular Surgery, Karolinska University Hospital, Stockholm, Sweden., Björck HM; Department of Medicine, Cardiovascular Medicine Unit, Center for Molecular Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden Hanna.Bjorck@ki.se.

Publikováno v: Open heart [Open Heart] 2021 Oct; Vol. 8 (2).

Characterization of Laminins in Healthy Human Aortic Valves and a Modified Decellularized Rat Scaffold.

Autor: Granath C; Division of Cardiothoracic Surgery, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden., Noren H; Cell Therapy Institute, Dr. Kiran C. Patel College of Allopathic Medicine, Nova Southeastern University, Davie, Florida, USA., Björck H; Cardiovascular Medicine Unit, Department of Medicine, Center for Molecular Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden., Simon N; Cardiovascular Medicine Unit, Department of Medicine, Center for Molecular Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden., Olesen K; Division of Cardiothoracic Surgery, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.; Department of Bioscience, University of Skövde, Skövde, Sweden.; Department of Chemistry, Ångström Laboratory, Uppsala University, Uppsala, Sweden., Rodin S; Chemistry I, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.; Division of Cardiothoracic Surgery and Anesthesiology, Department of Surgical Sciences, Uppsala University, Akademiska University Hospital, Uppsala, Sweden., Grinnemo KH; Division of Cardiothoracic Surgery, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.; Division of Cardiothoracic Surgery and Anesthesiology, Department of Surgical Sciences, Uppsala University, Akademiska University Hospital, Uppsala, Sweden., Österholm C; Division of Clinical Genetics, Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.

Publikováno v: BioResearch open access [Biores Open Access] 2020 Dec 07; Vol. 9 (1), pp. 269-278. Date of Electronic Publication: 2020 Dec 07 (Print Publication: 2020).

Quantification of cardiac capillarization in basement-membrane-immunostained myocardial slices using Segment Anything Model.

Autor: Zhang, Zhao¹ (AUTHOR), Chen, Xiwen² (AUTHOR), Richardson, William³ (AUTHOR), Gao, Bruce Z.¹ (AUTHOR), Razi, Abolfazl² (AUTHOR), Ye, Tong^1,4 (AUTHOR) ye7@clemson.edu

Publikováno v: Scientific Reports. 7/3/2024, Vol. 14 Issue 1, p1-11. 11p.