CD22 CAR T cells demonstrate high response rates and safety in pediatric and adult B-ALL: Phase 1b results.

Autor: Schultz LM; Division of Pediatric Hematology/Oncology, Stanford University, Stanford, CA, USA.; Center for Cancer Cell Therapy, Stanford University, Stanford, CA, USA., Jeyakumar N; Division of Hematology, Stanford University, Stanford, CA, USA., Kramer AM; Center for Cancer Cell Therapy, Stanford University, Stanford, CA, USA., Sahaf B; Center for Cancer Cell Therapy, Stanford University, Stanford, CA, USA., Srinagesh H; Division of Hematology, Stanford University, Stanford, CA, USA., Shiraz P; Division of Blood and Marrow Transplantation and Cellular Therapy, Stanford University, Stanford, CA, USA., Agarwal N; Division of Blood and Marrow Transplantation and Cellular Therapy, Stanford University, Stanford, CA, USA., Hamilton M; Division of Hematology, Stanford University, Stanford, CA, USA., Erickson C; Division of Pediatric Hematology/Oncology, Stanford University, Stanford, CA, USA., Jacobs A; Division of Pediatric Hematology/Oncology, Stanford University, Stanford, CA, USA., Moon J; Division of Pediatric Hematology/Oncology, Stanford University, Stanford, CA, USA., Baggott C; Division of Pediatric Hematology/Oncology, Stanford University, Stanford, CA, USA., Arai S; Division of Blood and Marrow Transplantation and Cellular Therapy, Stanford University, Stanford, CA, USA., Bharadwaj S; Division of Blood and Marrow Transplantation and Cellular Therapy, Stanford University, Stanford, CA, USA., Johnston LJ; Division of Blood and Marrow Transplantation and Cellular Therapy, Stanford University, Stanford, CA, USA., Liedtke M; Division of Hematology, Stanford University, Stanford, CA, USA., Lowsky R; Division of Blood and Marrow Transplantation and Cellular Therapy, Stanford University, Stanford, CA, USA., Meyer E; Division of Blood and Marrow Transplantation and Cellular Therapy, Stanford University, Stanford, CA, USA., Negrin R; Division of Blood and Marrow Transplantation and Cellular Therapy, Stanford University, Stanford, CA, USA., Rezvani A; Division of Blood and Marrow Transplantation and Cellular Therapy, Stanford University, Stanford, CA, USA., Shizuru J; Division of Blood and Marrow Transplantation and Cellular Therapy, Stanford University, Stanford, CA, USA., Sidana S; Division of Blood and Marrow Transplantation and Cellular Therapy, Stanford University, Stanford, CA, USA., Egeler E; Center for Cancer Cell Therapy, Stanford University, Stanford, CA, USA., Mavroukakis S; Center for Cancer Cell Therapy, Stanford University, Stanford, CA, USA., Tunuguntla R; Laboratory for Cell and Gene Medicine, Stanford University, Stanford, CA, USA., Gkitsas-Long N; Laboratory for Cell and Gene Medicine, Stanford University, Stanford, CA, USA., Retherford A; Laboratory for Cell and Gene Medicine, Stanford University, Stanford, CA, USA., Brown AK; Laboratory for Cell and Gene Medicine, Stanford University, Stanford, CA, USA., Gramstrap-Petersen AL; Laboratory for Cell and Gene Medicine, Stanford University, Stanford, CA, USA., Ibañez RM; Laboratory for Cell and Gene Medicine, Stanford University, Stanford, CA, USA., Feldman SA; Center for Cancer Cell Therapy, Stanford University, Stanford, CA, USA.; Laboratory for Cell and Gene Medicine, Stanford University, Stanford, CA, USA., Miklos DB; Center for Cancer Cell Therapy, Stanford University, Stanford, CA, USA.; Division of Blood and Marrow Transplantation and Cellular Therapy, Stanford University, Stanford, CA, USA., Mackall CL; Division of Pediatric Hematology/Oncology, Stanford University, Stanford, CA, USA.; Center for Cancer Cell Therapy, Stanford University, Stanford, CA, USA., Davis KL; Division of Pediatric Hematology/Oncology, Stanford University, Stanford, CA, USA.; Center for Cancer Cell Therapy, Stanford University, Stanford, CA, USA., Frank M; Center for Cancer Cell Therapy, Stanford University, Stanford, CA, USA.; Division of Blood and Marrow Transplantation and Cellular Therapy, Stanford University, Stanford, CA, USA., Ramakrishna S; Division of Pediatric Hematology/Oncology, Stanford University, Stanford, CA, USA.; Center for Cancer Cell Therapy, Stanford University, Stanford, CA, USA., Muffly L; Center for Cancer Cell Therapy, Stanford University, Stanford, CA, USA. lmuffly@stanford.edu.; Division of Blood and Marrow Transplantation and Cellular Therapy, Stanford University, Stanford, CA, USA. lmuffly@stanford.edu.

Publikováno v: Leukemia [Leukemia] 2024 May; Vol. 38 (5), pp. 963-968. Date of Electronic Publication: 2024 Mar 15.